Search Results - "Gharib, Bouchra"

Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer's disease: Alleviation by pantethine by van Gijsel-Bonnello, Manuel, Baranger, Kévin, Benech, Philippe, Rivera, Santiago, Khrestchatisky, Michel, de Reggi, Max, Gharib, Bouchra

“…Astrocytes play critical roles in central nervous system homeostasis and support of neuronal function. A better knowledge of their response may both help…”
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Long-Term Pantethine Treatment Counteracts Pathologic Gene Dysregulation and Decreases Alzheimer’s Disease Pathogenesis in a Transgenic Mouse Model by Baranger, Kevin, van Gijsel-Bonnello, Manuel, Stephan, Delphine, Carpentier, Wassila, Rivera, Santiago, Khrestchatisky, Michel, Gharib, Bouchra, De Reggi, Max, Benech, Philippe

“…The low-molecular weight thiol pantethine, known as a hypolipidemic and hypocholesterolemic agent, is the major precursor of co-enzyme A. We have previously…”
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Correction: Metabolic changes and inflammation in cultured astrocytes from the 5xFAD mouse model of Alzheimer's disease: Alleviation by pantethine by van Gijsel-Bonnello, Manuel, Baranger, Kévin, Benech, Philippe, Rivera, Santiago, Khrestchatisky, Michel, de Reggi, Max, Gharib, Bouchra

“…[This corrects the article DOI: 10.1371/journal.pone.0175369.]…”
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Protection against cerebral malaria by the low-molecular-weight thiol pantethine by Penet, Marie-France, Abou-Hamdan, Mhamad, Coltel, Nicolas, Cornille, Emilie, Grau, Georges E, de Reggi, Max, Gharib, Bouchra

“…We report that administration of the low-molecular-weight thiol pantethine prevented the cerebral syndrome in Plasmodium berghei ANKA-infected mice. The…”
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Effect of Pantethine on Ovarian Tumor Progression and Choline Metabolism by Penet, Marie-France, Krishnamachary, Balaji, Wildes, Flonne, Mironchik, Yelena, Mezzanzanica, Delia, Podo, Franca, de Reggi, Max, Gharib, Bouchra, Bhujwalla, Zaver M

“…Epithelial ovarian cancer remains the leading cause of death from gynecologic malignancy among women in developed countries. New therapeutic strategies…”
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Enhancement of L-3-hydroxybutyryl-CoA dehydrogenase activity and circulating ketone body levels by pantethine. Relevance to dopaminergic injury by Cornille, Emilie, Abou-Hamdan, Mhamad, Khrestchatisky, Michel, Nieoullon, André, de Reggi, Max, Gharib, Bouchra

“…The administration of the ketone bodies hydroxybutyrate and acetoacetate is known to exert a protective effect against metabolic disorders associated with…”
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Lithostathine, the Presumed Pancreatic Stone Inhibitor, Does Not Interact Specifically with Calcium Carbonate Crystals by De Reggi, M, Gharib, B, Patard, L, Stoven, V

“…Lithostathine (pancreatic stone protein, Reg protein) is, in addition to albumin, the major nonenzymatic protein of the pancreatic juice. It has been assumed…”
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Infection and disease in human schistosomiasis mansoni are under distinct major gene control by Dessein, Alain J, Marquet, Sandrine, Henri, Sandrine, El Wali, Nasr Eldin M.A, Hillaire, Dominique, Rodrigues, Virmondes, Prata, Aluizio, Ali, Qurashi Mohamed, Gharib, Bouchra, de Reggi, Max, Magzoub, Mubarak M.A, Saeed, Osman K, Abdelhameed, Ahmed A, Abel, Laurent

“…Considerable evidence has accumulated in the past few years indicating that infection levels and prevalence of schistosome infections in endemic populations…”
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Pantethine Alters Lipid Composition and Cholesterol Content of Membrane Rafts, With Down-Regulation of CXCL12-Induced T Cell Migration by van Gijsel-Bonnello, Manuel, Acar, Niyazi, Molino, Yves, Bretillon, Lionel, Khrestchatisky, Michel, de Reggi, Max, Gharib, Bouchra

“…Pantethine, a natural low‐molecular‐weight thiol, shows a broad activity in a large range of essential cellular pathways. It has been long known as a…”
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Molecular hydrogen attenuates radiation-induced nucleobase damage to DNA in aerated aqueous solutions by Abou-Hamdan, Mhamad, Gardette, Bernard, Cadet, Jean, Gharib, Bouchra, De Reggi, Max, Douki, Thierry, Triantaphylides, Christian

“…Purpose: The main aim of the present study is to gain mechanistic insights into the modulating effect of molecular hydrogen on the γ-radiation-induced…”
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Abstract 324: Pantethine, a new therapeutic approach against ovarian cancer by Penet, Marie-France, Canevari, Silvana, Podo, Franca, de Reggi, Max, Gharib, Bouchra, Bhujwalla, Zaver M.

