Search Results - "Ghigo, D."

The Role of Iron Impurities in the Toxic Effects Exerted by Short Multiwalled Carbon Nanotubes (MWCNT) in Murine Alveolar Macrophages by Aldieri, E., Fenoglio, I., Cesano, F., Gazzano, E., Gulino, G., Scarano, D., Attanasio, A., Mazzucco, G., Ghigo, D., Fubini, B.

“…Lung toxicity mediated by multiwalled carbon nanotubes (MWCNT) has been widely demonstrated and recently associated with induction of carcinogenic…”
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Fluoride effects: the two faces of janus by Gazzano, E, Bergandi, L, Riganti, C, Aldieri, E, Doublier, S, Costamagna, C, Bosia, A, Ghigo, D

“…The behavior of fluoride ions in the human organism is a classic example of double-edged sword. On the one hand the daily supplementation with fluoride is…”
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Artemisinin induces doxorubicin resistance in human colon cancer cells via calcium‐dependent activation of HIF‐1α and P‐glycoprotein overexpression by Riganti, C, Doublier, S, Viarisio, D, Miraglia, E, Pescarmona, G, Ghigo, D, Bosia, A

“…Background and purpose:  Artemisinin is an antimalarial drug exerting pleiotropic effects, such as the inhibition of the transcription factor nuclear…”
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Pleiotropic effects of cardioactive glycosides by Riganti, C, Campia, I, Kopecka, J, Gazzano, E, Doublier, S, Aldieri, E, Bosia, A, Ghigo, D

“…Cardioactive glycosides, like digoxin, ouabain and related compounds, are drugs that inhibit Na(+)/K(+)-ATPase and have a strong inotropic effect on heart:…”
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The association of statins plus LDL receptor‐targeted liposome‐encapsulated doxorubicin increases in vitro drug delivery across blood–brain barrier cells by Pinzón‐Daza, ML, Garzón, R, Couraud, PO, Romero, IA, Weksler, B, Ghigo, D, Bosia, A, Riganti, C

“…BACKGROUND AND PURPOSE The passage of drugs across the blood–brain barrier (BBB) limits the efficacy of chemotherapy in brain tumours. For instance, the…”
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Geranylgeraniol prevents the cytotoxic effects of mevastatin in THP‐1 cells, without decreasing the beneficial effects on cholesterol synthesis by Campia, I, Lussiana, C, Pescarmona, G, Ghigo, D, Bosia, A, Riganti, C

“…Background and purpose:  Statins, inhibitors of hydroxymethylglutaryl‐CoA reductase, reduce the intracellular synthesis of cholesterol and prevent the onset of…”
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The NADPH oxidase inhibitor apocynin (acetovanillone) induces oxidative stress by Riganti, Chiara, Costamagna, Costanzo, Bosia, Amalia, Ghigo, Dario

“…Apocynin (acetovanillone) is often used as a specific inhibitor of NADPH oxidase. In N11 glial cells, apocynin induced, in a dose-dependent way, a significant…”
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Digoxin and ouabain increase the synthesis of cholesterol in human liver cells by Campia, I, Gazzano, E, Pescarmona, G, Ghigo, D, Bosia, A, Riganti, C

“…Digoxin and ouabain are steroid drugs that inhibit the Na⁺/K⁺-ATPase, and are widely used in the treatment of heart diseases. They may also have additional…”
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Effects of TiO2-containing phosphate glasses on solubility and in vitro biocompatibility by Novajra, G., Vitale-Brovarone, C., Knowles, J. C., Maina, G., Aina, V., Ghigo, D., Bergandi, L.

“…Phosphate‐based glasses with different amounts of titanium dioxide (TiO2), having the following molar composition 50P2O5‐30CaO‐9Na2O‐3SiO2‐3MgO‐(5‐x)K2O‐xTiO2,…”
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Insulin Stimulates Glucose Transport Via Nitric Oxide/Cyclic GMP Pathway in Human Vascular Smooth Muscle Cells by Bergandi, L, Silvagno, F, Russo, I, Riganti, C, Anfossi, G, Aldieri, E, Ghigo, D, Trovati, M, Bosia, A

“…OBJECTIVE—In cultured human vascular smooth muscle cells, insulin increases cyclic GMP production by inducing nitric oxide (NO) synthesis. The aim of the…”
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Asbestos induces doxorubicin resistance in MM98 mesothelioma cells via HIF-1α by RIGANTI, C, DOUBLIER, S, ALDIERI, E, ORECCHIA, S, BETTA, P. G, GAZZANO, E, GHIGO, D, BOSIA, A

