Search Results - "Ghashghaee, Nazanin Bohlooli"
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Role of the C-terminus mobile domain of cardiac troponin I in the regulation of thin filament activation in skinned papillary muscle strips
Published in Archives of biochemistry and biophysics (15-06-2018)“…The C-terminus mobile domain of cTnI (cTnI-MD) is a highly conserved region which stabilizes the actin-cTnI interaction during the diastole. Upon Ca2+-binding…”
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Journal Article -
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Functional significance of C-terminal mobile domain of cardiac troponin I
Published in Archives of biochemistry and biophysics (15-11-2017)“…Ca2+-regulation of cardiac contractility is mediated through the troponin complex, which comprises three subunits: cTnC, cTnI, and cTnT. As intracellular…”
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Direct Troponin-Myosin Interaction Enhances ATPase Activity of Cardiac HMM
Published in Biophysical journal (27-01-2015)Get full text
Journal Article -
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Sarcomere length dependent effects on the interaction between cTnC and cTnI in skinned papillary muscle strips
Published in Archives of biochemistry and biophysics (01-07-2016)“…Sarcomere length dependent activation (LDA) of myocardial force development is the cellular basis underlying the Frank-Starling law of the heart, but it is…”
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Functional Significance of C-Terminal Mobile Domain of Cardiac Troponin I
Published in Biophysical journal (03-02-2017)Get full text
Journal Article -
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Functional Significance of the Mobile Domain of Cardiac Troponin I
Published 2018“…Protein-protein interactions between the thick and thin filaments and among thin filament proteins, particularly the troponin complex, play a vital role in…”
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Dissertation -
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Direct interaction between troponin and myosin enhances the ATPase activity of heavy meromyosin
Published in Biológia (01-06-2017)“…Contractility of the heart muscle is a result of sliding movements between thick and thin filaments, produced by interactions between actin and myosin during…”
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Journal Article