Search Results - "Ghosh, Balaram"
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Probing the photo- and electro-catalytic degradation mechanism of methylene blue dye over ZIF-derived ZnO
Published in Journal of hazardous materials (05-07-2019)“…[Display omitted] •ZnO was synthesized from ZIF-8 template and also by direct calcination of Zn(NO3)2.•ZnOs were investigated for photo- and electrocatalytic…”
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2
Proinflammatory role of epithelial cell–derived exosomes in allergic airway inflammation
Published in Journal of allergy and clinical immunology (01-04-2013)“…Background Exosomes are nanovesicles involved in intercellular communication. Their roles in various diseases are often contextual, depending on the cell type…”
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3
Simvastatin mediates inhibition of exosome synthesis, localization and secretion via multicomponent interventions
Published in Scientific reports (08-11-2019)“…Discovery of exosomes as modulator of cellular communication has added a new dimension to our understanding of biological processes. Exosomes influence the…”
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4
Let-7 microRNA–mediated regulation of IL-13 and allergic airway inflammation
Published in Journal of allergy and clinical immunology (01-11-2011)“…Background IL-13, a cytokine secreted by TH 2 lymphocytes and other cells, critically modulates allergic inflammation and tissue remodeling in allergic asthma…”
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5
Structure-activity relationship of human carbonic anhydrase-II inhibitors: Detailed insight for future development as anti-glaucoma agents
Published in Bioorganic chemistry (01-01-2020)“…[Display omitted] Human carbonic anhydrase-II (hCA-II) is the most dominant physiologic isoform amongst the sixteen reported hCA isoforms. Because of its high…”
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6
IL-4 promotes asymmetric dimethylarginine accumulation, oxo-nitrative stress, and hypoxic response–induced mitochondrial loss in airway epithelial cells
Published in Journal of allergy and clinical immunology (01-07-2016)“…Background Obesity is known to increase asthma risk and severity. Increased levels of asymmetric dimethylarginine (ADMA), an endogenous nitric oxide synthase…”
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7
Antagonism of mmu-mir-106a attenuates asthma features in allergic murine model
Published in Journal of applied physiology (1985) (01-08-2012)“…MicroRNAs (miRs) regulate immunological pathways in health and disease, and a number of miRs have been shown to be altered in mouse models of asthma. The…”
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8
Hyperinsulinemia adversely affects lung structure and function
Published in American journal of physiology. Lung cellular and molecular physiology (01-05-2016)“…There is limited knowledge regarding the consequences of hyperinsulinemia on the lung. Given the increasing prevalence of obesity, insulin resistance, and…”
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9
Posttranscriptional regulation of interleukin-10 expression by hsa-miR-106a
Published in Proceedings of the National Academy of Sciences - PNAS (07-04-2009)“…IL-10 is a key regulator of the immune system that critically determines health and disease. Its expression is finely tuned both at the transcriptional and…”
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10
Inhibition of stemness and EMT by taxifolin ruthenium-p-cymene complex via downregulating the SOX2 and OCT4 expression on lung cancer
Published in Arabian journal of chemistry (01-08-2023)“…Lung carcinoma is perhaps the most often reported cancer incidence throughout the world. The flavonoid metal complexes have exhibited a potential…”
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Synthesis and anti-cancer activity of 1,4-disubstituted imidazo[4,5-c]quinolines
Published in Organic & biomolecular chemistry (01-01-2016)“…The synthesis and anti-cancer activity evaluation of fused imidazoquinoline compounds is reported in this paper. Yb(OTf)3 has been utilized as a catalyst for…”
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12
Loss-of-function of inositol polyphosphate-4-phosphatase reversibly increases the severity of allergic airway inflammation
Published in Nature communications (06-06-2012)“…Inositol polyphosphate phosphatases regulate the magnitude of phosphoinositide-3 kinase signalling output. Although inositol polyphosphate-4-phosphatase is…”
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13
Metabolic Syndrome Is Associated with Increased Oxo-Nitrative Stress and Asthma-Like Changes in Lungs
Published in PloS one (22-06-2015)“…Epidemiological studies have shown an increased obesity-related risk of asthma. In support, obese mice develop airway hyperresponsiveness (AHR). However, it…”
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14
Light-controlled modulation of gene expression by chemical optoepigenetic probes
Published in Nature chemical biology (01-05-2016)“…An approach called chemo-optical modulation of epigenetically regulated transcription (COMET) combines azobenzene-based photochromic HDAC inhibitors with…”
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15
Exhaled breath condensate metabolome clusters for endotype discovery in asthma
Published in Journal of translational medicine (22-12-2017)“…Asthma is a complex, heterogeneous disorder with similar presenting symptoms but with varying underlying pathologies. Exhaled breath condensate (EBC) is a…”
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Identification of potential antiviral lead inhibitors against SARS-CoV-2 main protease: Structure-guided virtual screening, docking, ADME, and MD Simulation based approach
Published in Artificial intelligence chemistry (01-12-2023)“…The novel coronavirus disease (COVID-19) was caused by a new strain of the virus SARS-CoV-2 in December 2019 emerged as deadly pandemic that affected millions…”
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17
In vitro Antioxidant and Cytotoxic Potential of Pleurotus Mushroom and Activity-Based Correlation: a Comparative Study
Published in Journal of analytical chemistry (New York, N.Y.) (01-04-2023)“…Herein, comparative studies were conducted on different species of Pleurotus mushroom ( Pleurotus osteratus , Pleurotus eryngii , Pleurotus sajor caju ,…”
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Beneficial effects of high dose of L-arginine on airway hyperresponsiveness and airway inflammation in a murine model of asthma
Published in Journal of allergy and clinical immunology (01-03-2010)“…Background Disturbance in the delicate balance between L-arginine–metabolizing enzymes such as nitric oxide synthase (NOS) and arginase may lead to decreased…”
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Cholesterol-conjugated poly(D, L-lactide)-based micelles as a nanocarrier system for effective delivery of curcumin in cancer therapy
Published in Drug delivery (01-01-2017)“…Polymeric micelles have been widely explored preclinically as suitable delivery systems for poorly soluble chemotherapeutic drugs in cancer therapy. The…”
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Critical Analysis and Optimization of Stoichiometric Ratio of Drug-Coformer on Cocrystal Design: Molecular Docking, In Vitro and In Vivo Assessment
Published in Pharmaceuticals (Basel, Switzerland) (01-02-2023)“…In this present research, an attempt has been made to address the influence of drug-coformer stoichiometric ratio on cocrystal design and its impact on…”
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