Search Results - "Ghai, D."

Design of Parasitic and Process-Variation Aware Nano-CMOS RF Circuits: A VCO Case Study by Ghai, D., Mohanty, S.P., Kougianos, E.

“…This paper proposes a novel flow for parasitic and process-variation aware design of radio-frequency integrated circuits (RFICs). A nano-CMOS current-starved…”
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Extrusion-spheronization: process variables and characterization by Sinha, V R, Agrawal, M K, Agarwal, A, Singh, G, Ghai, D

“…Multiparticulate systems have undergone great development in the past decade fueled by the better understanding of their multiple roles as a suitable delivery…”
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A variability tolerant system-on-chip ready nano-CMOS analogue-to-digital converter by Ghai, D., Mohanty, S. P., Kougianos, E.

“…As integrated circuit technologies progress to nanoscale, process variations become relatively large and significantly impact circuit performance. The…”
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Dicarboxylic Acid Dipeptide Neutral Endopeptidase Inhibitors by Ksander, Gary M, Ghai, Raj D, deJesus, Reynalda, Diefenbacher, Clive, Yuan, Andrew, Berry, Carol, Sakane, Yumi, Trapani, Angelo

“…The synthesis of three series of dicarboxylic acid dipeptide neutral endopeptidase 24.11 (NEP) inhibitors is described. In particular, the amino butyramide 21a…”
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Bottom-boosting differential evolution based digital image security analysis by Ghai, D., Tiwari, S., Das, N.N.

“…With the advancements in multimedia applications, many images are transferred over public networks. Therefore, these images are prone to various security…”
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Ortho-Substituted Benzofused Macrocyclic Lactams as Zinc Metalloprotease Inhibitors by Ksander, Gary M, de Jesus, Reynalda, Yuan, Andrew, Ghai, Trapani, A, McMartin, Colin, Bohacek, Regine

“…The design and preparation of ortho-substituted benzofused macrocyclic lactams are described. The benzofused macrocyclic lactams were designed as neutral…”
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Decent work: Concept and indicators by GHAI, Dharam

“…This article explores the meaning of the decent work concept as applied in industrialized countries, developing countries and transition economies. After a…”
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Meta-Substituted Benzofused Macrocyclic Lactams as Zinc Metalloprotease Inhibitors by Ksander, Gary M, de Jesus, Reynalda, Yuan, Andrew, Ghai, Raj D, McMartin, Colin, Bohacek, Regine

“…The design, synthesis, and biochemical profile of meta-substituted benzofused macrocyclic lactams are described. The meta-substituted benzofused macrocyclic…”
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N-Phosphonomethyl Dipeptides and Their Phosphonate Prodrugs, a New Generation of Neutral Endopeptidase (NEP, EC 3.4.24.11) Inhibitors by De Lombaert, Stephane, Erion, Mark D, Tan, Jenny, Blanchard, Louis, El-Chehabi, Lena, Ghai, R. D, Sakane, Yumi, Berry, Carol, Trapani, Angelo J

“…Inhibitors of the zinc protease neutral endopeptidase (NEP, EC 3.4.24.11) offer significant therapeutic interest as antihypertensives due to their ability to…”
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New .alpha.-Thiol Dipeptide Dual Inhibitors of Angiotensin-I-Converting Enzyme and Neutral Endopeptidase EC 3.4.24.11 by Fink, Cynthia A, Qiao, Ying, Berry, Carol J, Sakane, Yumi, Ghai, Rajendra D, Trapani, Angelo J

“…Dual inhibitors of the two zinc metallopeptidases, neutral endopeptidase (NEP, EC 3.4.24.11) and angiotensin-I converting enzyme, have been the focus of much…”
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Antihypertensive and natriuretic effects of CGS 30440, a dual inhibitor of angiotensin-converting enzyme and neutral endopeptidase 24.11 by Chatelain, R E, Ghai, R D, Trapani, A J, Odorico, L M, Dardik, B N, De Lombaert, S, Lappe, R W, Fink, C A

