Search Results - "Ghaffari, Mohammad A."

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  1. 1

    Inhibition of enzyme activity of and cell-mediated substrate cleavage by membrane type 1 matrix metalloproteinase by newly developed mercaptosulphide inhibitors by Hurst, Douglas R, Schwartz, Martin A, Jin, Yonghao, Ghaffari, Mohammad A, Kozarekar, Pallavi, Cao, Jian, Sang, Qing-Xiang Amy

    Published in Biochemical journal (15-12-2005)
    “…MT1-MMP (membrane type 1 matrix metalloproteinase, or MMP-14) is a key enzyme in molecular carcinogenesis, tumour-cell growth, invasion and angiogenesis. Novel…”
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    Journal Article
  2. 2

    Synthesis of N-Substituted Carbonylamino-1,2,3,6-tetrahydropyridines as Potential Anti-Inflammatory Agents by Ghaffari, Mohammad A., Ardley, Tiffany W., Gangapuram, Madhavi, Redda, Kinfe K.

    Published in Synthetic communications (01-01-2011)
    “…Several N-substituted carbonyl/sulfonylamino-1,2,3,6-tetrahydropyridines (5a-i and 9a, b) were synthesized via sodium borohydride reduction of the…”
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  3. 3

    Catalytic- and ecto-domains of membrane type 1-matrix metalloproteinase have similar inhibition profiles but distinct endopeptidase activities by Hurst, Douglas R, Schwartz, Martin A, Ghaffari, Mohammad A, Jin, Yonghao, Tschesche, Harald, Fields, Gregg B, Sang, Qing-Xiang Amy

    Published in Biochemical journal (01-02-2004)
    “…Membrane type 1-matrix metalloproteinase (MT1-MMP/MMP-14) is a major collagenolytic enzyme that plays a vital role in development and morphogenesis. To…”
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  4. 4

    A practical synthesis of differentially-protected cis-1,2-cyclopentanedithiols and cis-3,4-pyrrolidinedithiols by Jin, Yonghao, Ghaffari, Mohammad A, Schwartz, Martin A

    Published in Tetrahedron letters (07-10-2002)
    “…A practical method for the synthesis of cis-1,2-cyclopentanedithiols and cis-3,4-pyrrolidinedithiols with differentially protected sulfurs, needed for the…”
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  5. 5
  6. 6

    Abstract 2515: Synthesis of substituted chromone-2-phenylcarboxamides as anti-breast cancer agents by Redda, Kinfe Ken, Gangapuram, Madhavi, Ghaffari, Mohammad A., Eyunni, Suresh

    Published in Cancer research (Chicago, Ill.) (01-10-2014)
    “…Abstract Breast cancer is one of the most commonly diagnosed cancers and causes the second leading cancer deaths in women. The overall survival rate of breast…”
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  7. 7

    Abstract 2229: Synthesis of heterocyclic compounds as anticancer agents by Redda, Kinfe Ken, Gangapuram, Madhavi, Ghaffari, Mohammad A., Eyunni, Suresh, Mateeva, Nelly, Mochona, Bereket

    Published in Cancer research (Chicago, Ill.) (15-04-2013)
    “…Abstract Cancer is a very complex disease, linked with different initiating causes, cofactors and promoters, and several types of cellular damages. There is a…”
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  8. 8

    New Thiol and Sulfodiimine Metalloproteinase Inhibitors and Their Effect on Human Microvascular Endothelial Cell Growth by Sang, Qing-Xiang Amy, Jia, Meng-Chun, Schwartz, Martin A., Jaye, Michael C., Kleinman, Hynda K., Ghaffari, Mohammad A., Luo, Yi-Lin

    “…Matrix metalloproteinases (MMPs, matrixins) are a family of homologous zinc endopeptidases that may play a very important role in many physiological and…”
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  9. 9

    Relationship between Urbanization and Cancer Incidence in Iran Using Quantile Regression by Momenyan, Somayeh, Sadeghifar, Majid, Sarvi, Fatemeh, Khodadost, Mahmoud, Mosavi-Jarrahi, Alireza, Ghaffari, Mohammad Ebrahim, Sekhavati, Eghbal

    “…Quantile regression is an efficient method for predicting and estimating the relationship between explanatory variables and percentile points of the response…”
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