Search Results - "Gho, Y. S."

Large-scale generation of cell-derived nanovesicles by Jo, W, Kim, J, Yoon, J, Jeong, D, Cho, S, Jeong, H, Yoon, Y J, Kim, S C, Gho, Y S, Park, J

“…Exosomes are enclosed compartments that are released from cells and that can transport biological contents for the purpose of intercellular communications…”
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Staphylococcus aureus-derived extracellular vesicles induce neutrophilic pulmonary inflammation via both Th1 and Th17 cell responses by Kim, M.-R., Hong, S.-W., Choi, E.-B., Lee, W.-H., Kim, Y.-S., Jeon, S. G., Jang, M. H., Gho, Y. S., Kim, Y.-K.

“…Background Recent evidence indicates that Staphylococcus aureus, one of the most important human pathogens, secretes vesicles into the extracellular milieu…”
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Extracellular vesicles derived from Staphylococcus aureus induce atopic dermatitis-like skin inflammation by Hong, S.-W, Kim, M.-R, Lee, E.-Y, Kim, J.H, Kim, Y.-S, Jeon, S.G, Yang, J.-M, Lee, B.-J, Pyun, B.-Y, Gho, Y.S, Kim, Y.-K

“…To cite this article: Hong S-W, Kim M-R, Lee E-Y, Kim JH, Kim Y-S, Jeon SG, Yang J-M, Lee B-J, Pyun B-Y, Gho YS, Kim Y-K. Extracellular vesicles derived from…”
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TNF-alpha is a key mediator in the development of Th2 cell response to inhaled allergens induced by a viral PAMP double-stranded RNA by Choi, J.-P., Kim, Y.-S., Kim, O. Y., Kim, Y.-M., Jeon, S. G., Roh, T.-Y., Park, J.-S., Gho, Y. S., Kim, Y.-K.

“…Background Viral pathogen–associated molecular patterns, such as dsRNA, disrupt airway tolerance to inhaled allergens. Specifically, the Th2 and Th17 cell…”
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A viral PAMP double‐stranded RNA induces allergen‐specific Th17 cell response in the airways which is dependent on VEGF and IL‐6 by Choi, J.‐P., Kim, Y.‐S., Tae, Y.‐M., Choi, E.‐J., Hong, B.‐S., Jeon, S. G., Gho, Y. S., Zhu, Z., Kim, Y.‐K.

“…To cite this article: Choi J‐P, Kim Y‐S, Tae Y‐M, Choi E‐J, Hong B‐S, Jeon SG, Gho YS, Zhu Z, Kim Y‐K. A viral PAMP double‐stranded RNA induces…”
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Extracellular vesicles are key intercellular mediators in the development of immune dysfunction to allergens in the airways by Shin, T.-S, Kim, J.H, Kim, Y.-S, Jeon, S.G, Zhu, Z, Gho, Y.S, Kim, Y.-K

“…To cite this article: Shin T-S, Kim JH, Kim Y-S, Jeon SG, Zhu Z, Gho YS, Kim Y-K. Extracellular vesicles are key intercellular mediators in the development of…”
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15-lipoxygenase metabolites play an important role in the development of a T-helper type 1 allergic inflammation induced by double-stranded RNA by Jeon, S. G., Moon, H.-G., Kim, Y.-S., Choi, J.-P., Shin, T.-S., Hong, S.-W., Tae, Y.-M., Kim, S.-H., Zhu, Z., Gho, Y. S., Kim, Y.-K.

“…Summary Background We recently demonstrated that the T‐helper type 1 (Th1) immune response plays an important role in the development of non‐eosinophilic…”
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Decreased diversity of nasal microbiota and their secreted extracellular vesicles in patients with chronic rhinosinusitis based on a metagenomic analysis by Choi, E.‐B., Hong, S.‐W., Kim, D.‐K., Jeon, S. G., Kim, K.‐R., Cho, S.‐H., Gho, Y. S., Jee, Y.‐K., Kim, Y.‐K.

“…Background Chronic rhinosinusitis (CRS) is an inflammatory process in the nasal cavity and paranasal sinuses, and bacteria have been considered to be a cause…”
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Distinct association of genetic variations of vascular endothelial growth factor, transforming growth factor-β, and fibroblast growth factor receptors with atopy and airway hyperresponsiveness by Park, H.-K, Park, H.W, Jeon, S.G, Shin, E.-S, Gho, Y.S, Cho, S.-H, Kim, Y.-Y, Kim, Y.-K

“…Recent studies showed that high levels of transforming growth factor (TGF)-β1 in the airways reduced airway responsiveness, which was reversed in conditions of…”
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Association and functional relevance of E237G, a polymorphism of the high-affinity immunoglobulin E-receptor β chain gene, to airway hyper-responsiveness by Kim, Y.-K., Park, H.-W., Yang, J.-S., Oh, S.-Y., Chang, Y.-S., Shin, E.-S., Lee, J.-E., Kim, S., Gho, Y. S., Cho, S.-H., Min, K.-U., Kim, Y.-Y.

