Search Results - "Ghedira, Kais"
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1
Distribution of virulence and antibiotic resistance genes in Campylobacter jejuni and Campylobacter coli isolated from broiler chickens in Tunisia
Published in Journal of microbiology, immunology and infection (01-12-2022)“…Thermo-tolerant Campylobacter species are the major cause of foodborne diseases worldwide. This study aimed to evaluate the prevalence of virulence genes and…”
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2
Application and Challenge of 3rd Generation Sequencing for Clinical Bacterial Studies
Published in International journal of molecular sciences (26-01-2022)“…Over the past 25 years, the powerful combination of genome sequencing and bioinformatics analysis has played a crucial role in interpreting information encoded…”
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3
In silico comparative study of SARS-CoV-2 proteins and antigenic proteins in BCG, OPV, MMR and other vaccines: evidence of a possible putative protective effect
Published in BMC bioinformatics (26-03-2021)“…Coronavirus Disease 2019 (COVID-19) is a viral pandemic disease that may induce severe pneumonia in humans. In this paper, we investigated the putative…”
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4
The First Snake Venom KTS/Disintegrins-Integrin Interactions Using Bioinformatics Approaches
Published in Molecules (Basel, Switzerland) (31-12-2022)“…Snake venom contains a number of active molecules that have been shown to possess high anti-tumor activities; disintegrins are an excellent example among…”
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5
Structure-Function Relationship of a Novel MTX-like Peptide (MTX1) Isolated and Characterized from the Venom of the Scorpion Maurus palmatus
Published in International journal of molecular sciences (01-10-2024)“…Maurotoxin (MTX) is a 34-residue peptide from venom. It is reticulated by four disulfide bridges with a unique arrangement compared to other scorpion toxins…”
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6
Germline copy number variations in BRCA1/2 negative families: Role in the molecular etiology of hereditary breast cancer in Tunisia
Published in PloS one (27-01-2021)“…Hereditary breast cancer accounts for 5-10% of all breast cancer cases. So far, known genetic risk factors account for only 50% of the breast cancer genetic…”
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7
Identification of two novel hepatitis C virus subtype 2 from Tunisia (2v and 2w)
Published in PloS one (11-03-2021)“…Hepatitis C virus (HCV) has a high genetic diversity. Eight genotypes and 90 subtypes are currently described. Genotypes are clinically significant for…”
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8
High-quality genome sequence assembly of R.A73 Enterococcus faecium isolated from freshwater fish mucus
Published in BMC microbiology (23-10-2020)“…Whole-genome sequencing using high throughput technologies has revolutionized and speeded up the scientific investigation of bacterial genetics, biochemistry,…”
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9
Relationships between Virulence Genes and Antibiotic Resistance Phenotypes/Genotypes in Campylobacter spp. Isolated from Layer Hens and Eggs in the North of Tunisia: Statistical and Computational Insights
Published in Foods (08-11-2022)“…Globally, is a significant contributor to gastroenteritis. Efficient pathogens are qualified by their virulence power, resistance to antibiotics and epidemic…”
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10
Phylogeography and phylogeny of Rhinoviruses collected from Severe Acute Respiratory Infection (SARI) cases over successive epidemic periods in Tunisia
Published in PloS one (22-11-2021)“…Rhinoviruses (RV) are a major cause of Severe Acute Respiratory Infection (SARI) in children, with high genotypic diversity in different regions. However, RV…”
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11
A common molecular signature of patients with sickle cell disease revealed by microarray meta-analysis and a genome-wide association study
Published in PloS one (06-07-2018)“…A chronic inflammatory state to a large extent explains sickle cell disease (SCD) pathophysiology. Nonetheless, the principal dysregulated factors affecting…”
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12
Identification of a CDH12 potential candidate genetic variant for an autosomal dominant form of transgrediens and progrediens palmoplantar keratoderma in a Tunisian family
Published in Journal of human genetics (01-04-2020)“…Molecular diagnosis of rare inherited palmoplantar keratoderma (PPK) is still challenging. We investigated at the clinical and genetic level a consanguineous…”
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13
Family specific genetic predisposition to breast cancer: results from Tunisian whole exome sequenced breast cancer cases
Published in Journal of translational medicine (07-06-2018)“…A family history of breast cancer has long been thought to indicate the presence of inherited genetic events that predispose to this disease. In North Africa,…”
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14
Comparison of conventional molecular and whole-genome sequencing methods for subtyping Salmonella enterica serovar Enteritidis strains from Tunisia
Published in European journal of clinical microbiology & infectious diseases (01-03-2021)“…We sought to determine the relative value of conventional molecular methods and whole-genome sequencing (WGS) for subtyping Salmonella enterica serovar…”
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15
Draft genome sequence of Promicromonospora panici sp. nov., a novel ionizing-radiation-resistant actinobacterium isolated from roots of the desert plant Panicum turgidum
Published in Extremophiles : life under extreme conditions (2021)“…A novel strain of the genus Promicromonospora , designated PT9 T , was recovered from irradiated roots of the xerophyte Panicum turgidum collected from the…”
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16
Whole genome sequencing and phylogenetic analysis of six SARS-CoV-2 strains isolated during COVID-19 pandemic in Tunisia, North Africa
Published in BMC genomics (14-07-2021)“…Abstract Background In Tunisia a first SARS-CoV-2 confirmed case was reported in March 03, 2020. Since then, an increase of cases number was observed from…”
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17
Virulence Profiling, Multidrug Resistance and Molecular Mechanisms of Campylobacter Strains from Chicken Carcasses in Tunisia
Published in Antibiotics (Basel) (21-06-2022)“…Antibiotic resistance in foodborne pathogens is an emergent global health concern. The objectives of this study were to assess antimicrobial resistance (AMR)…”
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18
Molecular Epidemiology of SARS-CoV-2 in Tunisia (North Africa) through Several Successive Waves of COVID-19
Published in Viruses (17-03-2022)“…Documenting the circulation dynamics of SARS-CoV-2 variants in different regions of the world is crucial for monitoring virus transmission worldwide and…”
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SARS-CoV-2 Lineage A.27: New Data from African Countries and Dynamics in the Context of the COVID-19 Pandemic
Published in Viruses (09-05-2022)“…SARS-CoV-2 is constantly evolving with lineages emerging and others eclipsing. Some lineages have an important epidemiological impact and are known as variants…”
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20
Genome Tunisia Project: paving the way for precision medicine in North Africa
Published in Genome medicine (27-08-2024)“…Key discoveries and innovations in the field of human genetics have led to the foundation of molecular and personalized medicine. Here, we present the Genome…”
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