Search Results - "Ghitza, Udi E."

Role of BDNF and GDNF in drug reward and relapse: A review by Ghitza, Udi E., Zhai, Haifeng, Wu, Ping, Airavaara, Mikko, Shaham, Yavin, Lu, Lin

“…Brain-derived neurotrophic factor (BDNF) and glial cell line-derived neurotrophic factor (GDNF) are neurotrophic factors that are critical for the growth,…”
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Overlapping Mechanisms of Stress-Induced Relapse to Opioid Use Disorder and Chronic Pain: Clinical Implications by Ghitza, Udi E

“…Over the past two decades, a steeply growing number of persons with chronic non-cancer pain have been using opioid analgesics chronically to treat it,…”
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Needed Relapse-Prevention Research on Novel Framework (ASPIRE Model) for Substance Use Disorders Treatment by Ghitza, Udi E

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Stress Impairs Reconsolidation of Drug Memory via Glucocorticoid Receptors in the Basolateral Amygdala by Wang, Xiao-Yi, Zhao, Mei, Ghitza, Udi E, Li, Yan-Qin, Lu, Lin

“…Relapse to drug taking induced by exposure to cues associated with drugs of abuse is a major challenge to the treatment of drug addiction. Previous studies…”
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Commentary: A Gene-Based Association Method for Mapping Traits Using Reference Transcriptome Data by Ghitza, Udi E

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A Commentary on "A New Initiative on Precision Medicine" by Ghitza, Udi E

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ASPIRE Model for Treating Cannabis and Other Substance Use Disorders: A Novel Personalized-Medicine Framework by Ghitza, Udi E

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Commentary: Rewriting the Valuation and Salience of Alcohol-Related Stimuli via Memory Reconsolidation by Ghitza, Udi E

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Exemplar Hospital initiation trial to Enhance Treatment Engagement (EXHIT ENTRE): protocol for CTN-0098B a randomized implementation study to support hospitals in caring for patients with opioid use disorder by Bart, Gavin, Korthuis, P Todd, Donohue, Julie M, Hagedorn, Hildi J, Gustafson, Dave H, Bazzi, Angela R, Enns, Eva, McNeely, Jennifer, Ghitza, Udi E, Magane, Kara M, Baukol, Paulette, Vena, Ashley, Harris, Jacklyn, Voronca, Delia, Saitz, Richard

“…Hospitalizations involving opioid use disorder (OUD) are increasing. Medications for opioid use disorder (MOUD) reduce mortality and acute care utilization…”
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Neurobiology of relapse to heroin and cocaine seeking: An update and clinical implications by Bossert, Jennifer M., Ghitza, Udi E., Lu, Lin, Epstein, David H., Shaham, Yavin

“…The central problem in the treatment of cocaine and heroin addiction is high rates of relapse to drug use after periods of forced or self-imposed abstinence…”
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Commentary: Interaction of the ADRB2 Gene Polymorphism with Childhood Trauma in Predicting Adult Symptoms of Posttraumatic Stress Disorder by Ghitza, Udi E

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An Examination of the Feasibility of Detecting Cocaine Use Using Smartwatches by Ertin, Emre, Sugavanam, Nithin, Holtyn, August F., Preston, Kenzie L., Bertz, Jeremiah W., Marsch, Lisa A., McLeman, Bethany, Shmueli-Blumberg, Dikla, Collins, Julia, King, Jacqueline S., McCormack, Jennifer, Ghitza, Udi E.

“…As digital technology increasingly informs clinical trials, novel ways to collect study data in the natural field setting have the potential to enhance the…”
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Multicomorbidity of chronic diseases and substance use disorders and their association with hospitalization: Results from electronic health records data by Wu, Li-Tzy, Zhu, He, Ghitza, Udi E.

“…•Comorbidities of substance use disorders (SUDs) and chronic diseases were examined.•In the sample (N = 211,880), 48.3% had at least 1 of 9 chronic conditions…”
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Brain Mu-Opioid Receptor Binding Predicts Treatment Outcome in Cocaine-Abusing Outpatients by Ghitza, Udi E, Preston, Kenzie L, Epstein, David H, Kuwabara, Hiroto, Endres, Christopher J, Bencherif, Badreddine, Boyd, Susan J, Copersino, Marc L, Frost, J. James, Gorelick, David A

“…Background Cocaine users not seeking treatment have increased regional brain mu-opioid receptor (mOR) binding that correlates with cocaine craving and tendency…”
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Coping strategies as a mediator of internet-delivered psychosocial treatment: Secondary analysis from a NIDA CTN multisite effectiveness trial by Lévesque, Annie, MD, Campbell, Aimee N.C., PhD, Pavlicova, Martina, PhD, Hu, Mei-Chen, PhD, Walker, Robrina, PhD, McClure, Erin A., PhD, Ghitza, Udi E., PhD, Bailey, Genie, MD, Stitzer, Maxine, PhD, Nunes, Edward V., MD

“…Abstract Objective. Coping strategies are a predictor of abstinence among patients with substance use disorders. However, little is known regarding the role of…”
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Persistent Cue-Evoked Activity of Accumbens Neurons after Prolonged Abstinence from Self-Administered Cocaine by Ghitza, Udi E, Fabbricatore, Anthony T, Prokopenko, Volodymyr, Pawlak, Anthony P, West, Mark O

“…Persistent neural processing of information regarding drug-predictive environmental stimuli may be involved in motivating drug abusers to engage in drug…”
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Towards detecting cocaine use using smartwatches in the NIDA clinical trials network: Design, rationale, and methodology by Holtyn, August F, Bosworth, Eugene, Marsch, Lisa A, McLeman, Bethany, Meier, Andrea, Saunders, Elizabeth C, Ertin, Emre, Ullah, Md Azim, Samiei, Shahin Alan, Hossain, Monowar, Kumar, Santosh, Preston, Kenzie L, Vahabzadeh, Massoud, Shmueli-Blumberg, Dikla, Collins, Julia, McCormack, Jennifer, Ghitza, Udi E

“…AbstractCocaine use in clinical trials is often measured via self-report, which can be inaccurate, or urine drug screens, which can be intrusive and…”
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NIDA Clinical Trials Network Common Data Elements Initiative: Advancing Big-Data Addictive-Disorders Research by Ghitza, Udi E, Gore-Langton, Robert E, Lindblad, Robert, Tai, Betty

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Bupropion and Naltrexone in Methamphetamine Use Disorder by Trivedi, Madhukar H, Walker, Robrina, Ling, Walter, dela Cruz, Adriane, Sharma, Gaurav, Carmody, Thomas, Ghitza, Udi E, Wahle, Aimee, Kim, Mora, Shores-Wilson, Kathy, Sparenborg, Steven, Coffin, Phillip, Schmitz, Joy, Wiest, Katharina, Bart, Gavin, Sonne, Susan C, Wakhlu, Sidarth, Rush, A. John, Nunes, Edward V, Shoptaw, Steven

“…In a randomized trial involving participants with methamphetamine use disorder, the response among those who received bupropion and naltrexone was 11…”
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Repurposing ketamine to treat cocaine use disorder: integration of artificial intelligence‐based prediction, expert evaluation, clinical corroboration and mechanism of action analyses by Gao, Zhenxiang, Winhusen, T. John, Gorenflo, Maria, Ghitza, Udi E., Davis, Pamela B., Kaelber, David C., Xu, Rong

“…Background and aims Cocaine use disorder (CUD) is a significant public health issue for which there is no Food and Drug Administration (FDA) approved…”
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