Search Results - "Ghandour, Said"

The neural androgen receptor: a therapeutic target for myelin repair in chronic demyelination by HUSSAIN, Rashad, GHOUMARI, Abdel M, TRONCHE, François, SITRUK-WARE, Regine, SCHUMACHER, Michael, SAID GHANDOUR, M, BIELECKI, Bartosz, STEIBEL, Jérôme, BOEHM, Nelly, LIERE, Philippe, MACKLIN, Wendy B, KUMAR, Narender, HABERT, René, MHAOUTY-KODJA, Sakina

“…Myelin regeneration is a major therapeutic goal in demyelinating diseases, and the failure to remyelinate rapidly has profound consequences for the health of…”
Get full text

Unexpected central role of the androgen receptor in the spontaneous regeneration of myelin by Bielecki, Bartosz, Mattern, Claudia, Ghoumari, Abdel M., Javaid, Sumaira, Smietanka, Kaja, Ghanem, Charly Abi, Mhaouty-Kodja, Sakina, Ghandour, M. Said, Baulieu, Etienne-Emile, Franklin, Robin J. M., Schumacher, Michael, Traiffort, Elisabeth

“…Lost myelin can be replaced after injury or during demyelinating diseases in a regenerative process called remyelination. In the central nervous system (CNS),…”
Get full text

Mammalian-Specific Central Myelin Protein Opalin Is Redundant for Normal Myelination: Structural and Behavioral Assessments by Yoshikawa, Fumio, Sato, Yumi, Tohyama, Koujiro, Akagi, Takumi, Furuse, Tamio, Sadakata, Tetsushi, Tanaka, Mika, Shinoda, Yo, Hashikawa, Tsutomu, Itohara, Shigeyoshi, Sano, Yoshitake, Ghandour, M Said, Wakana, Shigeharu, Furuichi, Teiichi

“…Opalin, a central nervous system-specific myelin protein phylogenetically unique to mammals, has been suggested to play a role in mammalian-specific myelin. To…”
Get full text

Oligodendroglial primary cilium heterogeneity during development and demyelination/remyelination by Delfino, Giada, Bénardais, Karelle, Graff, Julien, Samama, Brigitte, Antal, Maria Cristina, Ghandour, M Said, Boehm, Nelly

“…The primary cilium (PC) has emerged as an indispensable cellular antenna essential for signal transduction of important cell signaling pathways. The rapid…”
Get full text

25-hydroxycholesterol provokes oligodendrocyte cell line apoptosis and stimulates the secreted phospholipase A2 type IIA via LXR beta and PXR by Trousson, Amalia, Bernard, Sophie, Petit, Patrice X, Liere, Philippe, Pianos, Antoine, El Hadri, Khadija, Lobaccaro, Jean-Marc A, Said Ghandour, M, Raymondjean, Michel, Schumacher, Michael, Massaad, Charbel

“…In several neurodegenerative diseases of the CNS, oligodendrocytes are implicated in an inflammatory process associated with altered levels of oxysterols and…”
Get full text

Recovery from Chronic Demyelination by Thyroid Hormone Therapy: Myelinogenesis Induction and Assessment by Diffusion Tensor Magnetic Resonance Imaging by Harsan, Laura-Adela, Steibel, Jerome, Zaremba, Anita, Agin, Arnaud, Sapin, Remy, Poulet, Patrick, Guignard, Blandine, Parizel, Nathalie, Grucker, Daniel, Boehm, Nelly, Miller, Robert H, Ghandour, M. Said

“…The failure of the remyelination processes in multiple sclerosis contributes to the formation of chronic demyelinated plaques that lead to severe neurological…”
Get full text

Adenylate Cyclase Type III Is Not a Ubiquitous Marker for All Primary Cilia during Development by Antal, Maria Cristina, Bénardais, Karelle, Samama, Brigitte, Auger, Cyril, Schini-Kerth, Valérie, Ghandour, Said, Boehm, Nelly

“…Adenylate cyclase type III (AC3) is localized in plasma membrane of neuronal primary cilium and can be used as a marker of this cilium. AC3 has also been…”
Get full text

Brain dysmyelination and recovery assessment by noninvasive in vivo diffusion tensor magnetic resonance imaging by Harsan, Laura A., Poulet, Patrick, Guignard, Blandine, Steibel, Jérôme, Parizel, Nathalie, Loureiro de Sousa, Paulo, Boehm, Nelly, Grucker, Daniel, Ghandour, M. Said

“…Diffusion tensor magnetic resonance imaging (DT‐MRI) was applied for in vivo quantification of myelin loss and regeneration. A transgenic mouse line…”
Get full text

Detection of N‐acetyl methionine in human and murine brain and neuronal and glial derived cell lines by Smith, Tara, Ghandour, M. Said, Wood, Paul L.

