Nicolau Syndrome due to Penicillin Injection: A Report of 3 Cases without Long-Term Complication

Nicolau Syndrome due to Penicillin Injection: A Report of 3 Cases without Long-Term Complication

Nicolau syndrome (NS) or livedo-like dermatitis is a rare complication of injection of various medications such as penicillin. The pathophysiology of this events is not clear, but some hypotheses are suggested, such as sympathetic nerve stimulation, embolic occlusion, inflammation, or mechanical inj...

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Bibliographic Details
Published in:Case reports in infectious diseases Vol. 2016; no. 2016; pp. 1 - 5
Main Authors: Ahmadinejad, Zahra, Alimadadi, Hosein, Gharagozlou, Mohammd, Gharib, Behdad, Memarian, Sara, Ziaee, Vahid
Format: Journal Article
Language:English
Published: Cairo, Egypt Hindawi Publishing Corporation 01-01-2016
John Wiley & Sons, Inc
Hindawi Limited
Subjects:
Care and treatment
Case Report
Complications and side effects
Dermatitis
Development and progression
Iatrogenic diseases
Inflammation
Penicillin
Skin
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Summary:Nicolau syndrome (NS) or livedo-like dermatitis is a rare complication of injection of various medications such as penicillin. The pathophysiology of this events is not clear, but some hypotheses are suggested, such as sympathetic nerve stimulation, embolic occlusion, inflammation, or mechanical injury. In this paper we report 3 cases of NS following benzathine penicillin. Clinical symptoms improved in 2 cases during 2-month follow-up, but one of them had a residual necrosis in the distal phalanges of the toes.
Bibliography:ObjectType-Article-1
SourceType-Scholarly Journals-1
ObjectType-Feature-2
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Academic Editor: Tomoyuki Shibata
ISSN:2090-6625
2090-6633
DOI:10.1155/2016/9082158