Clinical correlates of leukoaraiosis: A study of 175 patients

Background: In India, the correlates of leukoaraiosis (LA) have not been widely reported. This study was designed to investigate the factors which correlate with LA. Materials and Methods: We included patients with LA who consented for the study and graded their severity on the basis of Fazekas scal...

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Published in:	Annals of the Indian Academy of Neurology Vol. 19; no. 4; pp. 478 - 481
Main Authors:	Wadia, Rustom, Ghiya, Sandesh, Singh, Joshita, Sontakke, Santosh, Bharadwaj, Vishwas, Sonawane, Rahul, Bade, Yogesh, Shrikanth, K, Goli, Nikhil, Chauhan, Rohit, Nadkarni, Nilesh
Format:	Journal Article
Language:	English
Published:	India Wolters Kluwer India Pvt. Ltd 01-10-2016 Medknow Publications and Media Pvt. Ltd Medknow Publications & Media Pvt. Ltd Medknow Publications & Media Pvt Ltd Wolters Kluwer Medknow Publications
Subjects:	Care and treatment Cognitive decline Diagnosis gait and sphincter disturbances leukoaraiosis Nervous system diseases Original India Cognitive decline leukoaraiosis gait and sphincter disturbances
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Summary:	Background: In India, the correlates of leukoaraiosis (LA) have not been widely reported. This study was designed to investigate the factors which correlate with LA. Materials and Methods: We included patients with LA who consented for the study and graded their severity on the basis of Fazekas scale. We excluded patients with LA who did not consent/cooperate for the study as also patients with other white matter changes which mimic LA. Results: LA is a common and under-rated cause of disability. Presentations include cognitive decline, gait disturbance, dysarthria, bladder/bowel sphincter disturbances, and increased risk of stroke. The comorbidities include hyperhomocysteinemia, hypertension, dyslipidemia, tobacco use, ischemic heart disease, previous stroke, atrial fibrillation, chronic renal failure, and bariatric surgery.
Bibliography:	ObjectType-Article-1 SourceType-Scholarly Journals-1 ObjectType-Feature-2 content type line 23
ISSN:	0972-2327 1998-3549
DOI:	10.4103/0972-2327.194425