Search Results - "Ghareeb, Doaa A."
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Neuroprotective effect of berberine against environmental heavy metals-induced neurotoxicity and Alzheimer's-like disease in rats
Published in Food and chemical toxicology (01-01-2018)“…Heavy metals are reported as neurodegenerative disorders progenitor. They play a role in the precipitation of abnormal β-amyloid protein and…”
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Forecasting of potential anti-inflammatory targets of some immunomodulatory plants and their constituents using in vitro, molecular docking and network pharmacology-based analysis
Published in Scientific reports (12-06-2023)“…Most synthetic immunomodulatory medications are extremely expensive, have many disadvantages and suffer from a lot of side effects. So that, introducing…”
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Tackling neuroinflammation and cholinergic deficit in Alzheimer's disease: Multi-target inhibitors of cholinesterases, cyclooxygenase-2 and 15-lipoxygenase
Published in European journal of medicinal chemistry (01-04-2019)“…Neuroinflammation and cholinergic deficit are key detrimental processes involved in Alzheimer's disease. Hence, in the search for novel and effective treatment…”
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Neuroprotective effect of ipriflavone against scopolamine-induced memory impairment in rats
Published in Psychopharmacology (01-10-2017)“…Background Alzheimer’s disease is an age-related neurodegenerative disorder characterized clinically by a progressive loss of memory and cognitive functions…”
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Preparation, physicochemical characterization, and bioactivity evaluation of berberine-entrapped albumin nanoparticles
Published in Scientific reports (19-10-2022)“…Berberine (BBR) is an isoquinoline alkaloid with several clinical therapeutic applications. Its low water solubility, absorption, and cellular bioavailability…”
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Selenium nanoparticles coated bacterial polysaccharide with potent antimicrobial and anti-lung cancer activities
Published in Scientific reports (10-12-2023)“…Bacterial exopolysaccharides are homopolymeric or heteropolymeric polysaccharides with large molecular weights (10–1000 kDa). Exopolysaccharides' functional…”
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Aerobic phenol degradation using native bacterial consortium via ortho-and meta-cleavage pathways
Published in Frontiers in microbiology (05-08-2024)“…Effective bioremediation of a phenol-polluted environment harnesses microorganisms' ability to utilize hazardous compounds as beneficial degraders. In the…”
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Metabolic profiling of Lantana camara L. using UPLC-MS/MS and revealing its inflammation-related targets using network pharmacology-based and molecular docking analyses
Published in Scientific reports (01-09-2022)“…Lantana camara L. is widely used in folk medicine for alleviation of inflammatory disorders, but studies that proved this folk use and that revealed the…”
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Novel Amoxicillin-Loaded Sericin Biopolymeric Nanoparticles: Synthesis, Optimization, Antibacterial and Wound Healing Activities
Published in International journal of molecular sciences (01-10-2022)“…Infected wounds are a major threat among diabetic patients. Technological advancements are currently increasing the number of new adjunctive therapies that may…”
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Correction: Diad et al. Novel Amoxicillin-Loaded Sericin Biopolymeric Nanoparticles: Synthesis, Optimization, Antibacterial and Wound Healing Activities. Int. J. Mol. Sci. 2022, 23 , 11654
Published in International journal of molecular sciences (25-06-2024)“…In the original publication [...]…”
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Potential anti-proliferative activity of Salix mucronata and Triticum spelta plant extracts on liver and colorectal cancer cell lines
Published in Scientific reports (07-03-2023)“…Cancer’s etiology is linked to oxidative stress. As a result, it's vital to find effective natural antioxidant remedies. Salix mucronata and Triticum spelta…”
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HR LC-MS/MS metabolomic profiling of Yucca aloifolia fruit and the potential neuroprotective effect on rotenone-induced Parkinson's disease in rats
Published in PloS one (28-02-2023)“…Yucca aloifolia L. fruit (Yucca or Spanish bayonet, family Asparagaceae) is recognized for its purplish red color reflecting its anthocyanin content, which has…”
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Ipriflavone and Ipriflavone loaded albumin nanoparticles reverse lipopolysaccharide induced neuroinflammation in rats
Published in PloS one (21-08-2020)“…Background Neuroinflammation causes neurodegenerative conditions like Alzheimer's disease (AD). Ipriflavone (IP), therapeutic compound to postmenopausal…”
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In vitro and in vivo anti-colorectal cancer effect of the newly synthesized sericin/propolis/fluorouracil nanoplatform through modulation of PI3K/AKT/mTOR pathway
Published in Scientific reports (29-01-2024)“…The present work aimed to assess the potential effect of sericin/propolis/fluorouracil nanoformula against colorectal cancer (CRC) (the fourth most common…”
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Trichoderma reesei fungal degradation boosted the potentiality of date pit extract in fighting scopolamine-induced neurotoxicity in male rats
Published in Scientific reports (21-07-2021)“…Date pits are nutritious by-products, containing high levels of indigestible carbohydrates and polyphenols. To maximize the biological effects of the active…”
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In vitro biological activities and in vivo hepatoprotective role of brown algae-isolated fucoidans
Published in Environmental science and pollution research international (01-04-2021)“…Brown seaweeds are rich in polysaccharides, such as fucoidan (FUC) which has shown beneficial effects in several medical conditions. The aim of the present…”
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Synthesized Nanorods Hydroxyapatite by Microwave-Assisted Technology for In Vitro Osteoporotic Bone Regeneration through Wnt/β-Catenin Pathway
Published in Materials (05-10-2021)“…This research presents an optimal and inexpensive, without any additives, method for the synthesis and sintering of hydroxyapatite (HA) by microwave-assisted…”
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Characterization, in-silico, and in-vitro study of a new steroid derivative from Ophiocoma dentata as a potential treatment for COVID-19
Published in Scientific reports (07-04-2022)“…The medicinal potential of marine invertebrates' bioactive components that may act as anti-COVID-19 demonstrated promising results. Ophiocoma dentata , which…”
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Baculovirus displaying SARS-CoV-2 spike RBD promotes neutralizing antibody production in a mouse model
Published in Journal of Genetic Engineering and Biotechnology (01-12-2023)“…Background There is always a need for a safe and efficient vaccine platform, especially when facing a pandemic such as COVID-19. Most of the SARS-CoV-2-based…”
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