Search Results - "Ghiggeri, GianMarco"

Neutrophil extracellular traps (NET) induced by different stimuli: A comparative proteomic analysis by Petretto, Andrea, Bruschi, Maurizio, Pratesi, Federico, Croia, Cristina, Candiano, Giovanni, Ghiggeri, Gianmarco, Migliorini, Paola

“…Neutrophil extracellular traps (NET) formation is part of the neutrophil response to infections, but excessive or inappropriate NETosis may trigger the…”
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The rediscovery of uromodulin (Tamm–Horsfall protein): from tubulointerstitial nephropathy to chronic kidney disease by Rampoldi, Luca, Scolari, Francesco, Amoroso, Antonio, Ghiggeri, GianMarco, Devuyst, Olivier

“…Uromodulin (Tamm–Horsfall protein) is the most abundant protein excreted in the urine under physiological conditions. It is exclusively produced in the kidney…”
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1015 Discovery and validation of anti-Formin-like 1 autoantibodies in Lupus nephritis by Prunotto, Marco, Ghiggeri, GianMarco

“…BackgroundSystemic Lupus Erythematosus (SLE) and Lupus Nephritis (LN) are prototypical autoimmune conditions. Autoantibodies (AutoAb) play a central role in…”
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Ofatumumab in two pediatric nephrotic syndrome patients allergic to rituximab by Vivarelli, Marina, Colucci, Manuela, Bonanni, Alice, Verzani, Martina, Serafinelli, Jessica, Emma, Francesco, Ghiggeri, Gianmarco

“…Background Rituximab, a chimeric anti-CD20 monoclonal antibody, is an effective treatment in steroid-dependent nephrotic syndrome (SDNS). However, some…”
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CyTOF-Enabled Analysis Identifies Class-Switched B Cells as the Main Lymphocyte Subset Associated With Disease Relapse in Children With Idiopathic Nephrotic Syndrome by Fribourg, Miguel, Cioni, Michela, Ghiggeri, GianMarco, Cantarelli, Chiara, Leventhal, Jeremy S., Budge, Kelly, Bin, Sofia, Riella, Leonardo V., Colucci, Manuela, Vivarelli, Marina, Angeletti, Andrea, Perin, Laura, Cravedi, Paolo

“…B cell depleting therapies permit immunosuppressive drug withdrawal and maintain remission in patients with frequently relapsing nephrotic syndrome (FRNS) or…”
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Case Report: Atypical Manifestations Associated With FOXP3 Mutations. The "Fil Rouge" of Treg Between IPEX Features and Other Clinical Entities? by Gentile, Micaela, Miano, Maurizio, Terranova, Paola, Giardino, Stefano, Faraci, Maura, Pierri, Filomena, Drago, Enrico, Verzola, Daniela, Ghiggeri, Gianmarco, Verrina, Enrico, Angeletti, Andrea, Cafferata, Barbara, Grossi, Alice, Ceccherini, Isabella, Caridi, Gianluca, Lugani, Francesca, Nescis, Lorenzo, Fiaccadori, Enrico, Lanino, Luca, Fenoglio, Daniela, La Porta, Edoardo

“…The Forkhead box protein P3 (FOXP3) is a transcription factor central to the function of regulatory T cells (Treg). Mutations in the gene lead to a systemic…”
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Mutation of the Mg2+ Transporter SLC41A1 Results in a Nephronophthisis-Like Phenotype by HURD, Toby W, OTTO, Edgar A, WEIBIN ZHOU, YAMANE, Tsutomo, MURAKAMI, Satoshi, CARIDI, Gianluca, GHIGGERI, Gianmarco, ABE, Takaaki, HILDEBRANDT, Friedhelm, MISHIMA, Eikan, HEON YUNG GEE, INOUE, Hana, INAZU, Masato, YAMADA, Hideomi, HALBRITTER, Jan, SEKI, George, KONISHI, Masato

“…Nephronophthisis (NPHP)-related ciliopathies are recessive, single-gene disorders that collectively make up the most common genetic cause of CKD in the first…”
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A prospective observational study of associated anomalies in Hirschsprung's disease by Pini Prato, Alessio, Rossi, Valentina, Mosconi, Manuela, Holm, Catarina, Lantieri, Francesca, Griseri, Paola, Ceccherini, Isabella, Mavilio, Domenico, Jasonni, Vincenzo, Tuo, Giulia, Derchi, Maria, Marasini, Maurizio, Magnano, Gianmichele, Granata, Claudio, Ghiggeri, Gianmarco, Priolo, Enrico, Sposetti, Lorenza, Porcu, Adelina, Buffa, Piero, Mattioli, Girolamo