“…J. Neurochem. (2011) 118, 187–194. Despite the fact that N‐acetyl methionine (NAM) supplementation has long been reported as a bioavailable source of…”
Get full text

Human Neural Cells Transiently Express Reelin during Olfactory Placode Development by Antal, M Cristina, Samama, Brigitte, Ghandour, M Said, Boehm, Nelly

“…Reelin, an extracellular glycoprotein is essential for migration and correct positioning of neurons during development. Since the olfactory system is known as…”
Get full text

Proliferation and Death of Oligodendrocytes and Myelin Proteins Are Differentially Regulated in Male and Female Rodents by Cerghet, Mirela, Skoff, Robert P, Bessert, Denise, Zhang, Zhan, Mullins, Chadwick, Ghandour, M. Said

“…Sexual dimorphism of neurons and astrocytes has been demonstrated in different centers of the brain, but sexual dimorphism of oligodendrocytes and myelin has…”
Get full text

Peroxisomal and mitochondrial status of two murine oligodendrocytic cell lines (158N, 158JP): potential models for the study of peroxisomal disorders associated with dysmyelination processes by Baarine, Mauhamad, Ragot, Kevin, Genin, Emmanuelle C., El Hajj, Hammam, Trompier, Doriane, Andreoletti, Pierre, Ghandour, M. Said, Menetrier, Franck, Cherkaoui‐Malki, Mustapha, Savary, Stephane, Lizard, Gerard

“…In some neurodegenerative disorders (leukodystrophies) characterized by myelin alterations, the defect of peroxisomal functions on myelin‐producing cells…”
Get full text

Expression pattern of stop lacZ reporter gene in adult and developing mouse brain by Couégnas, Alice, Schweitzer, Annie, Andrieux, Annie, Ghandour, M. Said, Boehm, Nelly

“…Stable tubulin‐only polypeptide (STOP) proteins are microtubule‐associated proteins responsible for microtubule stabilization in neurons. STOP null mice show…”
Get full text

Problems associated with the process of claim management in Palestine: Contractors' perspective by Enshassi, Adnan, Mohamed, Sherif, El‐Ghandour, Said

“…Purpose - During the past few years, only a limited number of construction projects in Palestine were completed on time; indeed many of these projects had been…”
Get full text

Characterisation of spinal cord in a mouse model of spastic paraplegia related to abnormal axono–myelin interactions by in vivo quantitative MRI by Hassen, Wadie Ben, Bégou, Mélina, Traore, Amidou, Moussa, Abdelatif Ben, Boehm, Nelly, Ghandour, M. Said, Renou, Jean-Pierre, Boespflug-Tanguy, Odile, Bonny, Jean-Marie

“…In inherited neurodegenerative disorders the engineering of genetically modified mice for the causative genes have provided new insights in the understanding…”
Get full text

HIV-1 Tat disrupts blood-brain barrier integrity and increases phagocytic perivascular macrophages and microglia in the dorsal striatum of transgenic mice by Leibrand, Crystal R., Paris, Jason J., Ghandour, M. Said, Knapp, Pamela E., Kim, Woong-Ki, Hauser, Kurt F., McRae, MaryPeace

“…•HIV-1 Tat exposure disrupted the BBB, as evidenced by Na-F and HRP leakage into the brain.•HIV-1 Tat exposure increased phagocytic macrophages/microglia…”
Get full text

Short interfering RNA‐induced gene silencing is transmitted between cells from the mammalian central nervous system by Zhao, Tian‐Yong, Zou, Shi‐Ping, Alimova, Yelena V., Wang, Guoying, Hauser, Kurt F., Ghandour, M. Said, Knapp, Pamela E.

“…Although short interfering RNA (siRNA)‐induced gene silencing can be transmitted between cells in plants and in Caenorhabditis elegans, this phenomenon has…”
Get full text

Recovery of Myelin after Induction of Oligodendrocyte Cell Death in Postnatal Brain by Jalabi, Walid, Boehm, Nelly, Grucker, Daniel, Ghandour, M. Said

“…A transgenic mouse line (Oligo-TTK) was established to monitor oligodendrocyte cell death and myelin formation in the CNS. The expression of a conditionally…”
Get full text

An immortalized jimpy oligodendrocyte cell line: Defects in cell cycle and cAMP pathway by Feutz, Anne Catherine, Pham-Dinh, Danielle, Allinquant, Bernadette, Miehe, Monique, Ghandour, M. Said

“…Normal and jimpy oligodendrocytes in secondary cultures were transfected with plasmids containing the SV40 T‐antigen gene expressed under the control of the…”
Get full text

New insights on neuronal alterations in jimpy mutant brain by Harsan, Laura, Jalabi, Walid, Grucker, Daniel, Ghandour, M Said

“…In spite of abundant data on oligodendrocyte abnormalities in dysmyelinated jimpy brain, little is known about the axonal damage and the expression of neuronal…”
Get full text