Search Results - "Ghezelayagh, S"
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Minimising aseptic loosening in extreme bone resections: custom-made tumour endoprostheses with short medullary stems and extra-cortical plates
Published in The bone & joint journal (01-12-2017)“…Following the resection of an extensive amount of bone in the treatment of a tumour, the residual segment may be insufficient to accept a standard length…”
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Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women
Published in Genome medicine (15-06-2022)“…Breast cancer is a leading cause of death in premenopausal women. Progesterone drives expansion of luminal progenitor cells, leading to the development of…”
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Correction: Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women
Published in Genome medicine (19-07-2022)Get full text
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4
TP53 somatic evolution in cervical liquid-based cytology and blood from individuals with and without ovarian cancer and BRCA1 or BRCA2 germline mutations
Published in Oncogene (26-07-2024)“…Somatic TP53 mutations are prevalent in normal tissue but little is known about their association with cancer risk. Cervical liquid-based cytology (LBC),…”
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Increased TP53 somatic evolution in peritoneal washes of individuals with BRCA1 germline mutations
Published in Gynecologic oncology (01-11-2024)“…Individuals with germline BRCA1 and BRCA2 pathogenic variants (BRCA carriers) are at high risk of developing high grade serous ovarian carcinoma (HGSC). HGSC…”
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Characterizing TP53 mutations in ovarian carcinomas with and without concurrent BRCA1 or BRCA2 mutations
Published in Gynecologic oncology (01-03-2021)“…Mutations in the TP53 tumor suppressor gene are common in ovarian carcinoma (OC) but their impact on outcomes is controversial. We sought to define the…”
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Characterization of TP53 mutations in Pap test DNA of women with and without serous ovarian carcinoma
Published in Gynecologic oncology (01-02-2020)“…Pap tests hold promise as a molecular diagnostic for serous ovarian cancer, but previous studies reported limited sensitivity. Furthermore, the presence of…”
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Perceptions of risk and reward in BRCA1 and BRCA2 mutation carriers choosing salpingectomy for ovarian cancer prevention
Published in Familial cancer (01-04-2020)“…Salpingectomy with interval oophorectomy has gained traction as an ovarian cancer prevention strategy, but is not currently recommended for high risk women…”
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Uterine lavage identifies cancer mutations and increased TP53 somatic mutation burden in individuals with ovarian cancer
Published in Cancer research communications (01-10-2022)“…Current screening methods for ovarian cancer (OC) have failed to demonstrate a significant reduction in mortality. Uterine lavage combined with ultra-deep…”
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Minimising aseptic loosening in extreme boneresections: custom-made tumour endoprostheses with short medullary stems and extra-cortical plates
Published in Journal of bone and joint surgery. British volume (01-12-2017)“…AimsFollowing the resection of an extensive amount of bone in thetreatment of a tumour, the residual segment may be insufficientto accept a standard length…”
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Journal Article -
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Antiprogestins reduce epigenetic field cancerization in breast tissue of young healthy women (vol 14, 64, 2022)
Published in GENOME MEDICINE (19-07-2022)Get full text
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