Search Results - "Ghannadan, M."
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Detection of differentiation‐ and activation‐linked cell surface antigens on cultured mast cell progenitors
Published in Allergy (Copenhagen) (01-10-2005)“…Background: Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34+ hemopoietic progenitor cells (HPC)…”
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2
Effects of various statins on cytokine‐dependent growth and IgE‐dependent release of histamine in human mast cells
Published in Allergy (Copenhagen) (01-03-2006)“…Background: Statins are inhibitors of hydroxymethylglutaryl coenzyme A (HMG CoA) reductase, a key enzyme in mevalonic acid (MVA)‐dependent signaling. Recent…”
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On the way to targeted therapy of mast cell neoplasms: identification of molecular targets in neoplastic mast cells and evaluation of arising treatment concepts
Published in European journal of clinical investigation (01-08-2004)“…Several emerging treatment concepts for myeloid neoplasms are based on novel drugs targeting cell surface antigens, signalling pathways, or critical effector…”
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4
A Human Monoclonal IgE Antibody Defines a Highly Allergenic Fragment of the Major Timothy Grass Pollen Allergen, Phl p 5: Molecular, Immunological, and Structural Characterization of the Epitope-Containing Domain
Published in The Journal of immunology (1950) (01-10-2000)“…Almost 90% of grass pollen-allergic patients are sensitized against group 5 grass pollen allergens. We isolated a monoclonal human IgE Fab out of a…”
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5
Prevention of latex allergy by selection of low-allergen gloves
Published in Clinical and experimental allergy (01-04-2000)“…Background In recent years the prevalence of type I allergy to latex has continuously increased, in particular among healthcare workers, to about 10%. While…”
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6
Liquid hydrocarbon-absorbents, 1: Preparation and evaluation of styrenic absorbents for liquid aromatic hydrocarbons
Published in International journal of polymeric materials (01-01-2003)“…Bulk, Solution, and suspension methods were used to radically polymerize styrene/ethyleneglycol dimethacrylate for obtaining liquid aromatic…”
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7
Primary sources and immunological prerequisites for sST2 secretion in humans
Published in Cardiovascular research (01-09-2010)“…Aims Serum levels of the soluble growth stimulation gene-2 (sST2) are elevated in heart and pulmonary diseases. However, the relationship of the…”
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8
Quantitative, phenotypic, and functional evaluation of basophils in myelodysplastic syndromes
Published in European journal of clinical investigation (01-10-2001)“…Background The myelodysplastic syndromes (MDS) are a group of clonal haematological disorders characterized by cytopenia(s), reduced differentiation‐capacity…”
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9
Fos and Jun Proteins Are Specifically Expressed During Differentiation of Human Keratinocytes
Published in Journal of investigative dermatology (01-01-2005)“…Activator protein 1 (AP-1) proteins play key roles in the regulation of cell proliferation and differentiation. In this study we investigated the expression of…”
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10
Recombinant allergens promote expression of CD203c on basophils in sensitized individuals
Published in Journal of allergy and clinical immunology (01-07-2002)“…Background: Traditionally, the diagnosis of type I allergies is based on clinical data, skin test results, and laboratory test results with allergen extracts…”
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11
C5a stimulates production of plasminogen activator inhibitor-1 in human mast cells and basophils
Published in Blood (15-07-2002)“…We have recently shown that resting human mast cells (MCs) produce tissue-type plasminogen activator (t-PA) without simultaneously expressing plasminogen…”
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12
Stratum corneum-derived caspase-14 is catalytically active
Published in FEBS letters (19-11-2004)“…Caspase-14, a cysteine protease with restricted tissue distribution, is highly expressed in differentiated epidermal keratinocytes. Here, we extracted soluble…”
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Caspase-14 but not caspase-3 is processed during the development of fetal mouse epidermis
Published in Differentiation (London) (01-10-2005)“…The activation of caspases is a central step in apoptosis and may also be critical for terminal differentiation of epidermal keratinocytes (KC). In particular,…”
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14
Detection of novel CD antigens on the surface of human mast cells and basophils
Published in International archives of allergy and immunology (01-04-2002)“…Mast cells (MC) and basophils are effector cells of allergic reactions. Growth and function of these cells are regulated by a network of cytokines, other…”
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15
Phenotypic Characterization of Human Skin Mast Cells by Combined Staining with Toluidine Blue and CD Antibodies
Published in Journal of investigative dermatology (01-10-1998)“…Mast cells (MC) are important cellular components of the immune network in diverse organs. The skin MC has likewise been implicated in IgE- and…”
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16
Immunohistochemical detection of VEGF in the bone marrow of patients with acute myeloid leukemia: Correlation between VEGF expression and the FAB category
Published in American journal of clinical pathology (01-05-2003)“…We studied vascular endothelial growth factor (VEGF) expression in bone marrow sections obtained from 3 healthy donors and 41 patients with acute myeloid…”
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17
Cell surface membrane antigen phenotype of human gastrointestinal mast cells
Published in International Archives of Allergy and Immunology (01-10-2005)“…Mast cells (MC) are important effector cells of allergic and inflammatory reactions in diverse organs. These cells interact with a number of other immune cells…”
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Expression, epitope analysis, and functional role of the LFA-2 antigen detectable on neoplastic mast cells
Published in Blood (15-12-2001)“…Recent data suggest that mast cells (MCs) in patients with systemic mastocytosis or mast cell leukemia express a CD2-reactive antigen. To explore the…”
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Expression of homing receptors and related molecules on human mast cells and basophils: a comparative analysis using multi-color flow cytometry and toluidine blue/immunofluorescence staining techniques
Published in Tissue antigens (01-11-1999)“…Mast cells (MC) and blood basophils (Ba) are multifunctional effector cells of the immune system and accumulate in areas of ongoing disease. However, despite…”
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Original article: Detection of differentiation- and activation-linked cell surface antigens on cultured mast cell progenitors
Published in Allergy (Copenhagen) (01-10-2005)“…Mast cells (MC) are multifunctional effector cells of the immune system. They derive from uncommitted CD34+ hemopoietic progenitor cells (HPC). Depending on…”
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