Search Results - "Ghazi, C"

The colonic epithelium plays an active role in promoting colitis by shaping the tissue cytokine profile by Lyons, Jesse, Ghazi, Phaedra C, Starchenko, Alina, Tovaglieri, Alessio, Baldwin, Katherine R, Poulin, Emily J, Gierut, Jessica J, Genetti, Casie, Yajnik, Vijay, Breault, David T, Lauffenburger, Douglas A, Haigis, Kevin M

“…Inflammatory bowel disease (IBD) is a chronic condition driven by loss of homeostasis between the mucosal immune system, the commensal gut microbiota, and the…”
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New Record and Biology of the Molly Poecilia sphenops (Poeciliidae), Discovered in the Northern Sahara of Algeria by Ghazi, C., Bachir, A. Si, Idder, T.

“…This study reports data on the first observation and biology of the Molly Poecilia sphenops , an exotic fish species recently introduced into two natural and…”
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Influence of the Entrance Region on Particle Capture During Transport Through a Crack by Ghazi, C. J., Marshall, J. S.

“…A numerical study was performed of particle capture in the entrance region of a crack, with computational domain consisting of the crack channel and inlet and…”
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Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer by Ghazi, Phaedra C, O'Toole, Kayla T, Srinivas Boggaram, Sanjana, Scherzer, Michael T, Silvis, Mark R, Zhang, Yun, Bogdan, Madhumita, Smith, Bryan D, Lozano, Guillermina, Flynn, Daniel L, Snyder, Eric L, Kinsey, Conan G, McMahon, Martin

“…Mutational activation of KRAS occurs commonly in lung carcinogenesis and, with the recent U.S. Food and Drug Administration approval of covalent inhibitors of…”
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Chloroquine Sensitizes GNAQ/11 -mutated Melanoma to MEK1/2 Inhibition by Truong, Amanda, Yoo, Jae Hyuk, Scherzer, Michael T, Sanchez, John Michael S, Dale, Kali J, Kinsey, Conan G, Richards, Jackson R, Shin, Donghan, Ghazi, Phaedra C, Onken, Michael D, Blumer, Kendall J, Odelberg, Shannon J, McMahon, Martin

“…Mutational activation of or ( ), detected in >90% of uveal melanomas, leads to constitutive activation of oncogenic pathways, including MAPK and YAP. To date,…”
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Integrated in vivo multiomics analysis identifies p21-activated kinase signaling as a driver of colitis by Lyons, Jesse, Brubaker, Douglas K, Ghazi, Phaedra C, Baldwin, Katherine R, Edwards, Amanda, Boukhali, Myriam, Strasser, Samantha Dale, Suarez-Lopez, Lucia, Lin, Yi-Jang, Yajnik, Vijay, Kissil, Joseph L, Haas, Wilhelm, Lauffenburger, Douglas A, Haigis, Kevin M

“…Inflammatory bowel disease (IBD) is a chronic disorder of the gastrointestinal tract that has limited treatment options. To gain insight into the pathogenesis…”
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Substrate-based kinase activity inference identifies MK2 as driver of colitis by Strasser, Samantha Dale, Ghazi, Phaedra C, Starchenko, Alina, Boukhali, Myriam, Edwards, Amanda, Suarez-Lopez, Lucia, Lyons, Jesse, Changelian, Paul S, Monahan, Joseph B, Jacobsen, Jon, Brubaker, Douglas K, Joughin, Brian A, Yaffe, Michael B, Haas, Wilhelm, Lauffenburger, Douglas A, Haigis, Kevin M

“…Abstract Inflammatory bowel disease (IBD) is a chronic and debilitating disorder that has few treatment options due to a lack of comprehensive understanding of…”
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3:27 PM Abstract No. 16 Relationship of embolic material choice and selectivity of embolization to short-term complications after arterial embolization for pelvic trauma by Ghazi, C., Priddy, E., Dinglasan, L.

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Abstract No. 642 Does timing of radiation treatment affect endovascular stenting procedure parameters in the treatment of SVC syndrome? by Ghazi, C., Peterson, S., Coldwell, D., Dinglasan, L.

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A CO2 tracer-gas method for local air leakage detection and characterization by Ghazi, C.J., Marshall, J.S.

