Search Results - "Ghosh, Abhirupa"

Survey of drug resistance associated gene mutations in Mycobacterium tuberculosis, ESKAPE and other bacterial species by Ghosh, Abhirupa, N., Saran, Saha, Sudipto

“…Tuberculosis treatment includes broad-spectrum antibiotics such as rifampicin, streptomycin and fluoroquinolones, which are also used against other pathogenic…”
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Modulating Interleukins and their Receptors Interactions with Small Chemicals Using In Silico Approach for Asthma by Majumdar, Sreyashi, Ghosh, Abhirupa, Saha, Sudipto

“…Asthma is a complex, heterogeneous, airway inflammatory disorder broadly classified into atopic (IgE mediated) and non-atopic asthma. Monoclonal Antibodies…”
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Computational Framework for Prediction of Peptide Sequences That May Mediate Multiple Protein Interactions in Cancer-Associated Hub Proteins by Sarkar, Debasree, Patra, Piya, Ghosh, Abhirupa, Saha, Sudipto

“…A considerable proportion of protein-protein interactions (PPIs) in the cell are estimated to be mediated by very short peptide segments that approximately…”
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Regulatory role of SphK1 in TLR7/9‐dependent type I interferon response and autoimmunity by Mohammed, Sabira, Vineetha, Nalanda S., James, Shirley, Aparna, Jayasekharan S., Babu Lankadasari, Manendra, Maeda, Takahiro, Ghosh, Abhirupa, Saha, Sudipto, Li, Quan‐Zhen, Spiegel, Sarah, Harikumar, Kuzhuvelil B.

“…Plasmacytoid dendritic cells (pDCs) express Toll like receptors (TLRs) that modulate the immune response by production of type I interferons. Here, we report…”
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Identification of small molecules targeting homoserine acetyl transferase from Mycobacterium tuberculosis and Staphylococcus aureus by Chaudhary, Deepika, Singh, Avantika, Marzuki, Mardiana, Ghosh, Abhirupa, Kidwai, Saqib, Gosain, Tannu Priya, Chawla, Kiran, Gupta, Sonu Kumar, Agarwal, Nisheeth, Saha, Sudipto, Kumar, Yashwant, Thakur, Krishan Gopal, Singhal, Amit, Singh, Ramandeep

“…There is an urgent need to validate new drug targets and identify small molecules that possess activity against both drug-resistant and drug-sensitive…”
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Ydj1 interaction at nucleotide-binding-domain of yeast Ssa1 impacts Hsp90 collaboration and client maturation by Gaur, Deepika, Kumar, Navinder, Ghosh, Abhirupa, Singh, Prashant, Kumar, Pradeep, Guleria, Jyoti, Kaur, Satinderdeep, Malik, Nikhil, Saha, Sudipto, Nystrom, Thomas, Sharma, Deepak

“…Hsp90 constitutes one of the major chaperone machinery in the cell. The Hsp70 assists Hsp90 in its client maturation though the underlying basis of the Hsp70…”
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RegX3 Activates whiB3 Under Acid Stress and Subverts Lysosomal Trafficking of Mycobacterium tuberculosis in a WhiB3-Dependent Manner by Mahatha, Amar Chandra, Mal, Soumya, Majumder, Debayan, Saha, Sudipto, Ghosh, Abhirupa, Basu, Joyoti, Kundu, Manikuntala

“…Two-component systems (TCSs) are central to the ability of Mycobacterium tuberculosis to respond to stress. One such paired TCS is SenX3-RegX3, which responds…”
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Genome-wide identification and annotation of SNPs for economically important traits in Frieswal™, newly evolved crossbred cattle of India by Raja, Thiruvothur Venkatesan, Alex, Rani, Singh, Umesh, Kumar, Sushil, Das, Achintya Kumar, Sengar, Gyanendra, Singh, Amit Kumar, Ghosh, Abhirupa, Saha, Sudipto, Mitra, Abhijit

“…The Frieswal™ is a crossbred cattle evolved by ICAR-Central Institute for Research on Cattle utilizing more than 15,000 cattle maintained at more than 37…”
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PPIMpred: a web server for high-throughput screening of small molecules targeting protein–protein interaction by Jana, Tanmoy, Ghosh, Abhirupa, Das Mandal, Sukhen, Banerjee, Raja, Saha, Sudipto

“…PPIMpred is a web server that allows high-throughput screening of small molecules for targeting specific protein–protein interactions, namely Mdm2/P53,…”
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Meta-analysis of sputum microbiome studies identifies airway disease-specific taxonomic and functional signatures by Ghosh, Abhirupa, Saha, Sudipto