“…Associated anomalies have been reported in around 20% of Hirschsprung patients but many Authors suggested a measure of underestimation. We therefore…”
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Renal fibrosis and proteomics: Current knowledge and still key open questions for proteomic investigation by Prunotto, Marco, Ghiggeri, GianMarco, Bruschi, Maurizio, Gabbiani, Giulio, Lescuyer, Pierre, Hocher, Berthold, Chaykovska, Lyubov, Berrera, Marco, Moll, Solange

“…Renal tubulo-interstitial fibrosis is a non-specific process, representing the final common pathway for all kidney diseases, irrespective of their initial…”
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Childhood Idiopathic Nephrotic Syndrome: Does the Initial Steroid Treatment Modify the Outcome? A Multicentre, Prospective Cohort Study by Pasini, Andrea, Bertulli, Cristina, Casadio, Luca, Corrado, Ciro, Edefonti, Alberto, Ghiggeri, GianMarco, Ghio, Luciana, Giordano, Mario, La Scola, Claudio, Malaventura, Cristina, Maringhini, Silvio, Mastrangelo, Antonio P., Materassi, Marco, Mencarelli, Francesca, Messina, Giovanni, Monti, Elena, Morello, William, Puccio, Giuseppe, Romagnani, Paola, Montini, Giovanni

“…Background: A great majority of children with idiopathic nephrotic syndrome will relapse after successful treatment of the initial episode. The possibility…”
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Prediction and treatment of recurrent focal segmental glomerulosclerosis after renal transplantation in children by Dall'Amico, Roberto, Ghiggeri, GianMarco, Carraro, Michele, Artero, Mary, Ghio, Luciana, Zamorani, Edgarda, Zennaro, Cristina, Basile, Giancarlo, Montini, Giovanni, Rivabella, Lucia, Cardillo, Massimo, Scalamogna, Mario, Ginevri, Fabrizio

“…The recurrence of focal segmental glomerulosclerosis (FSGS) after renal transplantation has a potentially detrimental course toward the loss of renal function…”
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The spatially resolved transcriptional profile of acute T cell-mediated rejection in a kidney allograft by Salem, Fadi, Perin, Laura, Sedrakyan, Sargis, Angeletti, Andrea, Ghiggeri, Gian Marco, Coccia, Maria Cristina, Ross, Marty, Fribourg, Miguel, Cravedi, Paolo

“…Analysis of the transcriptional profile of graft biopsies represents a promising strategy to study T cell-mediated-rejection (TCMR), also known as acute…”
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Genome-wide association analyses define pathogenic signaling pathways and prioritize drug targets for IgA nephropathy by Sanchez-Rodriguez, Elena, Zhou, Xu-Jie, Zanoni, Francesca, Zhang, Jun Y., Sanna-Cherchi, Simone, Canetta, Pietro A., Trimarchi, Hernan, Reich, Heather, Pei, York, Galesic, Kresimir, Stengel, Benedicte, Metzger, Marie, Berthoux, Francois, Berthelot, Laureline, Pillebout, Evangeline, Monteiro, Renato, Nelson, Raoul, Wyatt, Robert J., Smoyer, William, Samhar, Al-Akash, Hidalgo, Guillermo, Weng, Patricia, Sreedharan, Raji, Selewski, David, Kallash, Mahmoud, Vasylyeva, Tetyana L., Chishti, Aftab, Wenderfer, Scott E., Samsonov, Dmitry, Claes, Donna J., Akchurin, Oleh, Kovacs, Tibor, Fiaccadori, Enrico, Amoroso, Antonio, Barlassina, Cristina, Battaglia, Giovanni Giorgio, Boer, Emanuela, Bono, Luisa, Caridi, Gianluca, Coppo, Rosanna, Garozzo, Maurizio, Gesualdo, Loreto, Granata, Simona, Magistroni, Riccardo, Magnano, Andrea, Pani, Antonello, Ponticelli, Claudio, Roccatello, Dario, Salvadori, Maurizio, Salvi, Erica, Santoro, Domenico, Gembillo, Guido, Savoldi, Silvana, Izzi, Claudia, Delbarba, Elisa, Florczak, Michał, Krata, Natalia, Pączek, Leszek, Niemczyk, Stanisław, Moszczuk, Barbara, Pańczyk-Tomaszewska, Malgorzata, Perkowska-Ptasińska, Agnieszka, Bączkowska, Teresa, Durlik, Magdalena, Pawlaczyk, Krzysztof, Sikora, Przemyslaw, Kaminska, Dorota, Krajewska, Magdalena, Kuzmiuk-Glembin, Izabella, Heleniak, Zbigniew, Dębska-Slizien, Alicja, Miklaszewska, Monika, Dyga, Katarzyna, Machura, Edyta, Runowski, Dariusz, van Heel, David, Cotsapas, Chris, Franke, Andre, Annese, Vito, Gregersen, Peter K., Weirauch, Matthew, Goto, Shin, Lee, Hajeong, Park, Jin-Ho, Cho, BeLong, Choi, Murim, Van Wijk, Ans, Ars, Elisabet, Caliskan, Yasar, Kalra, Philip A., Panzer, Ulf, Rauen, Thomas, Eckardt, Kai-Uwe, Chen, Nan, Lifton, Richard P., Loos, Ruth J. F., Ionita-Laza, Iuliana, Julian, Bruce A., Novak, Jan, Scolari, Francesco