“…Human malignant mesothelioma (HMM), which is strongly related to asbestos exposure, exhibits high resistance to many anticancer drugs. Asbestos fibre…”
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Green Bank Telescope Measurement of the Systemic Velocity of the Double Pulsar Binary J0737–3039 and Implications for Its Formation by Ransom, S. M, Kaspi, V. M, Ramachandran, R, Demorest, P, Backer, D. C, Pfahl, E. D, Ghigo, F. D, Kaplan, D. L

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Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3', 5'-cyclic monophosphate and adenosine-3', 5'-cyclic monophosphate by Trovati, M., Anfossi, G., Massucco, P., Mattiello, L., Costamagna, C., Piretto, V., Mularoni, E., Cavalot, F., Bosia, A., Ghigo, D.

“…Insulin stimulates nitric oxide synthesis in human platelets and, through nitric oxide, increases platelet concentrations of both guanosine-3', 5'-cyclic…”
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Mercury's moment of inertia from spin and gravity data by Margot, Jean-Luc, Peale, Stanton J., Solomon, Sean C., Hauck II, Steven A., Ghigo, Frank D., Jurgens, Raymond F., Yseboodt, Marie, Giorgini, Jon D., Padovan, Sebastiano, Campbell, Donald B.

“…Earth‐based radar observations of the spin state of Mercury at 35 epochs between 2002 and 2012 reveal that its spin axis is tilted by (2.04 ± 0.08) arc min…”
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Ultra high molecular weight polyethylene is cytotoxic and causes oxidative stress, even when modified by Gazzano, E, Bracco, P, Bistolfi, A, Aldieri, E, Ghigo, D, Boffano, M, Costa, L, Brach Del Prever, E

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Spin State and Moment of Inertia of Venus by Margot, Jean-Luc, Campbell, Donald B, Giorgini, Jon D, Jao, Joseph S, Snedeker, Lawrence G, Ghigo, Frank D, Bonsall, Amber

“…Fundamental properties of the planet Venus, such as its internal mass dis-tribution and variations in length of day, have remained unknown. We usedEarth-based…”
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Signaling Pathway of Nitric Oxide-Induced Acrosome Reaction in Human Spermatozoa by REVELLI, Alberto, COSTAMAGNA, Costanzo, MOFFA, Federica, ALDIERI, Elisabetta, OCHETTI, Simona, BOSIA, Amalia, MASSOBRIO, Marco, LINDBLOM, Bo, GHIGO, Dario

“…Nitric oxide (NO) has been recently shown to modulate in vitro motility, viability, the acrosome reaction (AR), and metabolism of spermatozoa in various…”
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Human vascular smooth muscle cells express a constitutive nitric oxide synthase that insulin rapidly activates, thus increasing guanosine 3' :5'-cyclic monophosphate and adenosine 3' :5'-cyclic monophosphate concentrations by TROVATI, M, MASSUCCO, P, MATTIELLO, L, COSTAMAGNA, C, ALDIERI, E, CAVALOT, F, ANFOSSI, G, BOSIA, A, GHIGO, D

“…Insulin incubation of human vascular smooth muscle cells (hVSMC) for 120 min increases both guanosine 3':5'-cyclic monophosphate (cGMP) and adenosine…”
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Light Curves and Radio Structure of the 1999 September Transient Event in V4641 Sagittarii (=XTE J1819–254=SAX J1819.3–2525) by Hjellming, R. M, Rupen, M. P, Hunstead, R. W, Campbell-Wilson, D, Mioduszewski, A. J, Gaensler, B. M, Smith, D. A, Sault, R. J, Fender, R. P, Spencer, R. E, de la Force, C. J, Richards, A. M. S, Garrington, S. T, Trushkin, S. A, Ghigo, F. D, Waltman, E. B, McCollough, M

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Nitric oxide synthesis is impaired in glutathione-depleted human umbilical vein endothelial cells by Ghigo, D, Alessio, P, Foco, A, Bussolino, F, Costamagna, C, Heller, R, Garbarino, G, Pescarmona, G P, Bosia, A

“…Human endothelial cells cultured from umbilical vein (HUVEC) were tested for their ability to synthesize nitric oxide (NO), which has been identified as an…”
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