Search Results - "Ghawas, Hussien Mansur"

Synthesis of new thiazolo-pyrrolidine–(spirooxindole) tethered to 3-acylindole as anticancer agents by Islam, Mohammad Shahidul, Ghawas, Hussien Mansur, El-Senduny, Fardous F., Al-Majid, Abdullah Mohammed, Elshaier, Yaseen A.M.M., Badria, Farid A., Barakat, Assem

“…[Display omitted] •Spirooxindole derivatives 4a–n were synthesized and tested against anti-cancer activities.•Compounds 4b–d, 4f, 4j, and 4k showed potent…”
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Substituted spirooxindole derivatives as potent anticancer agents through inhibition of phosphodiesterase 1 by Barakat, Assem, Islam, Mohammad Shahidul, Ghawas, Hussien Mansur, Al-Majid, Abdullah Mohammed, El-Senduny, Fardous F, Badria, Farid A, Elshaier, Yaseen A. M. M, Ghabbour, Hazem A

“…Spirooxindole is a promising chemo therapeutic agent. Possible targets include cancers of the liver, prostate, lung, stomach, colon, and breast. Here, we…”
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Design and synthesis of new substituted spirooxindoles as potential inhibitors of the MDM2–p53 interaction by Barakat, Assem, Islam, Mohammad Shahidul, Ghawas, Hussien Mansur, Al-Majid, Abdullah Mohammed, El-Senduny, Fardous F., Badria, Farid A., Elshaier, Yaseen A.M.M., Ghabbour, Hazem A.

“…[Display omitted] •The manuscript involved design of substituted spirooxindoles as MDM2-p53 inhibitors.•The design was corroborated via molecular docking of…”
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Synthesis of spiroindolone analogue via three components reaction of olefin with isatin and sarcosine: Anti-proliferative activity and computational studies by Al-Majid, Abdullah Mohammed, Ghawas, Hussien Mansur, Islam, Mohammad Shahidul, Soliman, Saied M., El-Senduny, Fardous F., Badria, Farid A., Ali, M., Shaik, Mohammed Rafi, Ghabbour, Hazem A., Barakat, Assem

“…Considerable attention has been focused on the [1,3] dipolar cycloaddition reaction approach of olefin with amino acid (sarcosine), and isatin which underwent…”
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