Search Results - "Ghosh, Nilabh"

L-Ala-L-Gln Suppresses Hypoxic Phenotype and Fibrogenic Activity of Rat Perineurial Fibroblasts by Ghosh, Nilabh, Bregere, Catherine, Bustos, Pia, Guzman, Raphael

“…Twenty million Americans suffer from peripheral nerve injury (PNI) and approximately $150 billion is spent annually in the United States for the treatment of…”
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Reporting quality of clinical trial protocols: a repeated cross-sectional study about the Adherence to SPIrit Recommendations in Switzerland, CAnada and GErmany (ASPIRE-SCAGE) by Gryaznov, Dmitry, von Niederhäusern, Belinda, Speich, Benjamin, Kasenda, Benjamin, Ojeda-Ruiz, Elena, Blümle, Anette, Schandelmaier, Stefan, Mertz, Dominik, Odutayo, Ayodele, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Lohner, Szimonetta, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Meerpohl, Joerg J, Nordmann, Alain, Klatte, Katharina, Ghosh, Nilabh, Taji Heravi, Ala, Wong, Jacqueline, Chow, Ngai, Hong, Patrick, McCord - De Iaco, Kimberly A, Sricharoenchai, Sirintip, Busse, Jason W, Agarwal, Arnav, Saccilotto, Ramon, Schwenkglenks, Matthias, Moffa, Giusi, Hemkens, Lars, Hopewell, Sally, Von Elm, Erik, Briel, Matthias

“…ObjectivesComprehensive protocols are key for the planning and conduct of randomised clinical trials (RCTs). Evidence of low reporting quality of RCT protocols…”
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Rationale and design of repeated cross-sectional studies to evaluate the reporting quality of trial protocols: the Adherence to SPIrit REcommendations (ASPIRE) study and associated projects by Gryaznov, Dmitry, Odutayo, Ayodele, von Niederhäusern, Belinda, Speich, Benjamin, Kasenda, Benjamin, Ojeda-Ruiz, Elena, Blümle, Anette, Schandelmaier, Stefan, Mertz, Dominik, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Lohner, Szimonetta, Meerpohl, Joerg J, Nordmann, Alain, Klatte, Katharina, Ghosh, Nilabh, Heravi, Ala Taji, Wong, Jacqueline, Chow, Ngai, Hong, Patrick Jiho, Cord, Kimberly Mc, Sricharoenchai, Sirintip, Busse, Jason W, Agarwal, Arnav, Saccilotto, Ramon, Schwenkglenks, Matthias, Moffa, Giusi, Hemkens, Lars G, Hopewell, Sally, von Elm, Erik, Briel, Matthias

“…Clearly structured and comprehensive protocols are an essential component to ensure safety of participants, data validity, successful conduct, and credibility…”
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Early minimally invasive image-guided eNdoscopic evacuation of iNTracerebral hemorrhage: a phase II pilot trial by Hallenberger, Tim Jonas, Fischer, Urs, Ghosh, Nilabh, Kuhle, Jens, Guzman, Raphael, Bonati, Leo Hermann, Soleman, Jehuda

“…Background Whether minimally invasive endoscopic surgery (ES) improves survival and functional outcome in people with spontaneous supratentorial intracerebral…”
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Targeting compensatory MEK/ERK activation increases JAK inhibitor efficacy in myeloproliferative neoplasms by Stivala, Simona, Codilupi, Tamara, Brkic, Sime, Baerenwaldt, Anne, Ghosh, Nilabh, Hao-Shen, Hui, Dirnhofer, Stephan, Dettmer, Matthias S, Simillion, Cedric, Kaufmann, Beat A, Chiu, Sophia, Keller, Matthew, Kleppe, Maria, Hilpert, Morgane, Buser, Andreas S, Passweg, Jakob R, Radimerski, Thomas, Skoda, Radek C, Levine, Ross L, Meyer, Sara C

“…Constitutive JAK2 signaling is central to myeloproliferative neoplasm (MPN) pathogenesis and results in activation of STAT, PI3K/AKT, and MEK/ERK signaling…”
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Escape from Type II JAK2 Inhibition in MPN Depends on AXL/MAPK Activation and Is Targetable by Codilupi, Tamara, Szybinski, Jakub, Brkic, Sime, Stivala, Simona, Yang, Julie, Ghosh, Nilabh, Buczak, Katarzyna, Passweg, Jakob, Angelillo-Scherrer, Anne, Dirnhofer, Stefan, Levine, Ross L., Koche, Richard, Meyer, Sara C.

