Search Results - "Ghalayini, AJ"
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Cholesterol-Dependent Association of Caveolin-1 with the Transducin α Subunit in Bovine Photoreceptor Rod Outer Segments: Disruption by Cyclodextrin and Guanosine 5‘-O-(3-Thiotriphosphate)
Published in Biochemistry (Easton) (08-07-2003)“…Evidence suggests that caveolins, 21−24 kDa cholesterol-binding proteins that generally reside in specialized detergent-resistant membrane microdomains, act as…”
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Light-dependent association of Src with photoreceptor rod outer segment membrane proteins in vivo
Published in The Journal of biological chemistry (11-01-2002)“…In vivo light exposure results in tyrosine phosphorylation of several rod outer segment (ROS) proteins (Ghalayini, A. J., Guo, X. X., Koutz, C. A, and…”
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Activation of Focal Adhesion Kinase in Adenovirus-Infected Human Corneal Fibroblasts
Published in Investigative ophthalmology & visual science (01-08-2002)“…Focal adhesion kinase (FAK), a nonreceptor protein tyrosine kinase with protean downstream influences on cell cycle regulation, cytoskeletal dynamics, and cell…”
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Tyrosine Phosphorylation of the α Subunit of Transducin and Its Association with Src in Photoreceptor Rod Outer Segments
Published in Journal of neurochemistry (01-11-2000)“…: Recent evidence indicates that tyrosine phosphorylation may play important roles in retinal photoreceptor rod outer segments (ROS). We investigated the…”
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Association of the Tyrosine Phosphatase SHP‐2 with Transducin‐α and a 97‐kDa Tyrosine‐Phosphorylated Protein in Photoreceptor Rod Outer Segments
Published in Journal of neurochemistry (01-12-1999)“…: Increasing evidence indicates that tyrosine phosphorylation, controlled by the concerted action of tyrosine kinases and protein tyrosine phosphatases (PTPs),…”
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Light‐Mediated Activation of Diacylglycerol Kinase in Rat and Bovine Rod Outer Segments
Published in Journal of neurochemistry (01-07-2000)“…The hydrolysis of phosphatidylinositol 4,5‐bisphosphate is regulated by light in retinal rod outer segment (ROS) membranes. We recently reported that the…”
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Phosphatidylinositol 3-kinase in bovine photoreceptor rod outer segments
Published in Investigative ophthalmology & visual science (01-08-1997)“…Phosphatidylinositol 3-kinase (PI 3-kinase) plays important roles in mitogenesis, vesicular trafficking, actin rearrangement, and prevention of apoptotic cell…”
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Influence of UVA Light Stress on Photoreceptor Cell Metabolism: Decreased Rates of Rhodopsin Regeneration and Opsin Synthesis
Published in Experimental eye research (01-06-1999)“…There is considerable evidence indicating that rhodopsin is the chromophore mediating light damage to the rat retina caused by exposure to mid-visible…”
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Light stimulates tyrosine phosphorylation of rat rod outer segments in vivo
Published in Experimental eye research (01-06-1998)Get full text
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Activation of bovine rod outer segment phospholipase C by arrestin
Published in The Journal of biological chemistry (05-09-1992)“…Phospholipase C (PLC) enzyme activity in rod outer segment (ROS) membranes bleached in the presence of ATP and GTP was assayed using exogenously added…”
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cDNA sequence and gene locus of the human retinal phosphoinositide-specific phospholipase-C beta 4 (PLCB4)
Published in Genomics (San Diego, Calif.) (01-09-1995)“…Defects in the Drosophila norpA (no receptor potential A) gene encoding a phosphoinositide-specific phospholipase C (PLC) block invertebrate phototransduction…”
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Light adaptation of bovine retinas in situ stimulates phosphatidylinositol synthesis in rod outer segments in vitro
Published in Current eye research (01-11-1995)“…Light-stimulated phosphoinositide turnover has been reported in both vertebrate retina and isolated rod outer segments (ROS). In the current investigation, we…”
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Identification and immunolocalization of phospholipase C in bovine rod outer segments
Published in Journal of neurochemistry (01-10-1991)“…Bovine rod outer segments (ROS) contain a phospholipase C (PLC) that hydrolyzes phosphatidylinositol 4,5-bisphosphate. Approximately 60-70% of PLC activity is…”
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Immunolocalization of PKC zeta in rat photoreceptor inner segments
Published in Current eye research (01-02-1994)“…We have utilized several peptide specific antisera directed against the C-terminals (Wetsel et al, 1992) of several protein kinase C (PKC) isozymes (alpha,…”
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Membrane-associated inositol hexakisphosphate binding in bovine retina
Published in Current eye research (01-09-1995)“…We investigated the InsP6 binding proteins in bovine retinal membranes and rod outer segments (ROS) by radioligand binding assay and western blotting. The…”
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Phosphoinositide metabolism in frog rod outer segments
Published in Experimental eye research (01-08-1990)“…Previous studies have shown that vertebrate rod outer segments (ROS) have a light activated phospholipase C which hydrolyzes…”
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