“…Studying taxonomic and functional signatures of respiratory microbiomes provide a better understanding of airway diseases. . Several human airway metagenomics…”
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BCSCdb: a database of biomarkers of cancer stem cells by Firdous, Shazia, Ghosh, Abhirupa, Saha, Sudipto

“…Cancer stem cells (CSCs) are a small heterogeneous population present within the tumor cells exhibiting self-renewal properties. CSCs have been demonstrated to…”
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RegX3-dependent transcriptional activation of kdpDE and repression of rv0500A are linked to potassium homeostasis in Mycobacterium tuberculosis by Bagchi, Shreya, Sharma, Arun Kumar, Ghosh, Abhirupa, Saha, Sudipto, Basu, Joyoti, Kundu, Manikuntala

“…Ionic homeostasis is essential for the survival and replication of Mycobacterium tuberculosis within its host. Low potassium ion concentrations trigger a…”
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Reg X 3‐dependent transcriptional activation of kdpDE and repression of rv0500A are linked to potassium homeostasis in Mycobacterium tuberculosis by Bagchi, Shreya, Sharma, Arun Kumar, Ghosh, Abhirupa, Saha, Sudipto, Basu, Joyoti, Kundu, Manikuntala

“…Ionic homeostasis is essential for the survival and replication of Mycobacterium tuberculosis within its host. Low potassium ion concentrations trigger a…”
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Computational approach to target USP28 for regulating Myc by Chakravorty, Debangana, Ghosh, Abhirupa, Saha, Sudipto

“…Myc is a crucial player in cellular proliferation and a known regulator of cancer pathobiology. Modulation of Myc expression targeting the Myc Protein-Protein…”
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A systems approach to decipher a role of transcription factor RegX3 in the adaptation of Mycobacterium tuberculosis to hypoxic stress by Mahatha, Amar Chandra, Banerjee, Srijon Kaushik, Ghosh, Abhirupa, Lata, Suruchi, Saha, Sudipto, Basu, Joyoti, Kundu, Manikuntala

“…Two-component systems (TCSs) are required for the ability of Mycobacterium tuberculosis to respond to stress. The paired TCS, SenX3-RegX3 is known to respond…”
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Calcimycin mediates mycobacterial killing by inducing intracellular calcium-regulated autophagy in a P2RX7 dependent manner by Mawatwal, Shradha, Behura, Assirbad, Ghosh, Abhirupa, Kidwai, Saqib, Mishra, Abtar, Deep, Amar, Agarwal, Sakshi, Saha, Sudipto, Singh, Ramandeep, Dhiman, Rohan

“…Phenotypic screening led to the identification of calcimycin as a potent inhibitor of Mycobacterium bovis BCG (M. bovis BCG) growth in vitro and in THP-1…”
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4-(Benzyloxy)phenol-induced p53 exhibits antimycobacterial response triggering phagosome-lysosome fusion through ROS-dependent intracellular Ca 2+ pathway in THP-1 cells by Naik, Lincoln, Patel, Salina, Kumar, Ashish, Ghosh, Abhirupa, Mishra, Abtar, Das, Mousumi, Nayak, Dev Kiran, Saha, Sudipto, Mishra, Amit, Singh, Ramandeep, Behura, Assirbad, Dhiman, Rohan

“…Drug-resistant tuberculosis (TB) outbreak has emerged as a global public health crisis. Therefore, new and innovative therapeutic options like host-directed…”
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4-(Benzyloxy)phenol-induced p53 exhibits antimycobacterial response triggering phagosome-lysosome fusion through ROS-dependent intracellular Ca2+ pathway in THP-1 cells by Naik, Lincoln, Patel, Salina, Kumar, Ashish, Ghosh, Abhirupa, Mishra, Abtar, Das, Mousumi, Nayak, Dev Kiran, Saha, Sudipto, Mishra, Amit, Singh, Ramandeep, Behura, Assirbad, Dhiman, Rohan

“…Drug-resistant tuberculosis (TB) outbreak has emerged as a global public health crisis. Therefore, new and innovative therapeutic options like host-directed…”
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Soybean lectin induces autophagy through P2RX7 dependent activation of NF-κB-ROS pathway to kill intracellular mycobacteria by Mishra, Abtar, Behura, Assirbad, Kumar, Ashish, Ghosh, Abhirupa, Naik, Lincoln, Mawatwal, Shradha, Mohanty, Subhashree Subhasmita, Mishra, Amit, Saha, Sudipto, Bhutia, Sujit K., Singh, Ramandeep, Dhiman, Rohan

“…Background: Host-directed therapy is considered a novel anti-tuberculosis strategy in tackling the tuberculosis burden through autophagy induction by various…”
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