Search Results - "Ghavidel, Ata"
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A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan
Published in PLoS genetics (01-08-2015)“…Proliferating eukaryotic cells undergo a finite number of cell divisions before irreversibly exiting mitosis. Yet pathways that normally limit the number of…”
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Rapid Nuclear Exclusion of Hcm1 in Aging Saccharomyces cerevisiae Leads to Vacuolar Alkalization and Replicative Senescence
Published in G3 : genes - genomes - genetics (01-05-2018)“…The yeast, , like other higher eukaryotes, undergo a finite number of cell divisions before exiting the cell cycle due to the effects of aging. Here, we show…”
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SACCHARIS: an automated pipeline to streamline discovery of carbohydrate active enzyme activities within polyspecific families and de novo sequence datasets
Published in Biotechnology for biofuels (05-02-2018)“…Deposition of new genetic sequences in online databases is expanding at an unprecedented rate. As a result, sequence identification continues to outpace…”
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Regulation of Lysosomal Function by the DAF-16 Forkhead Transcription Factor Couples Reproduction to Aging in Caenorhabditis elegans
Published in Genetics (Austin) (01-09-2017)“…Aging in eukaryotes is accompanied by widespread deterioration of the somatic tissue. Yet, abolishing germ cells delays the age-dependent somatic decline in In…”
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Impaired tRNA Nuclear Export Links DNA Damage and Cell-Cycle Checkpoint
Published in Cell (30-11-2007)“…In response to genotoxic stress, cells evoke a plethora of physiological responses collectively aimed at enhancing viability and maintaining the integrity of…”
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A Genome Scale Screen for Mutants with Delayed Exit from Mitosis: Ire1-Independent Induction of Autophagy Integrates ER Homeostasis into Mitotic Lifespan: e1005429
Published in PLoS genetics (01-08-2015)“…Proliferating eukaryotic cells undergo a finite number of cell divisions before irreversibly exiting mitosis. Yet pathways that normally limit the number of…”
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A Skeleton of the Human Protein Interactome
Published in Cell (23-09-2005)“…In this issue of Cell, Wanker and colleagues ( Stelzl et al., 2005) present a large-scale two-hybrid map of more than 3000 putative human protein-protein…”
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