“…Summary Background The hyper‐sensitivity reaction of IgE, with its high‐affinity receptors (FcɛRI), is central to the phenomenon of atopic diseases. Objective…”
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Extracellular vesicles, especially derived from Gram-negative bacteria, in indoor dust induce neutrophilic pulmonary inflammation associated with both Th1 and Th17 cell responses by Kim, Y.-S., Choi, E.-J., Lee, W.-H., Choi, S.-J., Roh, T.-Y., Park, J., Jee, Y.-K., Zhu, Z., Koh, Y.-Y., Gho, Y. S., Kim, Y.-K.

“…Summary Background Many bacterial components in indoor dust can evoke inflammatory pulmonary diseases. Bacteria secrete nanometre‐sized vesicles into the…”
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An important role of tumor necrosis factor receptor‐2 on natural killer T cells on the development of dsRNA‐enhanced Th2 cell response to inhaled allergens by Choi, J.‐P., Kim, Y.‐M., Choi, H.‐I., Choi, S.‐J., Park, H. T., Lee, W.‐H., Gho, Y. S., Jee, Y.‐K., Jeon, S. G., Kim, Y.‐K.

“…Background Recent evidence indicates that TNF‐α is a key mediator of the development of dsRNA‐enhanced Th2 cell response to inhaled allergens. Natural killer T…”
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Endostatin Blocks Vascular Endothelial Growth Factor-mediated Signaling via Direct Interaction with KDR/Flk-1 by Kim, Young-Mi, Hwang, Sewook, Kim, Young-Myoeng, Pyun, Bo-Jeong, Kim, Tae-Yoon, Lee, Seung-Taek, Gho, Yong Song, Kwon, Young-Guen

“…Endostatin, a fragment of collagen XVIII, is a potent anti-angiogenic protein, but the molecular mechanism of its action is not yet clear. We examined the…”
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Co-accumulation of vascular endothelial growth factor with β-amyloid in the brain of patients with Alzheimer’s disease by Yang, Seung-Pil, Bae, Dong-Goo, Kang, Hyo Jung, Gwag, Byoung Joo, Gho, Yong Song, Chae, Chi-Bom

“…Alzheimer’s disease (AD) is accompanied by the progressive deposition of β-amyloid (Aβ) in both senile plaques and cerebral blood vessels, loss of central…”
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Angiogenic activity of human soluble intercellular adhesion molecule-1 by YONG SONG GHO, KLEINMAN, H. K, SOSNE, G

“…Serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) are elevated in a number of pathological conditions associated with angiogenesis, including…”
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Association between a genetic variation of CC chemokine receptor-2 and atopic asthma by Kim, Y.-K, Oh, H.-B, Lee, E.-Y, Gho, Y.S, Lee, J.-E, Kim, Y.-Y

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Capsaicin inhibits in vitro and in vivo angiogenesis by MIN, Jeong-Ki, HAN, Kyu-Yeon, KIM, Eok-Cheon, KIM, Young-Myeong, LEE, Sae-Won, KIM, Ok-Hee, KIM, Kyu-Won, YONG SONG GHO, KWON, Young-Guen

“…Capsaicin (trans-8-methyl-N-vanillyl-6-nonenamide), a natural product of Capsicum species, is known to induce excitation of nociceptive terminals involved in…”
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Stimulation of tumor growth by human soluble intercellular adhesion molecule-1 by YONG SONG GHO, KIM, Phillia N, LI, Hao-Chuan, ELKIN, Michael, KLEINMAN, Hynda K

“…Because serum levels of soluble intercellular adhesion molecule-1 (sICAM-1) are elevated in cancer and sICAM-1 is angiogenic, we tested the ability of sICAM-1…”
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1,2,3,4,6-Penta- O-galloyl-beta- d-glucose blocks endothelial cell growth and tube formation through inhibition of VEGF binding to VEGF receptor by Lee, Sung-Jin, Lee, Hwan Myung, Ji, Seung-Taek, Lee, Seung-Rock, Mar, Woongchon, Gho, Yong Song

“…Tumor angiogenesis is a critical step for the growth and metastasis of solid tumors. Vascular endothelial growth factor (VEGF) is the most important angiogenic…”
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BRAF(V600) inhibition alters the microRNA cargo in the vesicular secretome of malignant melanoma cells by Lunavat, Taral R, Cheng, L., Einarsdottir, Berglind Osk, Olofsson Bagge, Roger, Muralidharan, Somsundar Veppil, Sharples, R. A., Lässer, Cecilia, Gho, Y. S., Hill, A. F., Nilsson, Jonas A, Lötvall, Jan

“…The BRAF inhibitors vemurafenib and dabrafenib can be used to treat patients with metastatic melanomas harboring BRAF(V600) mutations. Initial antitumoral…”
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