“…Dual angiotensin-converting enzyme (ACE)/neutral endopeptidase (NEP) inhibitors, by decreasing angiotensin-II production and by preventing the degradation of…”
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Degradation of atrial natriuretic factor by kidney cortex membranes. Isolation and characterization of the primary proteolytic product by Koehn, J A, Norman, J A, Jones, B N, LeSueur, L, Sakane, Y, Ghai, R D

“…Synthetic rat atrial natriuretic factor (r-ANF, 1-28) was incubated with rat kidney cortex membranes, and a predominant degradation product was identified by…”
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Identification of protease 3.4.24.11 as the major atrial natriuretic factor degrading enzyme in the rat kidney by Sonnenberg, J L, Sakane, Y, Jeng, A Y, Koehn, J A, Ansell, J A, Wennogle, L P, Ghai, R D

“…We have identified a metalloendoprotease from rat kidney cortex that cleaves the cysteine-phenylalanine bond (Cys7-Phe8) within the 17 amino acid ring…”
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Heterocyclic lactam derivatives as dual angiotensin converting enzyme and neutral endopeptidase 24.11 inhibitors by Stanton, James L, Sperbeck, Donald M, Trapani, Angelo J, Cote, Donald, Sakane, Yumi, Berry, Carol J, Ghai, Rajendra D

“…A series of 13- and 14-membered ring lactam derivatives 9a,b, 10, 11, and 12a-c was prepared from L-cysteine. Compounds 9a,b and 12a,b were tested in vitro for…”
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Design and synthesis of an orally active macrocyclic neutral endopeptidase 24.11 inhibitor by MacPherson, Lawrence J, Bayburt, Erol K, Capparelli, Michael P, Bohacek, Regine S, Clarke, Frank H, Ghai, Rajendra D, Sakane, Yumi, Berry, Carol J, Peppard, Jane V, Trapani, Angelo J

“…A potent macrocyclic inhibitor of neutral endopeptidase (NEP) 24.11 was designed using a computer model of the active site of thermolysin. This 10-membered…”
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Differential structure-activity relationships of phosphoramidon analogues for inhibition of three metalloproteases: endothelin-converting enzyme, neutral endopeptidase, and angiotensin-converting enzyme by Kukkola, P J, Savage, P, Sakane, Y, Berry, J C, Bilci, N A, Ghai, R D, Jeng, A Y

“…The structure-activity relationships of phosphoramidon analogues for inhibition of endothelin-converting enzyme (ECE), neutral endopeptidase 24.11 (NEP), and…”
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EFFECTS OF A NEUTRAL ENDOPROTEASE ENZYME INHIBITOR, THIORPHAN, ON HEMODYNAMICS AND RENAL EXCRETORY FUNCTION IN FOUR MODELS OF EXPERIMENTAL HYPERTENSION by Pamnani, Motilal B., Chen, Shanwan, Bryant, Howard J., Schooley, James F., Haddy, Francis J., Ghai, Raj D.

“…Thiorphan, a neutral endoprotease (NEP) enzyme inhibitor, has been shown to enhance the effects of atrial natriuretic peptide (ANP) in vivo. In this study, we…”
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Pharmacologic profile of CGS 24128, a potent, long-acting inhibitor of neutral endopeptidase 24.11 by Trapani, A J, Beil, M E, Coté, D T, de Lombaert, S, Erion, M D, Gerlock, T E, Ghai, R D, Hopkins, M F, Peppard, J V, Webb, R L

“…We compared the pharmacologic profiles of thiorphan, a neutral endopeptidase (NEP) inhibitor which is cleared rapidly from the circulation, and CGS 24128, an…”
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RP-HPLC Stability-Indicating Assay Method for Talinolol and Characterization of its Degradation Products by Sinha, V.R., Ghai, Damanjeet

“…A reversed-phase high-performance liquid Chromatographic method is developed and validated for the quantitative determination of talinolol and to characterize…”
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Dopaminergic mediation of the diuretic and natriuretic effects of ANF in the rat by Webb, R L, Della Puca, R, Manniello, J, Robson, R D, Zimmerman, M B, Ghai, R D

“…Atrial natriuretic factor (ANF) increases sodium (Na+) and water excretion 8-10 fold on repeated administration to anesthetized rats. SCH-23390 (80…”
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