Search Results - "Ghilardi, Stefania"
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Macrophage Phenotyping in Atherosclerosis by Proteomics
Published in International journal of molecular sciences (30-01-2023)“…Macrophages are heterogeneous and plastic cells, able to adapt their phenotype and functions to changes in the microenvironment. They are involved in several…”
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Immature Surfactant Protein B Increases in the Serum of Patients with Calcific Severe Aortic Stenosis
Published in International journal of molecular sciences (01-06-2024)“…Valvular disease is a complex pathological condition that impacts countless individuals around the globe. Due to limited treatments, it is crucial to…”
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Immature Surfactant Protein Type B and Surfactant Protein Type D Correlate with Coronary Heart Disease in Patients with Type 2 Diabetes
Published in Life (Basel, Switzerland) (17-07-2024)“…Different specific surfactant proteins (SPs) have been associated with various pathological conditions, not only of the respiratory system, but also more…”
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Symptomatic post COVID patients have impaired alveolar capillary membrane function and high VE/VCO2
Published in Respiratory research (08-02-2024)“…Abstract Background Post COVID-19 syndrome is characterized by several cardiorespiratory symptoms but the origin of patients’ reported symptomatology is still…”
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Proteome profiling identifies circulating biomarkers associated with hepatic steatosis in subjects with Prader-Willi syndrome
Published in Frontiers in endocrinology (Lausanne) (15-11-2023)“…Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by loss of expression of paternal chromosome 15q11.2-q13 genes. Individuals with PWS…”
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Surfactant-derived proteins as markers of alveolar membrane damage in heart failure
Published in PloS one (16-12-2014)“…In heart failure (HF) alveolar-capillary membrane is abnormal. Surfactant-derived proteins (SPs) and plasma receptor for advanced-glycation-end-products (RAGE)…”
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Albumin Thiolation and Oxidative Stress Status in Patients with Aortic Valve Stenosis
Published in Biomolecules (Basel, Switzerland) (28-11-2023)“…Recent evidence indicates that reactive oxygen species play an important causative role in the onset and progression of valvular diseases. Here, we analyzed…”
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Prenylcysteine Oxidase 1 Is a Key Regulator of Adipogenesis
Published in Antioxidants (21-02-2023)“…The process of adipogenesis involves the differentiation of preadipocytes into mature adipocytes. Excessive adipogenesis promotes obesity, a condition that…”
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Impact of Sacubitril/Valsartan on Circulating microRNA in Patients with Heart Failure
Published in Biomedicines (28-03-2023)“…Sacubitril/Valsartan, used for the treatment of heart failure (HF), is a combination of two drugs, an angiotensin receptor inhibitor, and a neprilysin…”
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Impact of Sacubitril/Valsartan on surfactant binding proteins, central sleep apneas, lung function tests and heart failure biomarkers: Hemodynamic or pleiotropism?
Published in Frontiers in cardiovascular medicine (15-09-2022)“…Purpose Little is known about the mechanism underlying Sacubitril/Valsartan effects in patients with heart failure (HFrEF). Aim of the study is to assess…”
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Data for proteomic analysis of murine cardiomyocytic HL-1 cells treated with siRNA against tissue factor
Published in Data in brief (01-06-2015)“…This data article is related to the research article entitled Proteomics of Tissue Factor silencing in cardiomyocytic cells reveals a new role for this…”
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Corrigendum to “Data for proteomic analysis of murine cardiomyocytic HL-1 cells treated with siRNA against tissue factor” [Data Brief 3 (2015) 117–119]
Published in Data in brief (01-12-2015)“…[This corrects the article DOI: 10.1016/j.dib.2015.02.005.]…”
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Identification of DKK-1 as a novel mediator of statin effects in human endothelial cells
Published in Scientific reports (12-11-2018)“…This study shows that DKK-1, a member of the Dickkopf family and a regulator of the Wnt pathways, represents a novel target of statins which, through the…”
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Surfactant proteins changes after acute hemodynamic improvement in patients with advanced chronic heart failure treated with Levosimendan
Published in Respiratory physiology & neurobiology (01-06-2018)“…•Levosimendan improves cardiopulmonary hemodynamics and reduces lung fluids in HF.•BNP levels and cardiopulmonary exercise test parameters improved after…”
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Circulating Factors as Potential Biomarkers of Cardiovascular Damage Progression Associated with Type 2 Diabetes
Published in Proteomes (11-10-2024)“…: Diabetes, particularly type 2 diabetes (T2D), is linked with an increased risk of developing coronary heart disease (CHD). The present study aimed to…”
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Characterization of Circulating Protein Profiles in Individuals with Prader-Willi Syndrome and Individuals with Non-Syndromic Obesity
Published in Journal of clinical medicine (25-09-2024)“…Prader-Willi syndrome (PWS) is a rare genetic disorder characterized by distinctive physical, cognitive, and behavioral manifestations, coupled with profound…”
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Surfactant derived protein type B: a new biomarker linked to respiratory failure and lung damage in mild to moderate SARS-CoV-2 pneumonia
Published in ERJ open research (22-08-2024)“…Background The COVID-19 pandemic has led to significant concern due to its impact on human health, particularly through pneumonia-induced lung damage…”
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Normal human mitral valve proteome: A preliminary investigation by gel-based and gel-free proteomic approaches
Published in Electrophoresis (01-10-2016)“…The mitral valve is a highly complex structure which regulates blood flow from the left atrium to the left ventricle (LV) avoiding a significant forward…”
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Atorvastatin reduces long pentraxin 3 expression in vascular cells by inhibiting protein geranylgeranylation
Published in Vascular pharmacology (01-04-2015)“…Abstract Background The long pentraxin PTX3 is an acute-phase multi-functional protein that might play both positive and detrimental effects under different…”
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Plasma immature form of surfactant protein type B correlates with prognosis in patients with chronic heart failure. A pilot single-center prospective study
Published in International journal of cardiology (15-12-2015)“…Abstract Background Gas exchange abnormalities are part of the heart failure (HF) syndrome and growing interest raised on possible biomarkers of…”
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