“…IgA nephropathy (IgAN) is a progressive form of kidney disease defined by glomerular deposition of IgA. Here we performed a genome-wide association study of…”
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Exosomes from human mesenchymal stem cells conduct aerobic metabolism in term and preterm newborn infants by Panfoli, Isabella, Ravera, Silvia, Podestà, Marina, Cossu, Claudia, Santucci, Laura, Bartolucci, Martina, Bruschi, Maurizio, Calzia, Daniela, Sabatini, Federica, Bruschettini, Matteo, Ramenghi, Luca Antonio, Romantsik, Olga, Marimpietri, Danilo, Pistoia, Vito, Ghiggeri, Gianmarco, Frassoni, Francesco, Candiano, Giovanni

“…Exosomes are secreted nanovesicles that are able to transfer RNA and proteins to target cells. The emerging role of mesenchymal stem cell (MSC) exosomes as…”
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Local TNF causes NFATc1-dependent cholesterol-mediated podocyte injury by Pedigo, Christopher E, Ducasa, Gloria Michelle, Leclercq, Farah, Sloan, Alexis, Mitrofanova, Alla, Hashmi, Tahreem, Molina-David, Judith, Ge, Mengyuan, Lassenius, Mariann I, Forsblom, Carol, Lehto, Markku, Groop, Per-Henrik, Kretzler, Matthias, Eddy, Sean, Martini, Sebastian, Reich, Heather, Wahl, Patricia, Ghiggeri, GianMarco, Faul, Christian, Burke, 3rd, George W, Kretz, Oliver, Huber, Tobias B, Mendez, Armando J, Merscher, Sandra, Fornoni, Alessia

“…High levels of circulating TNF and its receptors, TNFR1 and TNFR2, predict the progression of diabetic kidney disease (DKD), but their contribution to organ…”
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Neutrophil extracellular traps by Petretto, Andrea, Bruschi, Maurizio, Pratesi, Federico, Croia, Cristina, Candiano, Giovanni, Ghiggeri, Gianmarco, Migliorini, Paola

“…Neutrophil extracellular traps (NET) formation is part of the neutrophil response to infections, but excessive or inappropriate NETosis may trigger the…”
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Novel ELISA for thrombospondin type 1 domain-containing 7A autoantibodies in membranous nephropathy by Zaghrini, Christelle, Seitz-Polski, Barbara, Justino, Joana, Dolla, Guillaume, Payré, Christine, Jourde-Chiche, Noémie, Van de Logt, Anne-Els, Booth, Caroline, Rigby, Emma, Lonnbro-Widgren, Jennie, Nystrom, Jenny, Mariat, Christophe, Cui, Zhao, Wetzels, Jack F M, Ghiggeri, GianMarco, Beck, Jr, Laurence H, Ronco, Pierre, Debiec, Hanna, Lambeau, Gérard

“…Autoantibodies against phospholipase A2 receptor 1 (PLA2R1) and thrombospondin type 1 domain-containing 7A (THSD7A) are emerging as biomarkers to classify…”
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Proteome of Bovine Mitochondria and Rod Outer Segment Disks: Commonalities and Differences by Bruschi, Maurizio, Petretto, Andrea, Caicci, Federico, Bartolucci, Martina, Calzia, Daniela, Santucci, Laura, Manni, Lucia, Ramenghi, Luca A, Ghiggeri, GianMarco, Traverso, Carlo E, Candiano, Giovanni, Panfoli, Isabella

“…The retinal rod outer segment (OS) is a stack of disks surrounded by the plasma membrane, housing proteins related to phototransduction, as well as…”
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Lysyl Oxidase Activates the Transcription Activity of Human Collagene III Promoter by Giampuzzi, Monia, Botti, Gerardo, Di Duca, Marco, Arata, Lorenza, Ghiggeri, GianMarco, Gusmano, Rosanna, Ravazzolo, Roberto, Di Donato, Armando

“…Lysyl oxidase is an extracellular enzyme that controls the maturation of collagen and elastin. Lysyl oxidase and collagen III often show similar expression…”
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The human urinary exosome as a potential metabolic effector cargo by Bruschi, Maurizio, Ravera, Silvia, Santucci, Laura, Candiano, Giovanni, Bartolucci, Martina, Calzia, Daniela, Lavarello, Chiara, Inglese, Elvira, Petretto, Andrea, Ghiggeri, Gianmarco, Panfoli, Isabella

“…Exosomes are nanovesicles, derived from the endocytic pathway, released by most cell types and found in many body fluids, including urine. A variety of…”
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