Search Results - "Ghilli, Matteo"

Molecular Mechanisms, Biomarkers and Emerging Therapies for Chemotherapy Resistant TNBC by Ferrari, Paola, Scatena, Cristian, Ghilli, Matteo, Bargagna, Irene, Lorenzini, Giulia, Nicolini, Andrea

“…Triple-negative breast cancer (TNBC) is associated with high recurrence rates, high incidence of distant metastases, and poor overall survival (OS). Taxane and…”
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Androgen receptor expression inversely correlates with histological grade and N stage in ER+/PgRlow male breast cancer by Scatena, Cristian, Scarpitta, Rosa, Innocenti, Lorenzo, Miccoli, Mario, Biancotti, Rachele, Diodati, Lucrezia, Ghilli, Matteo, Naccarato, Antonio Giuseppe

“…Purpose Androgen Receptor (AR) positivity is often displayed in breast cancer and especially in Male Breast Cancer (MBC), where it appears to be a…”
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Doxycycline, an Inhibitor of Mitochondrial Biogenesis, Effectively Reduces Cancer Stem Cells (CSCs) in Early Breast Cancer Patients: A Clinical Pilot Study by Scatena, Cristian, Roncella, Manuela, Di Paolo, Antonello, Aretini, Paolo, Menicagli, Michele, Fanelli, Giovanni, Marini, Carolina, Mazzanti, Chiara Maria, Ghilli, Matteo, Sotgia, Federica, Lisanti, Michael P, Naccarato, Antonio Giuseppe

“…Cancer stem cells (CSCs) have been implicated in tumor initiation, recurrence, metastatic spread and poor survival in multiple tumor types, breast cancers…”
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The BRCA1 c.4096+1G>A Is a Founder Variant Which Originated in Ancient Times by Aretini, Paolo, Presciuttini, Silvano, Pastore, Aldo, Galli, Alvaro, Panepinto, Sara, Tancredi, Mariella, Ghilli, Matteo, Guglielmi, Chiara, Sidoti, Diletta, Congregati, Caterina, Caligo, Maria Adelaide

“…Approximately 30–50% of hereditary breast and ovarian cancer (HBOC) is due to the presence of germline pathogenic variants in the BRCA1 (OMIM 113705) and BRCA2…”
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Development of a novel nomogram-based online tool to predict axillary status after neoadjuvant chemotherapy in cN+ breast cancer: A multicentre study on 1,950 patients by Corsi, Fabio, Albasini, Sara, Sorrentino, Luca, Armatura, Giulia, Carolla, Claudia, Chiappa, Corrado, Combi, Francesca, Curcio, Annalisa, Della Valle, Angelica, Ferrari, Guglielmo, Gasparri, Maria Luisa, Gentilini, Oreste, Ghilli, Matteo, Listorti, Chiara, Mancini, Stefano, Marinello, Peter, Meani, Francesco, Mele, Simone, Pertusati, Anna, Roncella, Manuela, Rovera, Francesca, Sgarella, Adele, Tazzioli, Giovanni, Tognali, Daniela, Folli, Secondo

“…Type of axillary surgery in breast cancer (BC) patients who convert from cN + to ycN0 after neoadjuvant chemotherapy (NAC) is still debated. The aim of the…”
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Systematic and continuous collection of patient-reported outcomes and experience in women with cancer undergoing mastectomy and immediate breast reconstruction: a study protocol for the Tuscany Region (Italy) by Ferrè, Francesca, De Rosis, Sabina, Murante, Anna Maria, Gilmore, Kendall Jamieson, Ghilli, Matteo, Mariniello, Donatella, Nuti, Sabina, Roncella, Manuela

“…IntroductionMonitoring how patients feel and what they experience during the care process gives health professionals data to improve the quality of care, and…”
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Management of the axilla in breast cancer patients: critical review, regional modified Delphi consensus and implementation in the Tuscan breast network by Ghilli, Matteo, Becherini, Carlotta, Meattini, Icro, Angiolini, Catia, Bengala, Carmelo, Marconi, Aroldo, Galli, Lorenzo, Angiolucci, Giovanni, Coltelli, Luigi, Borghesi, Simona, Lastrucci, Luciana, Manca, Gianpiero, Bianchi, Simonetta, Doria, Morena, Casella, Donato, Marotti, Lorenza, Amunni, Gianni, Roncella, Manuela

