Search Results - "Ghazi, Zinah"
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Mal protein stabilizes luminal membrane PLC-β3 and negatively regulates ENaC in mouse cortical collecting duct cells
Published in American journal of physiology. Renal physiology (01-10-2019)“…Abnormally high epithelial Na channel (ENaC) activity in the aldosterone-sensitive distal nephron and collecting duct leads to hypertension. Myelin and…”
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ENaC activity is regulated by calpain-2 proteolysis of MARCKS proteins
Published in American Journal of Physiology: Cell Physiology (01-07-2017)“…We previously demonstrated a role for the myristoylated alanine-rich C kinase substrate (MARCKS) to serve as an adaptor protein in the anionic phospholipid…”
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The Pharmacological Inhibition of CaMKII Regulates Sodium Chloride Cotransporter Activity in mDCT15 Cells
Published in Biology (Basel, Switzerland) (16-12-2021)“…The thiazide-sensitive sodium chloride cotransporter (NCC) in the distal convoluted tubule is responsible for reabsorbing up to one-tenth of the total filtered…”
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4
Calpain‐2 Proteolysis of MARCKS is a Negative Feedback Regulator of ENaC
Published in The FASEB journal (01-04-2015)“…Abstract only Proteolytic and hormonal regulation of ENaC activity is important for total body sodium homeostasis and blood pressure control. We recently…”
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