Search Results - "Gharib, Mennat"

An updated protocol for the cost-effective and weekend-free culture of human induced pluripotent stem cells by Lyra-Leite, Davi Marco, Fonoudi, Hananeh, Gharib, Mennat, Burridge, Paul W.

“…The protocol provided here describes methodologies for making a highly cost-effective, chemically defined medium for culturing hiPSCs we call B8 medium. The…”
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Identification of Drug Transporter Genomic Variants and Inhibitors That Protect Against Doxorubicin-Induced Cardiotoxicity by Magdy, Tarek, Jouni, Mariam, Kuo, Hui-Hsuan, Weddle, Carly J., Lyra-Leite, Davi, Fonoudi, Hananeh, Romero-Tejeda, Marisol, Gharib, Mennat, Javed, Hoor, Fajardo, Giovanni, Ross, Colin J.D., Carleton, Bruce C., Bernstein, Daniel, Burridge, Paul W.

“…Multiple pharmacogenomic studies have identified the synonymous genomic variant rs7853758 (G > A, L461L) and the intronic variant rs885004 in (solute carrier…”
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RARG variant predictive of doxorubicin-induced cardiotoxicity identifies a cardioprotective therapy by Magdy, Tarek, Jiang, Zhengxin, Jouni, Mariam, Fonoudi, Hananeh, Lyra-Leite, Davi, Jung, Gwanghyun, Romero-Tejeda, Marisol, Kuo, Hui-Hsuan, Fetterman, K. Ashley, Gharib, Mennat, Burmeister, Brian T., Zhao, Mingming, Sapkota, Yadav, Ross, Colin J., Carleton, Bruce C., Bernstein, Daniel, Burridge, Paul W.

“…Doxorubicin is an anthracycline chemotherapy agent effective in treating a wide range of malignancies, but its use is limited by dose-dependent cardiotoxicity…”
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'Channeling' therapeutic discovery for epileptic encephalopathy through iPSC technologies by Simkin, Dina, Ambrosi, Christina, Marshall, Kelly A, Williams, Luis A, Eisenberg, Jordyn, Gharib, Mennat, Dempsey, Graham T, George, Jr, Alfred L, McManus, Owen B, Kiskinis, Evangelos

“…Induced pluripotent stem cell (iPSC) and gene editing technologies have revolutionized the field of in vitro disease modeling, granting us access to…”
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Identification of Drug Transporter Genomic Variants and Inhibitors that Protect Against Doxorubicin–Induced Cardiotoxicity by Magdy, Tarek, Jouni, Mariam, Kuo, Hui–Hsuan, Weddle, Carly J., Lyra–Leite, Davi, Fonoudi, Hananeh, Romero–Tejeda, Marisol, Gharib, Mennat, Javed, Hoor, Fajardo, Giovanni, Ross, Colin J. D., Carleton, Bruce C., Bernstein, Daniel, Burridge, Paul W.

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Nutritional requirements of human induced pluripotent stem cells by Lyra-Leite, Davi M., Copley, Raymond R., Freeman, Phillip P., Pongpamorn, Praeploy, Shah, Disheet, McKenna, Donald E., Lenny, Brian, Pinheiro, Emily A., Weddle, Carly J., Gharib, Mennat, Javed, Hoor, Fonoudi, Hananeh, Sapkota, Yadav, Burridge, Paul W.

“…The nutritional requirements for human induced pluripotent stem cell (hiPSC) growth have not been extensively studied. Here, building on our prior work that…”
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Functional Validation of Doxorubicin-Induced Cardiotoxicity-Related Genes by Fonoudi, Hananeh, Jouni, Mariam, Cejas, Romina B., Magdy, Tarek, Blancard, Malorie, Ge, Ning, Shah, Disheet A., Lyra-Leite, Davi M., Neupane, Achal, Gharib, Mennat, Jiang, Zhengxin, Sapkota, Yadav, Burridge, Paul W.

“…Genome-wide association studies and candidate gene association studies have identified more than 180 genetic variants statistically associated with…”
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