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Development of Resistance to Type II JAK2 Inhibitors in MPN Depends on AXL Kinase and Is Targetable by Codilupi, Tamara, Szybinski, Jakub, Arunasalam, Stefanie, Jungius, Sarah, Dunbar, Andrew C, Stivala, Simona, Brkic, Sime, Albrecht, Camille, Vokalova, Lenka, Yang, Julie L, Buczak, Katarzyna, Ghosh, Nilabh, Passweg, Jakob R, Rovo, Alicia, Angelillo-Scherrer, Anne, Pankov, Dmitry, Dirnhofer, Stefan, Levine, Ross L, Koche, Richard, Meyer, Sara C

“…Myeloproliferative neoplasms (MPN) dysregulate JAK2 signaling. Because clinical JAK2 inhibitors have limited disease-modifying effects, type II JAK2 inhibitors…”
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A meta-research study of randomized controlled trials found infrequent and delayed availability of protocols by Schönenberger, Christof Manuel, Griessbach, Alexandra, Taji Heravi, Ala, Gryaznov, Dmitry, Gloy, Viktoria L., Lohner, Szimonetta, Klatte, Katharina, Ghosh, Nilabh, Lee, Hopin, Mansouri, Anita, Marian, Ioana R., Saccilotto, Ramon, Nury, Edris, Busse, Jason W., von Niederhäusern, Belinda, Mertz, Dominik, Blümle, Anette, Odutayo, Ayodele, Hopewell, Sally, Speich, Benjamin, Briel, Matthias

“…Availability of randomized controlled trial (RCT) protocols is essential for the interpretation of trial results and research transparency. In this study, we…”
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Reporting quality of trial protocols improved for non-regulated interventions but not regulated interventions: A repeated cross-sectional study by Lohner, Szimonetta, Gryaznov, Dmitry, von Niederhäusern, Belinda, Speich, Benjamin, Kasenda, Benjamin, Ojeda-Ruiz, Elena, Schandelmaier, Stefan, Mertz, Dominik, Odutayo, Ayodele, Tomonaga, Yuki, Amstutz, Alain, Pauli-Magnus, Christiane, Gloy, Viktoria, Bischoff, Karin, Wollmann, Katharina, Rehner, Laura, Meerpohl, Joerg J, Nordmann, Alain, Klatte, Katharina, Ghosh, Nilabh, Heravi, Ala Taji, Wong, Jacqueline, Chow, Ngai, Hong, Patrick Jiho, McCord, Kimberly, Sricharoenchai, Sirintip, Busse, Jason W., Agarwal, Arnav, Saccilotto, Ramon, Schwenkglenks, Matthias, Moffa, Giusi, Hemkens, Lars G., Hopewell, Sally, von Elm, Erik, Blümle, Anette, Briel, Matthias

“…To investigate the adherence of randomised controlled trial (RCT) protocols evaluating non-regulated interventions (including dietary interventions, surgical…”
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Cobalt chloride-mediated protein kinase Cα (PKCα) phosphorylation induces hypoxia-inducible factor 1α (HIF1α) in the nucleus of gastric cancer cell by Rath, Suvasmita, Anand, Aditya, Ghosh, Nilabh, Das, Lopamudra, Kokate, Shrikant B., Dixit, Pragyesh, Majhi, Swetapadma, Rout, Niranjan, Singh, Shivaram P., Bhattacharyya, Asima