“…Purpose Data from recently trials have provided practice-changing recommendations in management of the axilla in early breast cancer (eBC). However, further…”
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Cell-free biomimetic polyurethane-based scaffold for breast reconstruction following non-malignant lesion resection. A first-in-human study by Mariniello, Maria Donatella, Ghilli, Matteo, Favati, Benedetta, Gerges, Irini, Colizzi, Livio, Tamplenizza, Margherita, Tocchio, Alessandro, Martello, Federico, Ghilardi, Maria, Cossu, Maria Cristina, Danti, Serena, Roncella, Manuela

“…Background Based on the volume of tissue removed, conservative surgery (BCS) cannot always guarantee satisfactory cosmetic results, unless resorting to more…”
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Wearable AR and 3D Ultrasound: Towards a Novel Way to Guide Surgical Dissections by Cattari, Nadia, Condino, Sara, Cutolo, Fabrizio, Ghilli, Matteo, Ferrari, Mauro, Ferrari, Vincenzo

“…Nowadays, ultrasound (US) is increasingly being chosen as imaging modality for both diagnostic and interventional applications, owing to its positive…”
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Detection of Germline Variants in 450 Breast/Ovarian Cancer Families with a Multi-Gene Panel Including Coding and Regulatory Regions by Guglielmi, Chiara, Scarpitta, Rosa, Gambino, Gaetana, Conti, Eleonora, Bellè, Francesca, Tancredi, Mariella, Cervelli, Tiziana, Falaschi, Elisabetta, Cosini, Cinzia, Aretini, Paolo, Congregati, Caterina, Marino, Marco, Patruno, Margherita, Pilato, Brunella, Spina, Francesca, Balestrino, Luisa, Tenedini, Elena, Carnevali, Ileana, Cortesi, Laura, Tagliafico, Enrico, Tibiletti, Maria Grazia, Tommasi, Stefania, Ghilli, Matteo, Vivanet, Caterina, Galli, Alvaro, Caligo, Maria Adelaide

“…With the progress of sequencing technologies, an ever-increasing number of variants of unknown functional and clinical significance (VUS) have been identified…”
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Low neutrophil-to-lymphocyte ratio and pan-immune-inflammation-value predict nodal pathologic complete response in 1274 breast cancer patients treated with neoadjuvant chemotherapy: a multicenter analysis by Gasparri, Maria Luisa, Albasini, Sara, Truffi, Marta, Favilla, Karin, Tagliaferri, Barbara, Piccotti, Francesca, Bossi, Daniela, Armatura, Giulia, Calcinotto, Arianna, Chiappa, Corrado, Combi, Francesca, Curcio, Annalisa, Della Valle, Angelica, Ferrari, Guglielmo, Folli, Secondo, Ghilli, Matteo, Listorti, Chiara, Mancini, Stefano, Marinello, Peter, Mele, Simone, Pertusati, Anna, Roncella, Manuela, Rossi, Lorenzo, Rovera, Francesca, Segattini, Silvia, Sgarella, Adele, Tognali, Daniela, Corsi, Fabio

“…Background: Systemic inflammatory markers draw great interest as potential blood-based prognostic factors in several oncological settings. Objectives: The aim…”
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Catching and monitoring clinical innovation through performance indicators. The case of the breast-conserving surgery indicator by Murante, Anna Maria, Candelori, Silvio, Rucci, Paola, Nuti, Sabina, Roncella, Manuela, Ghilli, Matteo, Mercatelli, Andrea, Fantini, Maria Pia

“…The evolution in the surgical and diagnostic procedures, the attention to women's preferences, the case mix, and differences in professional practices may lead…”
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Postural alterations in breast cancer survivors: proposal of the PABS evaluation protocol based on a systematic review by DORO, Elisa, AZZOLLINI, Valentina, GHILLI, Matteo, RONCELLA, Manuela, CHISARI, Carmelo

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Overexpression of TK1 and CDK9 in plasma-derived exosomes is associated with clinical resistance to CDK4/6 inhibitors in metastatic breast cancer patients by Del Re, Marzia, Bertolini, Ilaria, Crucitta, Stefania, Fontanelli, Lorenzo, Rofi, Eleonora, De Angelis, Claudia, Diodati, Lucrezia, Cavallero, Diletta, Gianfilippo, Giulia, Salvadori, Barbara, Fogli, Stefano, Falcone, Alfredo, Scatena, Cristian, Naccarato, Antonio Giuseppe, Roncella, Manuela, Ghilli, Matteo, Morganti, Riccardo, Fontana, Andrea, Danesi, Romano

