Search Results - "Ghosh, Anil K."
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On Perfect Clustering of High Dimension, Low Sample Size Data
Published in IEEE transactions on pattern analysis and machine intelligence (01-09-2020)“…Popular clustering algorithms based on usual distance functions (e.g., the Euclidean distance) often suffer in high dimension, low sample size (HDLSS)…”
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Fighting malaria with engineered symbiotic bacteria from vector mosquitoes
Published in Proceedings of the National Academy of Sciences - PNAS (31-07-2012)“…The most vulnerable stages of Plasmodium development occur in the lumen of the mosquito midgut, a compartment shared with symbiotic bacteria. Here, we describe…”
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A nonparametric two-sample test applicable to high dimensional data
Published in Journal of multivariate analysis (01-01-2014)“…The multivariate two-sample testing problem has been well investigated in the literature, and several parametric and nonparametric methods are available for…”
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4
Plasmodium ookinetes coopt mammalian plasminogen to invade the mosquito midgut
Published in Proceedings of the National Academy of Sciences - PNAS (11-10-2011)“…Ookinete invasion of the mosquito midgut is an essential step for the development of the malaria parasite in the mosquito. Invasion involves recognition…”
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Full maturation of in vitro Plasmodium falciparum oocysts using the AlgiMatrix 3D culture system
Published in Malaria journal (20-08-2024)“…Plasmodium falciparum oocysts undergo growth and maturation in a unique setting within the mosquito midgut, firmly situated between the epithelium and the…”
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Distribution-free high-dimensional two-sample tests based on discriminating hyperplanes
Published in Test (Madrid, Spain) (01-09-2016)“…In this article, we propose a general procedure for multivariate generalizations of univariate distribution-free tests involving two independent samples as…”
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Multiple pathways for Plasmodium ookinete invasion of the mosquito midgut
Published in Proceedings of the National Academy of Sciences - PNAS (28-01-2014)“…Plasmodium ookinete invasion of the mosquito midgut is a crucial step of the parasite life cycle but little is known about the molecular mechanisms involved…”
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The Development of Whole Sporozoite Vaccines for Plasmodium falciparum Malaria
Published in Frontiers in immunology (11-12-2018)“…Each year malaria kills hundreds of thousands of people and infects hundreds of millions of people despite current control measures. An effective malaria…”
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Malaria parasite invasion of the mosquito salivary gland requires interaction between the Plasmodium TRAP and the Anopheles saglin proteins
Published in PLoS pathogens (01-01-2009)“…SM1 is a twelve-amino-acid peptide that binds tightly to the Anopheles salivary gland and inhibits its invasion by Plasmodium sporozoites. By use of…”
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Disruption of Plasmodium falciparum development by antibodies against a conserved mosquito midgut antigen
Published in Proceedings of the National Academy of Sciences - PNAS (14-08-2007)“…Malaria parasites must undergo development within mosquitoes to be transmitted to a new host. Antivector transmission-blocking vaccines inhibit parasite…”
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Some intriguing properties of Tukey's half-space depth
Published in Bernoulli : official journal of the Bernoulli Society for Mathematical Statistics and Probability (01-11-2011)“…For multivariate data, Tukey's half-space depth is one of the most popular depth functions available in the literature. It is conceptually simple and satisfies…”
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Purification and production of Plasmodium falciparum zygotes from in vitro culture using magnetic column and Percoll density gradient
Published in Malaria journal (25-05-2020)“…Plasmodium falciparum zygotes develop in the mosquito midgut after an infectious blood meal containing mature male and female gametocytes. Studies of…”
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On robust classification using projection depth
Published in Annals of the Institute of Statistical Mathematics (01-06-2012)“…This article uses projection depth (PD) for robust classification of multivariate data. Here we consider two types of classifiers, namely, the maximum depth…”
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PfCap380 as a marker for Plasmodium falciparum oocyst development in vivo and in vitro
Published in Malaria journal (02-04-2018)“…Despite the importance of the Plasmodium berghei oocyst capsule protein (PbCap380) in parasite survival, very little is known about the orthologous Plasmodium…”
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Plasmodium falciparum ookinetes require mosquito midgut chondroitin sulfate proteoglycans for cell invasion
Published in Proceedings of the National Academy of Sciences - PNAS (02-10-2007)“…Malaria transmission entails development of the Plasmodium parasite in its insect vector, the Anopheles mosquito. Parasite invasion of the mosquito midgut is…”
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Hemolytic C-type lectin CEL-III from sea cucumber expressed in transgenic mosquitoes impairs malaria parasite development
Published in PLoS pathogens (01-12-2007)“…The midgut environment of anopheline mosquitoes plays an important role in the development of the malaria parasite. Using genetic manipulation of anopheline…”
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An improved method for the in vitro differentiation of Plasmodium falciparum gametocytes into ookinetes
Published in Malaria journal (08-07-2010)“…Ookinete is the form of the malaria parasite that invades the mosquito midgut epithelium to initiate sporogony. Differentiation of ingested gametocytes into…”
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Targeting Plasmodium Ligands on Mosquito Salivary Glands and Midgut with a Phage Display Peptide Library
Published in Proceedings of the National Academy of Sciences - PNAS (06-11-2001)“…Despite vast efforts and expenditures in the past few decades, malaria continues to kill millions of persons every year, and new approaches for disease control…”
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On Exact Feature Screening in Ultrahigh-Dimensional Binary Classification
Published in Journal of computational and graphical statistics (02-04-2024)“…We propose a new model-free feature screening method based on energy distances for ultrahigh-dimensional binary classification problems. With a high…”
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On some graph-based two-sample tests for high dimension, low sample size data
Published in Machine learning (01-02-2020)“…Testing for equality of two high-dimensional distributions is a challenging problem, and this becomes even more challenging when the sample size is small. Over…”
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