Nephrotic syndrome and Guillan-Barre syndrome : a rare association in child

Only few cases of nephrotic syndrome associated with Guillain-Barre Syndrome (GBS) have been reported in the adult and pediatric literature. A 3-year-old boy was initially admitted to our hospital following five days of progressive weakness of his extremities, fatigue, right leg pain and numbness. T...

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Bibliographic Details
Published in:	Saudi journal of kidney diseases and transplantation Vol. 21; no. 1; pp. 135 - 137
Main Authors:	Qarqash, Tahar, Mrad, Sonia Mazigh, Harz Allah, Qays, Bu Yahya, Ulfah, Azzah, Sumud al-Gharbi, Gharsallah, Lamya, Khalifi, Ibtisam, Bu Kathir, Samir
Format:	Journal Article
Language:	English
Published:	Riyadh, Saudi Arabia Saudi Center for Organ Transplantation 2010 Medknow Publications and Media Pvt. Ltd Wolters Kluwer Medknow Publications
Subjects:	Adolescent Adult Biopsy Care and treatment Case studies Child, Preschool Diagnosis Fatigue - etiology Female Guillain-Barre syndrome Guillain-Barre Syndrome - complications Guillain-Barre Syndrome - diagnosis Guillain-Barre Syndrome - drug therapy Guillain-Barré syndrome in children Health aspects Humans Hypesthesia - etiology Immunoglobulins, Intravenous - therapeutic use Immunosuppressive agents Leg Male Middle Aged Muscle Weakness - etiology Nephrotic syndrome Nephrotic Syndrome - diagnosis Nephrotic Syndrome - drug therapy Nephrotic Syndrome - etiology Nephrotic syndrome in children Neurologic Examination Pain - etiology Patient outcomes Risk factors Steroids - therapeutic use Treatment Outcome الأطفال التشخيص المتلازمة الكلوية المضاعفات متلازمة غيلان باريه Saudi Arabia
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Summary:	Only few cases of nephrotic syndrome associated with Guillain-Barre Syndrome (GBS) have been reported in the adult and pediatric literature. A 3-year-old boy was initially admitted to our hospital following five days of progressive weakness of his extremities, fatigue, right leg pain and numbness. There was no past history of renal or neurological disease. Cerebrospinal fluid studies showed a protein level of 92 mg/dL and a white cell count of 1 per high-power field. The diagnosis of GBS was verified with a nerve conduction velocity test as well as. The GBS symptoms improved gradually on intravenous immunoglobulin. Three weeks later, he developed severe proteinuria and edema; laboratory investigation showed nephrotic syndrome which responded to steroid therapy. Renal biopsy showed minimal change glomerulonephritis. He remained free of proteinuria during his 20 months of follow-up.
Bibliography:	ObjectType-Case Study-2 SourceType-Scholarly Journals-1 ObjectType-Feature-4 content type line 23 ObjectType-Report-1 ObjectType-Article-3
ISSN:	1319-2442 2320-3838