“…Purpose Cyclin-dependent kinase 4/6 inhibitors (CDK4/6i) improve progression-free survival (PFS) in patients with hormone receptor-positive (HR+) advanced…”
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Preservation of Axillary Lymph Nodes Compared with Complete Dissection in T1–2 Breast Cancer Patients Presenting One or Two Metastatic Sentinel Lymph Nodes: The SINODAR-ONE Multicenter Randomized Clinical Trial by Tinterri, Corrado, Gentile, Damiano, Gatzemeier, Wolfgang, Sagona, Andrea, Barbieri, Erika, Testori, Alberto, Errico, Valentina, Bottini, Alberto, Marrazzo, Emilia, Dani, Carla, Dozin, Beatrice, Boni, Luca, Bruzzi, Paolo, Fernandes, Bethania, Franceschini, Davide, Spoto, Ruggero, Torrisi, Rosalba, Scorsetti, Marta, Santoro, Armando, Canavese, Giuseppe

“…Background The SINODAR-ONE trial is a prospective noninferiority multicenter randomized study aimed at assessing the role of axillary lymph node dissection…”
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Androgen receptor expression inversely correlates with histological grade and N stage in ER.sup.+/PgR.sup.low male breast cancer by Scatena, Cristian, Scarpitta, Rosa, Innocenti, Lorenzo, Miccoli, Mario, Biancotti, Rachele, Diodati, Lucrezia, Ghilli, Matteo

“…Purpose Androgen Receptor (AR) positivity is often displayed in breast cancer and especially in Male Breast Cancer (MBC), where it appears to be a…”
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PI3K mutations detected in liquid biopsy are associated to reduced sensitivity to CDK4/6 inhibitors in metastatic breast cancer patients by Del Re, Marzia, Crucitta, Stefania, Lorenzini, Giulia, De Angelis, Claudia, Diodati, Lucrezia, Cavallero, Diletta, Bargagna, Irene, Cinacchi, Paola, Fratini, Beatrice, Salvadori, Barbara, Ghilli, Matteo, Roncella, Manuela, Fontana, Andrea, Danesi, Romano, Cucchiara, Federico

“…[Display omitted] •Predictive biomarkers of resistance to CDK4/6 inhibitors are not yet available for patients’ selection.•PI3K mutations correlate with a…”
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The IBRCA1/I c.4096+1GA Is a Founder Variant Which Originated in Ancient Times by Aretini, Paolo, Presciuttini, Silvano, Pastore, Aldo, Galli, Alvaro, Panepinto, Sara, Tancredi, Mariella, Ghilli, Matteo, Guglielmi, Chiara, Sidoti, Diletta, Congregati, Caterina, Caligo, Maria Adelaide

“…Approximately 30–50% of hereditary breast and ovarian cancer (HBOC) is due to the presence of germline pathogenic variants in the BRCA1 (OMIM 113705) and BRCA2…”
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Prospective study on Oncotype DX® assay to assess recurrence risk in early ER-positive HER2-negative breast cancer patients with uncertain biological behavior by standard parameters and its impact on treatment recommendation: The POST trial by Livraghi, Luca, Martella, Francesca, Ghilli, Matteo, Angiolini, Catia, Magnanini, Simonetta, Moretti, Erica, Bengala, Carmelo, Risi, Emanuela, Molinara, Elena, Pazzagli, Ilaria, Malorni, Luca, Donati, Sara, Gabellini, Stefano, Martignetti, Angelo, Giannessi, Piergiorgio, Sanna, Giuseppina, Barellini, Leonardo, Biagioni, Chiara, Boni, Luca, Bianchi, Simonetta, Roncella, Manuela, Biganzoli, Laura

“…Data published in 2015 showed that patients with early breast cancer (EBC) and a low-risk (LR) Recurrence Score® (RS) result by the 21-gene Oncotype DX® assay…”
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Breast conserving surgery after primary systemic treatment: where we are? Update of the literature and revision of the experience of a certified breast centre in Italy by Ghilli, Matteo, Fontana, Andrea, Cantarella, Martina, Scatena, Cristian, Mazzotta, Dionisia, Li, Alessandro Quattrini, Baldetti, Gianni, Rossetti, Elena, valeria Camilleri, Coletti, Laura, Nicoli, Alice, Ghilardi, Maria, Mariniello, Donatella, Esposito, Antonella, Notarstefano, Chiara, Roncella, Manuela

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