Search Results - "Ghanavatinejad, Alireza"
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Endometrial mesenchymal stem/stromal cells: The Enigma to code messages for generation of functionally active regulatory T cells
Published in Stem cell research & therapy (09-10-2021)“…Abstract Background Regulatory T cells (Tregs) play an important role in fine-tuning of immune responses and are pivotal for a successful pregnancy. Recently,…”
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MicroRNAs Targeting Programmed Cell Death Protein 1 (PD-1) Promote Natural Killer Cell Exhaustion in Rheumatoid Arthritis
Published in Iranian journal of allergy, asthma, and immunology (01-12-2022)“… Natural killer (NK) cells play a role in the pathogenesis of rheumatoid arthritis (RA). Upregulated levels of programmed cell death protein 1 (PD-1) is a sign…”
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Decrease of Tumor-infiltrating Regulatory T Cells Using Pentoxifylline: An Ex Vivo Analysis in Triple-negative Breast Cancer Mouse Model
Published in Iranian journal of allergy, asthma, and immunology (01-04-2022)“…Triple-negative breast cancer (TNBC) is the most aggressive type of BC with the highest percentage of tumor-infiltrating lymphocytes (TILs). Hence, TIL therapy…”
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Blockade of exosome release alters HER2 trafficking to the plasma membrane and gives a boost to Trastuzumab
Published in Clinical & translational oncology (01-01-2023)“…Objective(s) Exosomal HER2 has been evidenced to interfere with antibody-induced anti-tumor effects. However, whether the blockade of HER2+ exosomes release…”
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MneSCs exert a supportive role in establishing a pregnancy-friendly microenvironment by inhibiting TH17 polarization
Published in Journal of reproductive immunology (01-04-2021)“…Uncontrolled TH17 differentiation has been suggested to play a role in the pathogenesis of pregnancy loss. We recently showed that menstrual blood stromal/stem…”
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Human menstrual blood-derived stromal/stem cells modulate functional features of natural killer cells
Published in Scientific reports (10-07-2019)“…Although natural killer (NK) cells play a crucial role in the maintenance of a successful pregnancy, their cytotoxic activity should be tightly controlled. We…”
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Sciatic nerve regeneration by transplantation of menstrual blood-derived stem cells
Published in Molecular biology reports (01-10-2017)“…This is the first study demonstrating the efficacy of menstrual blood-derived stem cell (MenSC) transplantation via a neural guidance conduit, for peripheral…”
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The imbalance of circulating T helper subsets and regulatory T cells in patients with LRBA deficiency: Correlation with disease severity
Published in Journal of cellular physiology (01-11-2018)“…Patients with lipopolysaccharides responsive beige‐like anchor protein (LRBA) deficiency suffer from a variety of immunological abnormalities. In the current…”
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Endoplasmic reticulum aminopeptidase 2 gene single nucleotide polymorphisms in association with susceptibility to ankylosing spondylitis in an Iranian population
Published in Immunology letters (01-07-2020)“…•ERAP2 gene SNPs are not associated with AS risk.•rs2910686 SNP is associated with higher risk of AS in the HLA-B27 positive group.•mRNA expression and serum…”
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MenSCs exert a supportive role in establishing a pregnancy-friendly microenvironment by inhibiting TH17 polarization
Published in Journal of reproductive immunology (01-04-2021)“…•MenSCs downregulate RORC and inhibit T CD4 + TH17 polarization.•MenSCs managed to generate Tregs in a TH17 favored condition.•Inhibition of PGE2 synergize…”
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Pentoxifylline changes the balance of immune cell population in breast tumor-infiltrating lymphocytes
Published in Medical oncology (Northwood, London, England) (06-05-2023)“…Immunotherapy utilizing tumor-infiltrating lymphocytes (TILs) is a promising approach for cancer treatment. Pentoxifylline (PTXF), a xanthine derivative,…”
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Autoimmunity in primary T-cell immunodeficiencies
Published in Expert review of clinical immunology (01-09-2016)“…Primary immunodeficiency diseases (PID) are a genetically heterogeneous group of more than 270 disorders that affect distinct components of both humoral and…”
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Menstrual Blood-Derived Stromal Stem Cells Augment CD4+ T Cells Proliferation
Published in Avicenna journal of medical biotechnology (01-07-2018)“…It is more than sixty years that the concept of the fetal allograft and immunological paradox of pregnancy was proposed and in this context, several regulatory…”
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