Search Results - "Ghini, A A"
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Synthesis and activity evaluation of a series of cholanamides as modulators of the liver X receptors
Published in Bioorganic & medicinal chemistry (01-03-2018)“…[Display omitted] •A series of cholanamides with modified A/B rings were synthesized.•6β,19-Epoxycholanamide 4 was an LXRα selective…”
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2
Effect of synthetic steroids on GABAA receptor binding in rat brain
Published in Neuroscience (02-04-2015)“…Highlights • GABAA receptor binding was tested using synthetic steroids with A/B ring low flexibility. • Three ligands for specific binding sites were tested…”
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3
Long-term clinical follow-up of the multicentre, randomized study to test immunosuppressive therapy with oral prednisone for the prevention of restenosis after percutaneous coronary interventions: Cortisone plus BMS or DES veRsus BMS alone to EliminAte Restenosis (CEREA-DES)
Published in European heart journal (01-06-2013)“…To analyse the clinical outcome at 4 years in patients with coronary artery disease treated with bare metal stents (BMS) vs. BMS and oral prednisone, or…”
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4
Unstable angina and elevated C-reactive protein levels predict enhanced vasoreactivity of the culprit lesion
Published in Circulation (New York, N.Y.) (25-09-2001)“…Because plaque inflammation may modulate coronary vasomotion, the association between systemic levels of C-reactive protein (CRP) and coronary vasoreactivity…”
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5
A comparison of coronary artery stenting with angioplasty for isolated stenosis of the proximal left anterior descending coronary artery: five year clinical follow up
Published in Heart (British Cardiac Society) (01-06-2004)“…Background: Stent implantation for isolated stenosis of the proximal left anterior descending coronary artery (LAD) with preserved left ventricular function…”
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6
Coronary artery stent placement in patients with variant angina refractory to medical treatment
Published in The American journal of cardiology (01-07-1999)“…We performed a prospective study to establish the efficacy of coronary stent placement in a highly selected group of patients with focal coronary artery spasm…”
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7
Synthesis of 6,19-Sulfamidate Bridged Pregnanes
Published in Journal of organic chemistry (14-10-2005)“…Conformationally restrained substituted pregnane-20-one derivatives were obtained by an intramolecular nitrene addition onto a C-5/C-6 double bond involving a…”
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8
Effects of naloxone on myocardial ischemic preconditioning in humans
Published in Journal of the American College of Cardiology (01-06-1999)“…OBJECTIVES We attempted to establish whether naloxone, an opioid receptor antagonist, abolishes the adaptation to ischemia observed in humans during coronary…”
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9
6,19-carbon-bridged steroids. Synthesis of 6,19-methanoprogesterone
Published in Organic & biomolecular chemistry (21-03-2003)“…6,19-Methanoprogesterone (4) was synthesized in nine steps from the readily available 3 beta,20 beta-diacetyloxy-5 alpha-bromo-6,19-oxidopregnane (5) in 14%…”
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10
Differential Recruitment of Tetratricorpeptide Repeat Domain Immunophilins to the Mineralocorticoid Receptor Influences both Heat-Shock Protein 90-Dependent Retrotransport and Hormone-Dependent Transcriptional Activity
Published in Biochemistry (Easton) (11-12-2007)“…The mineralocorticoid receptor (MR) forms oligomers with the heat-shock protein 90 (Hsp90) -based heterocomplex, which contains tetratricopeptide repeat (TPR)…”
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11
Mechanisms of the warm-up phenomenon
Published in European heart journal (01-07-1996)“…The warm-up phenomenon, described in patients with coronary artery disease, refers to the improved performance following a first exercise test. The aim of this…”
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12
Effects of K(ATP) channel blockade by glibenclamide on the warm-up phenomenon
Published in European heart journal (01-02-1999)“…The increased tolerance to myocardial ischaemia observed during the second of two sequential exercise tests, i.e. the warm-up phenomenon, has been proposed as…”
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13
Influence of slow coronary blood flow on stenosis morphology
Published in Heart (British Cardiac Society) (01-08-2001)Get full text
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14
Exercise induced myocardial ischaemia does not cause increase in C-reactive protein concentration
Published in Heart (British Cardiac Society) (01-12-2000)“…[...]persistently raised plasma concentrations of CRP after coronary surgery have been shown to be predictive of postoperative complications, and in patients…”
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15
Phentolamine prevents adaptation to ischemia during coronary angioplasty : Role of α-adrenergic receptors in ischemic preconditioning
Published in Circulation (New York, N.Y.) (07-10-1997)“…Experimental studies indicate that alpha-adrenergic receptors are involved in ischemic preconditioning. Their role in humans is unknown. Eighteen patients…”
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16
Sodium-retaining activity of some natural and synthetic 21-deoxysteroids
Published in Molecular pharmacology (01-03-1995)“…The effect of progesterone and six other C21-deoxysteroids on renal sodium retention by male adrenalectomized rats was compared with the effect exerted by the…”
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17
Synthesis of D-Homo Analogs of Neurosteroids
Published in Molecules (Basel, Switzerland) (01-03-2000)“…17(13→18)-Abeo and D-homo analogs of the natural neurosteroid 3α-hydroxy-5αH-pregnan-20-one were prepared by anionic or radical (mercury (II) hydride mediated)…”
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18
Exercise-induced myocardial ischemia triggers the early phase of preconditioning but not the late phase
Published in The American journal of cardiology (15-02-1999)“…The aim of the present study was to establish whether exercise-induced ischemia triggers the second window of protection in 15 patients with coronary artery…”
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19
Neuroprotective action of synthetic steroids with oxygen bridge. Activity on GABAA receptor
Published in Experimental neurology (01-11-2013)“…Allopregnanolone (A) and pregnanolone (P) are able to modify neural activities acting through the GABAA receptor complex. This capacity makes them useful as…”
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20
Synthesis and GABA A receptor activity of 6-oxa-analogs of neurosteroids
Published in Steroids (01-06-2000)“…The 6-oxasteroids 3α-hydroxy-6-oxa-5α-pregnan-20-one ( 3) and 3α-hydroxy-6-oxa-5β-pregnan-20-one ( 4) were obtained from pregnenolone acetate via the…”
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