“…Abstract Ovarian cancer is the leading cause of death from gynecologic malignancy among women in developed countries with an estimated incidence of 205,000…”
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Imaging Experimental Cerebral Malaria In Vivo: Significant Role of Ischemic Brain Edema by Penet, Marie-France, Viola, Angele, Confort-Gouny, Sylviane, Le Fur, Yann, Duhamel, Guillaume, Kober, Frank, Ibarrola, Danielle, Izquierdo, Marguerite, Coltel, Nicolas, Gharib, Bouchra, Grau, Georges E, Cozzone, Patrick J

“…The first in vivo magnetic resonance study of experimental cerebral malaria is presented. Cerebral involvement is a lethal complication of malaria. To explore…”
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Pantethine Down-Regulates Leukocyte Recruitment and Inflammatory Parameters in a Mouse Model of Allergic Airway Inflammation by Abou-Hamdan, Mhamad, Gharib, Bouchra, Bajenoff, Marc, Julia, Valérie, de Reggi, Max

“…BACKGROUND Migration of leukocytes into airways is the hallmark of allergic asthma. The aim of this study was to target the pathological process using…”
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A gene homologous to the reg gene is expressed in the human pancreas by Bartoli, Catherine, Gharib, Bouchra, Giorgi, Dominique, Sansonetti, Alice, Dagorn, Jean-Charles, Bergé-Lefranc, Jean-Louis

“…We have determined the nucleotide sequence of reg1 a human genomic DNA fragment homologous to the reg gene which is expressed in the exocrine pancreas and…”
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Vanin-1(-/-) mice show decreased NSAID- and Schistosoma-induced intestinal inflammation associated with higher glutathione stores by Martin, Florent, Penet, Marie-France, Malergue, Fabrice, Lepidi, Hubert, Dessein, Alain, Galland, Franck, de Reggi, Max, Naquet, Philippe, Gharib, Bouchra

“…Vanin-1 is a membrane-anchored pantetheinase highly expressed in the gut and liver. It hydrolyzes pantetheine to pantothenic acid (vitamin B5) and the…”
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The glycan moiety of human pancreatic lithostathine. Structure characterization and possible pathophysiological implications by De Reggi, M, Capon, C, Gharib, B, Wieruszeski, J M, Michel, R, Fournet, B

“…Lithostathine, also known as pancreatic stone protein, pancreatic thread protein or regenerating protein, is a glycoprotein which is normally found in the…”
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Ecdysteroids in urine of African patients infected with helminths by Baswaïd, S, Gharib, B, Doumbo, O, Quilici, M, de Reggi, M

“…The insect molting hormone and related compounds (ecdysteroids) have been found in patients infected with helminths. To investigate this phenomenon, we…”
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Development of eosinophil peroxidase activity and concomitant alteration of the antioxidant defenses in the liver of mice infected with Schistosoma mansoni by Gharib, Bouchra, Abdallahi, Ould Mohamed Salem, Dessein, Hélia, Reggi, Max De

“…Background/Aims: The tropical parasite Schistosoma mansoni causes granulomatous inflammation following lodging of eggs in portal capillaries. In vitro studies…”
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Circulating markers of oxidative stress and liver fibrosis in Sudanese subjects at risk of schistosomiasis and hepatitis by Eboumbou, Carole, Steghens, Jean-Paul, Abdallahi, Ould Mohamed Salem, Mirghani, Adil, Gallian, Pierre, van Kappel, Anne, Qurashi, A., Gharib, Bouchra, De Reggi, Max

“…Epidemiological studies in the developing world are frequently biased by the simultaneous presence of several infectious pathogens. In the present study, we…”
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Imaging experimental cerebral malaria in vivo: significant role of ischemic brain edema by Penet, Marie-France, Viola, Angèle, Confort-Gouny, Sylviane, Le Fur, Yann, Duhamel, Guillaume, Kober, F., Ibarrola, Danielle, Izquierdo, Marguerite, Coltel, Nicolas, Gharib, Bouchra, Grau, Georges E, Cozzone, Patrick J

“…The first in vivo magnetic resonance study of experimental cerebral malaria is presented. Cerebral involvement is a lethal complication of malaria. To explore…”
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