Search Results - "Ghaly, Hany"
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The insulinotropic effect of fluoroquinolones
Published in Biochemical pharmacology (15-03-2009)“…Antimicrobial fluoroquinolones induce, with strongly varying frequency, life-threatening hypoglycemias, which is explained by their ability to block K ATP…”
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2
New drug delivery strategies targeting the GnRH receptor in breast and other cancers
Published in Endocrine-related cancer (01-11-2021)“…Cancer is the uncontrolled division of abnormal cells in a specific organ. Globally, about one in six deaths is due to cancer. Despite the plethora of research…”
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Effect of fluoroquinolones on mitochondrial function in pancreatic beta cells
Published in European journal of pharmaceutical sciences (14-02-2014)“…[Display omitted] Hyper- and hypoglycaemias are known side effects of fluoroquinolone antibiotics, resulting in a number of fatalities. Fluoroquinolone-induced…”
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Acute metabolic amplification of insulin secretion in mouse islets is mediated by mitochondrial export of metabolites, but not by mitochondrial energy generation
Published in Metabolism, clinical and experimental (01-10-2013)“…Abstract Objective The β-cell metabolism of glucose and of some other fuels (e.g. α-ketoisocaproate) generates signals triggering and acutely amplifying…”
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5
Studies of first phase insulin secretion using imposed plasma membrane depolarization
Published in Frontiers in bioscience (Scholar edition) (01-01-2011)“…The first phase of glucose-induced insulin secretion is generally regarded to represent the release of a finite pool of secretion-ready granules, triggered by…”
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