“…Hypoxia promotes cancer progression, and metastasis. The major protein expressed in hypoxic solid cancer is hypoxia-inducible factor 1 (HIF1). We show that…”
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Inhibition of histone/lysine acetyltransferase activity kills CoCl2-treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness by Rath, Suvasmita, Das, Lopamudra, Kokate, Shrikant Babanrao, Ghosh, Nilabh, Dixit, Pragyesh, Rout, Niranjan, Singh, Shivaram P., Chattopadhyay, Subhasis, Ashktorab, Hassan, Smoot, Duane T., Swamy, Mahadeva M., Kundu, Tapas K., Crowe, Sheila E., Bhattacharyya, Asima

“…•Invasiveness of CoCl2 or 1% O2-treated gastric cancer cell (GCC) is reduced by CTK7A.•CTK7A-mediated Noxa induction in CoCl2 and hypoxia-exposed GCC is…”
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Targeting Cell Non-Autonomous MAPK Activation As a Novel Therapeutic Strategy in Myeloproliferative Neoplasms by Meyer, Sara C., Ghosh, Nilabh, Stivala, Simona, Baerenwaldt, Anne, Hao-Shen, Hui, Dirnhofer, Stefan, Dettmer, Matthias S., Simillion, Cédric, Chiu, Sophia, Keller, Matthew, Kleppe, Maria, Hilpert, Morgane, Buser, Andreas S., Passweg, Jakob R., Radimerski, Thomas, Skoda, Radek C., Levine, Ross L.

“…Activated JAK2 signaling is a central feature of myeloproliferative neoplasm (MPN) pathogenesis, and drives myeloid blood cell production through constitutive…”
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Cobalt chloride-mediated protein kinase Cα (PKCα) phosphorylation induces hypoxia-inducible factor 1α (HIF1α) in the nucleus of gastric cancer cell by Rath, Suvasmita, Aditya Anand, Nilabh Ghosh, Lopamudra Das, Shrikant B. Kokate, Pragyesh Dixit, Swetapadma Majhi, Niranjan Rout, Shivaram P. Singh, Asima Bhattacharyya

“…Hypoxia promotes cancer progression, and metastasis. The major protein expressed in hypoxic solid cancer is hypoxia-inducible factor 1 (HIF1). We show that…”
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Reliability of Trial Information Across Registries for Trials With Multiple Registrations: A Systematic Review by Speich, Benjamin, Gloy, Viktoria L, Klatte, Katharina, Gryaznov, Dmitry, Taji Heravi, Ala, Ghosh, Nilabh, Marian, Ioana R, Lee, Hopin, Mansouri, Anita, Lohner, Szimonetta, Saccilotto, Ramon, Nury, Edris, Chan, An-Wen, Blümle, Anette, Odutayo, Ayodele, Hopewell, Sally, Briel, Matthias

“…Clinical trial registries are important for gaining an overview of ongoing research efforts and for deterring and identifying publication bias and selective…”
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Evaluation of Planned Subgroup Analysis in Protocols of Randomized Clinical Trials by Taji Heravi, Ala, Gryaznov, Dmitry, Schandelmaier, Stefan, Kasenda, Benjamin, Briel, Matthias

“…This cross-sectional study compares randomized clinical trial protocols to assess the prevalence and reporting quality of planned subgroup analyses over time…”
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Inhibition of histone/lysine acetyltransferase activity kills CoCl 2 -treated and hypoxia-exposed gastric cancer cells and reduces their invasiveness by Rath, Suvasmita, Das, Lopamudra, Kokate, Shrikant Babanrao, Ghosh, Nilabh, Dixit, Pragyesh, Rout, Niranjan, Singh, Shivaram P, Chattopadhyay, Subhasis, Ashktorab, Hassan, Smoot, Duane T, Swamy, Mahadeva M, Kundu, Tapas K, Crowe, Sheila E, Bhattacharyya, Asima

“…Hypoxia enhances immortality and metastatic properties of solid tumors. Deregulation of histone acetylation has been associated with several metastatic cancers…”
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