Search Results - "Gholami, Shadi K"
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Editorial: The role of micronutrients in renal physiology and pathophysiology
Published in Frontiers in physiology (2023)Get full text
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Effects of Mineralocorticoid Receptor Blockade and Statins on Kidney Injury Marker 1 (KIM-1) in Female Rats Receiving L-NAME and Angiotensin II
Published in International journal of molecular sciences (30-03-2023)“…Kidney injury molecule-1 (KIM-1) is a biomarker of renal injury and a predictor of cardiovascular disease. Aldosterone, via activation of the mineralocorticoid…”
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Enhanced Thrombotic Responses Are Associated With Striatin Deficiency and Aldosterone
Published in Journal of the American Heart Association (16-11-2021)“…Background In addition to its role on blood pressure, aldosterone (ALDO) also affects the hemostatic system leading to increased experimental thrombosis…”
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Striatin Gene Variants Are Associated With Salt Sensitivity of Blood Pressure by Mechanisms That Differ in Women and Men
Published in Hypertension (Dallas, Tex. 1979) (01-02-2024)“…Salt sensitivity of blood pressure (SSBP) is a substantial risk factor for cardiovascular morbidity and mortality. Striatin (STRN) is critical for estrogen and…”
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Salt Sensitivity of Blood Pressure and Aldosterone: Interaction Between the Lysine-specific Demethylase 1 Gene, Sex, and Age
Published in The journal of clinical endocrinology and metabolism (19-04-2022)“…Salt sensitivity of blood pressure (SSBP) is associated with increased cardiovascular risk, especially in individuals of African descent, although the…”
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Biological sex modifies aldosterone’s secretion at a cellular level
Published in Journal of endocrinology (24-11-2021)“…Inconsistencies have been reported on the effect of sex on aldosterone (ALDO) levels leading to clinical confusion. The reasons for these inconsistencies are…”
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mTORC1 Deficiency Modifies Volume Homeostatic Responses to Dietary Sodium in a Sex-Specific Manner
Published in Endocrinology (Philadelphia) (01-05-2020)“…Abstract The mechanistic target of the rapamycin (mTOR) pathway plays a role in features common to both excess salt/aldosterone and cardiovascular/renal…”
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Abstract 122: Effect Of Tie2-cre Endothelial Caveolin-1 Deficiency Mice On Murine Cardiovascular And Metabolic Phenotypes
Published in Hypertension (Dallas, Tex. 1979) (01-09-2022)“…Abstract only In humans, caveolin-1 (cav-1) gene polymorphisms confer a metabolic syndrome (MetS) phenotype and higher aldosterone (Aldo) levels. Further,…”
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Abstract P140: Impact Of Ovariectomy On Aldosterone And Blood Pressure In Lysine-Specific Demethylase 1 (LSD1) Deficient Mice
Published in Hypertension (Dallas, Tex. 1979) (01-09-2023)“…Abstract only LSD1 regulates steroid receptor function including estrogen and mineralocorticoid receptor. Women of African descent who carry the LSD1 risk…”
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Abstract P228: Mineralocorticoid Receptor Antagonist And Lipophilic Statin Reduce Urinary Kidney Injury Marker 1 (Kim-1) In Female Rats Receiving L-NAME And Angiotensin II
Published in Hypertension (Dallas, Tex. 1979) (01-09-2020)“…Abstract only Statins have beneficial cardiovascular effects some of which appear to be cholesterol-independent and the mechanisms for these latter effects are…”
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