Search Results - "Ghosh, Saikat Kumar B."
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1
Kinetic Competition between Elongation Rate and Binding of NELF Controls Promoter-Proximal Pausing
Published in Molecular cell (06-06-2013)“…Pausing of RNA polymerase II (Pol II) 20–60 bp downstream of transcription start sites is a major checkpoint during transcription in animal cells. Mechanisms…”
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2
Double strand RNA delivery system for plant-sap-feeding insects
Published in PloS one (09-02-2017)“…Double-stranded RNA (dsRNA)-mediated gene silencing, also known as RNA interference (RNAi), has been a breakthrough technology for functional genomic studies…”
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3
The histological analysis of the coronary medial thickness: Implications for percutaneous coronary intervention
Published in PloS one (31-03-2023)“…A deeper understanding of coronary medial thickness is important for coronary intervention because media thickness can limit the safety and effectiveness of…”
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4
NELF-mediated stalling of Pol II can enhance gene expression by blocking promoter-proximal nucleosome assembly
Published in Genes & development (15-07-2008)“…The Negative Elongation Factor (NELF) is a transcription regulatory complex that induces stalling of RNA polymerase II (Pol II) during early transcription…”
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5
Enhanced Thromboresistance and Endothelialization of a Novel Fluoropolymer-Coated Left Atrial Appendage Closure Device
Published in JACC. Clinical electrophysiology (01-08-2023)“…Device-related thrombus (DRT) after left atrial appendage closure (LAAC) procedures is a rare but potentially serious event. Thrombogenicity and delayed…”
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6
Negative Elongation Factor Accelerates the Rate at Which Heat Shock Genes Are Shut off by Facilitating Dissociation of Heat Shock Factor
Published in Molecular and Cellular Biology (01-10-2011)“…Article Usage Stats Services MCB Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley…”
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7
Double strand RNA-mediated RNA interference through feeding in larval gypsy moth, Lymantria dispar (Lepidoptera: Erebidae)
Published in European journal of entomology (01-01-2017)“…RNA interference (RNAi) technology uses dsRNAs to silence specific targeted genes by downregulating their expression. It has become a potent tool for…”
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8
Opportunities and Challenges in Understanding Atherosclerosis by Human Biospecimen Studies
Published in Frontiers in cardiovascular medicine (07-07-2022)“…Over the last few years, new high-throughput biotechnologies and bioinformatic methods are revolutionizing our way of deep profiling tissue specimens at the…”
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9
Histologic Assessment of Thromboemboli Due to Plaque Rupture, Plaque Erosion, or COVID-19 Microthrombi
Published in JACC. Case reports (17-05-2023)“…Plaque rupture, plaque erosion, and COVID-19 infection can cause acute coronary syndromes (ACS). We illustrate case examples demonstrating the distinctive and…”
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10
Native tertiary structure and nucleoside modifications suppress tRNA's intrinsic ability to activate the innate immune sensor PKR
Published in PloS one (04-03-2013)“…Interferon inducible protein kinase PKR is an essential component of innate immunity. It is activated by long stretches of dsRNA and provides the first line of…”
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11
Cabbage looper (Trichoplusia ni Hübner) labial glands contain unique bacterial flora in contrast with their alimentary canal, mandibular glands, and Malpighian tubules
Published in MicrobiologyOpen (Weinheim) (01-04-2020)“…In recent years, several studies have examined the gut microbiome of lepidopteran larvae and how factors such as host plant affect it, and in turn, how gut…”
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12
Double-stranded RNA Oral Delivery Methods to Induce RNA Interference in Phloem and Plant-sap-feeding Hemipteran Insects
Published in Journal of visualized experiments (04-05-2018)“…Phloem and plant sap feeding insects invade the integrity of crops and fruits to retrieve nutrients, in the process damaging food crops. Hemipteran insects…”
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13
Single-nucleus chromatin accessibility profiling highlights regulatory mechanisms of coronary artery disease risk
Published in Nature genetics (01-06-2022)“…Coronary artery disease (CAD) is a complex inflammatory disease involving genetic influences across cell types. Genome-wide association studies have identified…”
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14
Secreted Protein Profiling of Human Aortic Smooth Muscle Cells Identifies Vascular Disease Associations
Published in Arteriosclerosis, thrombosis, and vascular biology (01-04-2024)“…Smooth muscle cells (SMCs), which make up the medial layer of arteries, are key cell types involved in cardiovascular disease, the leading cause of mortality…”
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15
Clonal Proliferation Within Smooth Muscle Cells in Unstable Human Atherosclerotic Lesions
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2023)“…Studies in humans and mice using the expression of an X-linked gene or lineage tracing, respectively, have suggested that clones of smooth muscle cells (SMCs)…”
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16
Histology, OCT, and Micro-CT Evaluation of Coronary Calcification Treated With Intravascular Lithotripsy: Atherosclerotic Cadaver Study
Published in JACC. Cardiovascular interventions (11-09-2023)“…Although intravascular lithotripsy (IVL) has been an emerging novel option to treat vascular calcification, the specific effects on histology have not been…”
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17
De novo formation of an aggregation pheromone precursor by an isoprenyl diphosphate synthase-related terpene synthase in the harlequin bug
Published in Proceedings of the National Academy of Sciences - PNAS (11-09-2018)“…Insects use a diverse array of specialized terpene metabolites as pheromones in intraspecific interactions. In contrast to plants and microbes, which employ…”
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18
Mechanisms of Medial Wall Thinning in Chronic Total Occlusion
Published in JACC. Cardiovascular interventions (22-07-2024)“…The success rate of percutaneous coronary intervention (PCI) for chronic total occlusion (CTO) is lower and the risk for complications higher compared with…”
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19
CD163 + Macrophages Induce Endothelial-to-Mesenchymal Transition in Atheroma
Published in Circulation research (05-07-2024)“…Cell phenotype switching is increasingly being recognized in atherosclerosis. However, our understanding of the exact stimuli for such cellular transformations…”
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20
Relationships between neighborhood disadvantage and cardiovascular findings at autopsy in subjects with sudden death
Published in The American heart journal (01-02-2023)“…Neighborhood disadvantage is associated with a higher risk of sudden cardiac death. However, autopsy findings have never been investigated in this context…”
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