Search Results - "Gharibeh, Lara"

GATA6 Regulates Aortic Valve Remodeling, and Its Haploinsufficiency Leads to Right-Left Type Bicuspid Aortic Valve by Gharibeh, Lara, Komati, Hiba, Bossé, Yohan, Boodhwani, Munir, Heydarpour, Mahyar, Fortier, Megan, Hassanzadeh, Romina, Ngu, Janet, Mathieu, Patrick, Body, Simon, Nemer, Mona

“…Bicuspid aortic valve (BAV), the most common congenital heart defect affecting 1% to 2% of the population, is a major risk factor for premature aortic valve…”
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Clr-f expression regulates kidney immune and metabolic homeostasis by Zein, Haggag S., Abou-Samra, Elias, Scur, Michal, Gutsol, Alex, Hall, Clayton W., Dasgupta, Bishal, Gharibeh, Lara, Abujamel, Turki, Medina-Luna, Daniel, Gamage, Gayani S., Pelino, Tessa J., Nemer, Mona, Rahim, Mir Munir A., Steinle, Alexander, Parsons, Brendon D., Makrigiannis, Andrew P.

“…The C-type lectin-related protein, Clr-f, encoded by Clec2h in the mouse NK gene complex (NKC), is a member of a family of immune regulatory lectins that guide…”
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Surgical Techniques for the Treatment of Anomalous Origin of Right Coronary Artery From the Left Sinus: A Comparative Review by Gharibeh, Lara, Rahmouni, Kenza, Hong, Seok Joon, Crean, Andrew M, Grau, Juan B

“…The anomalous aortic origin of the right coronary artery (AAORCA) from the left sinus is a congenital anomaly affecting both the origin and course of the right…”
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Cardiac Neural Crest Cells: Their Rhombomeric Specification, Migration, and Association with Heart and Great Vessel Anomalies by Schussler, Olivier, Gharibeh, Lara, Mootoosamy, Parmeseeven, Murith, Nicolas, Tien, Vannary, Rougemont, Anne-Laure, Sologashvili, Tornike, Suuronen, Erik, Lecarpentier, Yves, Ruel, Marc

“…Outflow tract abnormalities are the most frequent congenital heart defects. These are due to the absence or dysfunction of the two main cell types, i.e.,…”
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Implications of Bicuspid Aortic Valve Disease and Aortic Stenosis/Insufficiency as Risk Factors for Thoracic Aortic Aneurysm by Jabagi, Habib, Levine, Dov, Gharibeh, Lara, Camillo, Chiara, Castillero, Estibaliz, Ferrari, Giovanni, Takayama, Hiroo, Grau, Juan B

“…Bicuspid Aortic Valves (BAV) are associated with an increased incidence of thoracic aortic aneurysms (TAA). TAA are a common aortic pathology characterized by…”
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Patient Characteristics and Outcomes Associated with Sentinel Protection Device Use in Patients with Aortic Valve Disease Undergoing TAVR in a "Real-World" Setting by Jabagi, Habib, Shaw, Richard E, Gharibeh, Lara, Tayal, Rajiv, Rahim, Hussein, Kim, Francis, Zapolanski, Alex, Grau, Juan B

“…Transcatheter aortic valve replacement (TAVR) has become the dominant treatment for aortic valve disease. While TAVR safety has improved over time, concern…”
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Glutaredoxin-2 controls cardiac mitochondrial dynamics and energetics in mice, and protects against human cardiac pathologies by Kanaan, Georges N., Ichim, Bianca, Gharibeh, Lara, Maharsy, Wael, Patten, David A., Xuan, Jian Ying, Reunov, Arkadiy, Marshall, Philip, Veinot, John, Menzies, Keir, Nemer, Mona, Harper, Mary-Ellen

“…Glutaredoxin 2 (GRX2), a mitochondrial glutathione-dependent oxidoreductase, is central to glutathione homeostasis and mitochondrial redox, which is crucial in…”
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Comparative Analysis Following Implementation of Two Types of Y-Composite Multiarterial Revascularization Strategies at a Single Academic Institution by Gharibeh, Lara, Hosoyama, Katsuhiro, Glineur, David, Shaw, Richard E, Lapierre, Harry, Ruel, Marc, Grau, Juan B

“…Background We compared early outcomes, at a single academic institution, of implementing full coronary revascularization in coronary artery bypass grafting…”
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GATA4 Loss-of-Function Mutations Underlie Familial Tetralogy of Fallot by Yang, Yi-Qing, Gharibeh, Lara, Li, Ruo-Gu, Xin, Yuan-Feng, Wang, Juan, Liu, Zhong-Min, Qiu, Xing-Biao, Xu, Ying-Jia, Xu, Lei, Qu, Xin-Kai, Liu, Xu, Fang, Wei-Yi, Huang, Ri-Tai, Xue, Song, Nemer, Georges

“…ABSTRACT Tetralogy of Fallot (TOF) represents the most common form of cyanotic congenital heart disease and accounts for significant morbidity and mortality in…”
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Extended Myectomy for Hypertrophic Cardiomyopathy: Early Outcomes From a Nascent Centre of Excellence in Canada by Crean, Andrew M., Gharibeh, Lara, Saleem, Zain, Glineur, David, Maharaj, Gyaandeo, Grau, Juan B.

