Search Results - "Ghannam, Ameen F"

Prescribing Patterns of Proprotein Convertase Subtilisin-Kexin Type 9 Inhibitors in Eligible Patients With Clinical Atherosclerotic Cardiovascular Disease or Heterozygous Familial Hypercholesterolemia by Karalis, Dean G., Mallya, Usha G., Ghannam, Ameen F., Elassal, Joseph, Gupta, Rishab, Boklage, Susan H.

“…Two proprotein convertase subtilisin-kexin type 9 (PCSK9) inhibitors are approved for patients with atherosclerotic cardiovascular disease or heterozygous…”
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1080-P: Addressing the Safety Challenges of Aldose Reductase Inhibition: Development of AT-001 for Diabetic Cardiomyopathy, a Potent and Selective Next Generation Aldose Reductase Inhibitor by PERFETTI, RICCARDO, YEPURI, GAUTHAM, QUADRI, NOSIRUDEEN A., GHANNAM, AMEEN F., RAMASAMY, RAVICHANDRAN, SHENDELMAN, SHOSHANA

“…Diabetic Cardiomyopathy (DbCM) leading to overt heart failure is a common sequelae of both type 1 and type 2 diabetes. Prior attempts to develop treatments for…”
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462-P: AT-001, a Next Generation Aldose Reductase Inhibitor with Improved Selectivity and Specificity, Protects from Cellular Damage Associated with Hyperglycemia by PERFETTI, RICCARDO, YEPURI, GAUTHAM, QUADRI, NOSIRUDEEN A., RAMASAMY, RAVICHANDRAN, GHANNAM, AMEEN F., SHENDELMAN, SHOSHANA

“…The generation of Reactive Oxygen Species (ROS) and Advanced Glycation Endproducts (AGE’s) resulting from chronic tissue exposure to elevated levels of glucose…”
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186-OR: Safety and Tolerability of the Next Generation Aldose Reductase Inhibitor (ARI) AT-001 Supports Initiation of the Pivotal Trial in Diabetic Cardiomyopathy (DbCM) by PERFETTI, RICCARDO, LAWSON, FRANCESCA C., ROSENSTOCK, JULIO, JANUZZI, JAMES, SHENDELMAN, SHOSHANA, WANG, STELLA, GHANNAM, AMEEN F.

“…The role of Aldose Reductase in diabetes complications, including DbCM is well established. Older generation ARIs were unsuccessful due to lack of selectivity,…”
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UNDERSTANDING THE PREDICTORS OF ACHIEVING LDL-C TARGETS WHEN ADDING EZETIMIBE IN HIGH RISK PATIENTS by Karalis, Dean, Mallya, Usha, Elassal, Joseph, Ghannam, Ameen F, Gupta, Rishab, Boklage, Susan

“…Background: In March 2016, the ACC released their Expert Consensus Decision Pathway which provided additional guidance on the use of non-statin treatment (tx)…”
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Furanone synthesis via an electrophilic capped carbonyl ylide by Linderman, Russell J, Graves, David M, Kwochka, William R, Ghannam, Ameen F, Anklekar, T. V

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Abstract 12904: Assessing Low-Density Lipoprotein Cholesterol Risk in Secondary Prevention Patients Within The PINNACLE National Outpatient Registry by Allen, Joseph M, Arnold, Suzanne V, Lohr, Nicole L, Reisman, Lonny, Ghannam, Ameen F, Sanganalmath, Santosh K, Khan, Irfan, Iorga, Serban, Kumbhani, Dharam

“…IntroductionContemporary patterns of low density lipoprotein cholesterol (LDL-C) goal achievement and lipid-lowering strategies in cardiology or primary care…”
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