Search Results - "Ghanjati, Foued"
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Bortezomib/proteasome inhibitor triggers both apoptosis and autophagy-dependent pathways in melanoma cells
Published in Cellular signalling (01-01-2013)“…Generally, both endoplasmic reticulum (ER) stress and mitochondrial dysregulation are a potential therapeutic target of anticancer agents including bortezomib…”
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Induced Pluripotent Stem Cells to Model Juvenile Myelomonocytic Leukemia: New Perspectives for Preclinical Research
Published in Cells (Basel, Switzerland) (06-09-2021)“…Juvenile myelomonocytic leukemia (JMML) is a malignant myeloproliferative disorder arising in infants and young children. The origin of this neoplasm is…”
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IDLN-MSP: Idiolocal normalization of real-time methylation-specific PCR for genetic imbalanced DNA specimens
Published in BioTechniques (01-02-2016)“…Sensitive, accurate, and reliable measurements of tumor cell-specific DNA methylation changes are of fundamental importance in cancer diagnosis, prognosis, and…”
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THE INTERFACE OF EPIGENETICS AND ENERGY METABOLISM IN JUVENILE MYELOMONOCYTIC LEUKEMIA
Published in EJC paediatric oncology (01-12-2023)Get full text
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Erythroid differentiation of human induced pluripotent stem cells is independent of donor cell type of origin
Published in Haematologica (Roma) (01-01-2015)“…Epigenetic memory in induced pluripotent stem cells, which is related to the somatic cell type of origin of the stem cells, might lead to variations in the…”
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Effect on Multipotency and Phenotypic Transition of Unrestricted Somatic Stem Cells from Human Umbilical Cord Blood after Treatment with Epigenetic Agents
Published in Stem cells international (01-01-2016)“…The epigenetic mechanism of DNA methylation is of central importance for cellular differentiation processes. Unrestricted somatic stem cells (USSCs) from human…”
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Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis
Published in Scientific reports (22-02-2018)“…Urothelial carcinoma (UC), the most common cancer of the urinary bladder causes severe morbidity and mortality, e.g. about 40.000 deaths in the EU annually,…”
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Epigenetic modifications of gene promoter DNA in the liver of adult female mice masculinized by testosterone
Published in The Journal of steroid biochemistry and molecular biology (01-01-2015)“…•Epigenetic reprogramming by testosterone (T) of promoter gene DNA in the liver of female mice.•T induces long-lasting hyper- and hypo-methylations of DNA of…”
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Origin-Dependent Neural Cell Identities in Differentiated Human iPSCs In Vitro and after Transplantation into the Mouse Brain
Published in Cell reports (Cambridge) (25-09-2014)“…The differentiation capability of induced pluripotent stem cells (iPSCs) toward certain cell types for disease modeling and drug screening assays might be…”
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Unreserved application of epigenetic methods to define differences of DNA methylation between urinary cellular and cell-free DNA
Published in Cancer biomarkers : section A of Disease markers (01-01-2014)“…Urinary DNA is increasingly gaining importance in diagnosis of urological malignancies. Especially cell-free DNA originating from apoptotic and necrotic cells…”
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ILLUSTRATION OF CLONAL ARCHITECTURE IN JUVENILE MYELOMONOCYTIC LEUKEMIA BY TARGETED SINGLE-CELL DNA SEQUENCING
Published in EJC paediatric oncology (01-12-2023)Get full text
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IDENTIFICATION OF HIGH-RISK JMML BY BMP4 BISULFITE NEXT-GENERATION SEQUENCING
Published in EJC paediatric oncology (01-12-2023)Get full text
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Protective vaccination and blood-stage malaria modify DNA methylation of gene promoters in the liver of Balb/c mice
Published in Parasitology research (1987) (01-05-2017)“…Epigenetic mechanisms such as DNA methylation are increasingly recognized to be critical for vaccination efficacy and outcome of different infectious diseases,…”
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Author Correction: Aberrant methylated key genes of methyl group metabolism within the molecular etiology of urothelial carcinogenesis
Published in Scientific reports (11-04-2018)“…A correction to this article has been published and is linked from the HTML and PDF versions of this paper. The error has been fixed in the paper…”
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Vinblastine-induced apoptosis of melanoma cells is mediated by Ras homologous A protein (Rho A) via mitochondrial and non-mitochondrial-dependent mechanisms
Published in Apoptosis (London) (01-08-2013)“…Despite the availability of melanoma treatment at the primary site, the recurrence of local melanoma can metastasize to any distant organ. Currently, the…”
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Unrestricted somatic stem cells (USSC) from human umbilical cord blood display uncommitted epigenetic signatures of the major stem cell pluripotency genes
Published in Stem cell research (01-01-2011)“…Unrestricted somatic stem cells (USSC) from human cord blood display a broad differentiation potential for ectodermal, mesodermal, and endodermal cell types…”
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Methods for Separate Isolation of Cell-Free DNA and Cellular DNA from Urine-Application of Methylation-Specific PCR on both DNA Fractions
Published in The open biomarkers journal (02-12-2011)“…The analysis of genomic DNA is widely-used for research, forensic and diagnostic purposes. Here we describe reliable methods for isolation of cell-free DNA and…”
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