“…Hypertrophic cardiomyopathy (HCM) is one of the commonest inherited cardiac abnormalities. The disorder is clinically and genetically heterogeneous and is…”
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Inhibition of Cardiomyogenesis in Embryocarcinoma Cells Induced by Long-Term High Level of Glucose by Li, Wen-Juan, Guo, Qian-Qian, Gharibeh, Lara, Xu, Rang, Chen, Sun, Sun, Kun

“…Abstract Background/Aims: Cardiac myocytes constitute the first differentiated cell type during mammalian heart formation with the ability to beat…”
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From embryogenesis to adulthood: Critical role for GATA factors in heart development and function by Whitcomb, Jamieson, Gharibeh, Lara, Nemer, Mona

“…Cardiac development is governed by a complex network of transcription factors (TFs) that regulate cell fates in a spatiotemporal manner. Among these, the GATA…”
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GATA6 is a regulator of sinus node development and heart rhythm by Gharibeh, Lara, Yamak, Abir, Whitcomb, Jamieson, Lu, Aizhu, Joyal, Mathieu, Komati, Hiba, Liang, Wenbin, Fiset, Céline, Nemer, Mona

“…The sinus node (SAN) is the primary pacemaker of the human heart, and abnormalities in its structure or function cause sick sinus syndrome, the most common…”
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Systematic Approach to the Calcified Mitral Valve Apparatus at Time of Mitral Valve Replacement by Rahmouni, Kenza, Deng, Mimi, Gharibeh, Lara, Elmistekawy, Elsayed, Grau, Juan, Mesana, Thierry, Chan, Vincent

“…Mitral annular calcification (MAC) represents a surgical challenge to mitral valve replacement. The presence of MAC at the time of mitral valve replacement is…”
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Guiding Cardiac Conduction With GATA by Nemer, Mona, Gharibeh, Lara

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Autophagy Is Differentially Regulated in Leukocyte and Nonleukocyte Foam Cells During Atherosclerosis by Robichaud, Sabrina, Rasheed, Adil, Pietrangelo, Antonietta, Doyoung Kim, Anne, Boucher, Dominique M., Emerton, Christina, Vijithakumar, Viyashini, Gharibeh, Lara, Fairman, Garrett, Mak, Esther, Nguyen, My-Anh, Geoffrion, Michele, Wirka, Robert, Rayner, Katey J., Ouimet, Mireille

“…Atherosclerosis is characterized by an accumulation of foam cells within the arterial wall, resulting from excess cholesterol uptake and buildup of cytosolic…”
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Severe Mitral Annular Calcification in Two Cases of Hypertrophic Obstructive Cardiomyopathy by Gharibeh, Lara, Rahmouni, Kenza, Crean, Andrew M., Castillo, Javier, Grau, Juan B.

“…Management of patients with hypertrophic obstructive cardiomyopathy and severe mitral annular calcification can be challenging. Our cases highlight the…”
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Abstract 102: Autophagy Is Differentially Regulated In Leukocyte And Nonleukocyte Foam Cells During Atherosclerosis by Robichaud, Sabrina, Rasheed, Adil, Pietrangelo, Antonietta, Kim, Anne, Boucher, Dominique, Emerton, Chrissy, Vijithakumar, Viyashini, Gharibeh, Lara, Fairman, Garrett, Mak, Esther, Nguyen, My-anh, Geoffrion, Michele, Wirka, Robert, Rayner, Katey J, Ouimet, Mireille I

“…Atherosclerosis is characterized by a build-up of foam cells in the arterial wall, resulting from excess cholesterol uptake and accumulation of cytosolic lipid…”
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Abstract 207: Autophagy Is Differentially Regulated In Leukocyte And Nonleukocyte Foam Cells During Atherosclerosis by Robichaud, Sabrina, Rasheed, Adil, Pietrangelo, Antonietta, Kim, Anne, Boucher, Dominique, Emerton, Chrissy, Vijithakumar, Viyashini, Gharibeh, Lara, Fairman, Garrett, Mak, Esther, Nguyen, My-anh, Geoffrion, Michele, Wirka, Robert, Rayner, Katey J, Ouimet, Mireille I

“…Atherosclerosis is characterized by a build-up of foam cells in the arterial wall, resulting from excess cholesterol uptake and accumulation of cytosolic lipid…”
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Conduits' Biology Regulates the Outcomes of Coronary Artery Bypass Grafting by Gharibeh, Lara, Ferrari, Giovanni, Ouimet, Mireille, Grau, Juan B

“…Coronary artery bypass graft (CABG) is the gold standard for coronary surgical revascularization. Retrospective, prospective, and meta-analysis studies looking…”
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