“…A method for local measurement of air leakage rate is presented that can be used to accurately and quickly assess leakage rates across a surface, such as…”
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Ganglioneuroma of the prostate. A novel finding in neurofibromatosis by Nassiri, M, Ghazi, C, Stivers, J R, Nadji, M

“…Urinary tract involvement in neurofibromatosis is relatively rare. We report a previously undescribed (to our knowledge) form of involvement of the prostate…”
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Elucidating the Roles of the RAS-Regulated MAPK and PI3K Pathways and Autophagy Signaling in Lung Cancer by Ghazi, Phaedra C

“…Lung cancer is the deadliest type of cancer both in the USA and worldwide. The most common type of lung cancer is lung adenocarcinoma, which originates from…”
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Inhibition of ULK1/2 and KRASG12C controls tumor growth in preclinical models of lung cancer by Ghazi, Phaedra C, O'Toole, Kayla T, Srinivas Boggaram, Sanjana, Scherzer, Michael T, Silvis, Mark R, Zhang, Yun, Bogdan, Madhumita, Smith, Bryan D, Lozano, Guillermina, Flynn, Daniel L, Snyder, Eric L, Kinsey, Conan G, McMahon, Martin

“…Mutational activation of KRAS occurs commonly in lung carcinogenesis and, with the recent U.S. Food and Drug Administration approval of covalent inhibitors of…”
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Abstract PR03: Cooperative anti-tumor effects of combined inhibition of KRASG12C plus autophagy in preclinical models of KRASG12C-driven lung cancer by Ghazi, Phaedra C., Kinsey, Conan, Bogdan, Madhumita, Smith, Bryan D., Flynn, Daniel L., McMahon, Martin

“…Approximately 25% of lung cancers are driven by mutationally-activated KRAS. A major obstacle in treating lung cancer is resistance to current therapeutic…”
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Inhibition of ULK1/2 and KRAS G12C controls tumor growth in preclinical models of lung cancer by Ghazi, Phaedra C, O'Toole, Kayla T, Srinivas Boggaram, Sanjana, Scherzer, Michael T, Silvis, Mark R, Zhang, Yun, Bogdan, Madhumita, Smith, Bryan D, Lozano, Guillermina, Flynn, Daniel L, Snyder, Eric L, Kinsey, Conan G, McMahon, Martin

“…Mutational activation of occurs commonly in lung carcinogenesis and, with the recent U.S. Food and Drug Administration approval of covalent inhibitors of KRAS…”
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The effect of chemotherapy on the gastrointestinal tract by Ghazi, C M, Chafik, N R

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Tissue-Specific Oncogenic Activity of KRAS A146T by Poulin, Emily J, Bera, Asim K, Lu, Jia, Lin, Yi-Jang, Strasser, Samantha Dale, Paulo, Joao A, Huang, Tannie Q, Morales, Carolina, Yan, Wei, Cook, Joshua, Nowak, Jonathan A, Brubaker, Douglas K, Joughin, Brian A, Johnson, Christian W, DeStefanis, Rebecca A, Ghazi, Phaedra C, Gondi, Sudershan, Wales, Thomas E, Iacob, Roxana E, Bogdanova, Lana, Gierut, Jessica J, Li, Yina, Engen, John R, Perez-Mancera, Pedro A, Braun, Benjamin S, Gygi, Steven P, Lauffenburger, Douglas A, Westover, Kenneth D, Haigis, Kevin M

“…is the most frequently mutated oncogene. The incidence of specific alleles varies between cancers from different sites, but it is unclear whether allelic…”
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Primary malignant melanomas of the lung and adrenal by Carstens, P H, Kuhns, J G, Ghazi, C

“…Malignant melanoma originating outside the skin, juxtacutaneous mucous membranes, eyes, and leptomeninges is a very rare neoplasm. Two such primary visceral…”
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Primary malignant melanoma of the common bile duct by Carstens, H B, Ghazi, C, Carnighan, R H, Brewer, M S

“…Biliary tract obstruction in a 30-year-old man was found to be caused by a malignant melanoma in the common bile duct. Melanin pigment was demonstrated by…”
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