Search Results - "Ghassabeh, G H"
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Using microdialysis to analyse the passage of monovalent nanobodies through the blood–brain barrier
Published in British journal of pharmacology (01-04-2012)“…BACKGROUND AND PURPOSE Nanobodies are promising antigen‐binding moieties for molecular imaging and therapeutic purposes because of their favourable…”
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Macrophage galactose-type C-type lectins as novel markers for alternatively activated macrophages elicited by parasitic infections and allergic airway inflammation
Published in Journal of leukocyte biology (01-03-2005)“…Molecular markers, especially surface markers associated with type II, cytokine‐dependent, alternatively activated macrophages (aaMF), remain scarce. Besides…”
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Secretory Leukocyte Protease Inhibitor Promotes the Tumorigenic and Metastatic Potential of Cancer Cells
Published in Proceedings of the National Academy of Sciences - PNAS (13-05-2003)“…Because of their ability to inhibit proteases, protease inhibitors have generally been considered to counteract tumor progression and metastasis. However,…”
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Single-domain antibodies as building blocks for novel therapeutics
Published in Current opinion in pharmacology (01-10-2008)“…Antibodies are large and complex molecules, with two identical parts that bind independently of each other onto the antigen and the third part of the molecule…”
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Alternatively activated macrophages in protozoan infections
Published in Current Opinion in Immunology (01-08-2007)“…A type 1 cytokine-dependent pro-inflammatory response inducing classically activated macrophages is crucial for parasite control during protozoan infections…”
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Arginase-1 and Ym1 are markers for murine, but not human, alternatively activated myeloid cells
Published in The Journal of immunology (1950) (01-06-2005)Get full text
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Alternatively activated macrophages during parasite infections
Published in Trends in parasitology (01-03-2004)“…Depending on the cytokine environment, macrophages can differentiate into distinct subsets that perform specific immunological roles. In this regard, the…”
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Reactive Oxygen Species and 12/15-Lipoxygenase Contribute to the Antiproliferative Capacity of Alternatively Activated Myeloid Cells Elicited during Helminth Infection
Published in The Journal of immunology (1950) (15-05-2005)“…Understanding the role of CD11b(+)GR-1(+) myeloid suppressor cells in the immune suppression and immunoregulation associated with a variety of diseases may…”
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Secretory Leukocyte Protease Inhibitor in Cancer Development
Published in Annals of the New York Academy of Sciences (01-12-2004)“…: Secretory leukocyte protease inhibitor (SLPI), an epithelial‐specific serine protease inhibitor of the whey acidic protein (WAP) family, exerts broad…”
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Antibody technology in proteomics
Published in Briefings in functional genomics & proteomics (01-07-2008)“…Today's proteomic analyses are generating increasing numbers of biomarkers, making it essential to possess highly specific probes able to recognize those…”
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