Search Results - "Ghadially, Ruby"

Clinical presentation of Fibroepithelioma of Pinkus: systematic review of the literature by Kim, Richard W., North, Jeffery P., Ghadially, Ruby

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Transcriptional Programming of Normal and Inflamed Human Epidermis at Single-Cell Resolution by Cheng, Jeffrey B., Sedgewick, Andrew J., Finnegan, Alex I., Harirchian, Paymann, Lee, Jerry, Kwon, Sunjong, Fassett, Marlys S., Golovato, Justin, Gray, Matthew, Ghadially, Ruby, Liao, Wilson, Perez White, Bethany E., Mauro, Theodora M., Mully, Thaddeus, Kim, Esther A., Sbitany, Hani, Neuhaus, Isaac M., Grekin, Roy C., Yu, Siegrid S., Gray, Joe W., Purdom, Elizabeth, Paus, Ralf, Vaske, Charles J., Benz, Stephen C., Song, Jun S., Cho, Raymond J.

“…Perturbations in the transcriptional programs specifying epidermal differentiation cause diverse skin pathologies ranging from impaired barrier function to…”
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Short cell cycle duration is a phenotype of human epidermal stem cells by Xiao, Tong, Eze, Ugomma C, Charruyer-Reinwald, Alex, Weisenberger, Tracy, Khalifa, Ayman, Abegaze, Brook, Schwab, Gabrielle K, Elsabagh, Rasha H, Parenteau, T Richard, Kochanowski, Karl, Piper, Merisa, Xia, Yumin, Cheng, Jeffrey B, Cho, Raymond J, Ghadially, Ruby

“…A traditional view is that stem cells (SCs) divide slowly. Meanwhile, both embryonic and pluripotent SCs display a shorter cell cycle duration (CCD) in…”
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Transit-Amplifying Cell Frequency and Cell Cycle Kinetics Are Altered in Aged Epidermis by Charruyer, Alexandra, Barland, Chantal O., Yue, Lili, Wessendorf, Heike B., Lu, Ying, Jeffrey Lawrence, H., Mancianti, Maria L., Ghadially, Ruby

“…Aged epidermis is less proliferative than young, as exemplified by slower wound healing. However, it is not known whether quantitative and/or qualitative…”
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Facial psoriasis in a mask-like distribution by Zachary, Cameron M.B., Belzer, Annika, Fackler, Nathan P., Shiu, Jessica, Smith, Janellen, Ghadially, Ruby

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25 Years of Epidermal Stem Cell Research by Ghadially, Ruby

“…This is a chronicle of concepts in the field of epidermal stem cell biology and a historic look at their development over time. The past 25 years have seen the…”
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Single-Cell Profiling Reveals Divergent, Globally Patterned Immune Responses in Murine Skin Inflammation by Liu, Yale, Cook, Christopher, Sedgewick, Andrew J., Zhang, Shuyi, Fassett, Marlys S., Ricardo-Gonzalez, Roberto R., Harirchian, Paymann, Kashem, Sakeen W., Hanakawa, Sho, Leistico, Jacob R., North, Jeffrey P., Taylor, Mark A., Zhang, Wei, Man, Mao-Qiang, Charruyer, Alexandra, Beliakova-Bethell, Nadejda, Benz, Stephen C., Ghadially, Ruby, Mauro, Theodora M., Kaplan, Daniel H., Kabashima, Kenji, Choi, Jaehyuk, Song, Jun S., Cho, Raymond J., Cheng, Jeffrey B.

“…Inflammatory response heterogeneity has impeded high-resolution dissection of diverse immune cell populations during activation. We characterize mouse…”
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Optimal ratios of topical stratum corneum lipids improve barrier recovery in chronologically aged skin by Zettersten, Elizabeth M., Ghadially, Ruby, Feingold, Kenneth R., Crumrine, Debra, Elias, Peter M.

“…Background: Chronologically aged skin exhibits delayed recovery rates after defined barrier insults, with decreased epidermal lipid synthesis, and particularly…”
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Influence of pH on Skin Stem Cells and Their Differentiation by Charruyer, Alexandra, Ghadially, Ruby

“…Intracellular pH influences proliferation and differentiation in a range of stem-like and progenitor cells, including embryonic stem cells, induced pluripotent…”
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Effects of petrolatum on stratum corneum structure and function by Ghadially, R, Halkier-Sorensen, L, Elias, P M

“…Ointments (e.g., petrolatum) are thought to be occlusive, thereby blocking transcutaneous water loss and trapping water under the skin's surface. If this…”
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The role of stem and circulating cells in cancer metastasis by Ghadially, Ruby

“…While many solid tumors have been reported to contain stem cell‐like cells termed cancer stem cells, the case for a melanoma stem cell has been debated over…”
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Recessive x-Linked Ichthyosis: Role of Cholesterol-Sulfate Accumulation in the Barrier Abnormality by Zettersten, Elizabeth, Man, Mao-Qiang, Farrell, Angela, Ghadially, Ruby, Williams, Mary L., Feingold, Kenneth R., Elias, Peter M., Sato, Junko, Denda, Mitsuhiro

“…Cholesterol sulfate is a multifunctional sterol metabolite, produced in large amounts in squamous keratinizing epithelia. Because patients with recessive…”
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25 YEARS OF EPIDERMAL STEM CELLS by Ghadially, Ruby

“…This is a chronicle of concepts in the field of epidermal stem cell biology and a historic look at their development over time. The last 25 years have seen the…”
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A new water-based topical carrier with polar skin-lipids by Silvander, Mats, Ringstad, Lovisa, Ghadially, Ruby, Sköld, Thomas

“…A new water-based topical formulation is presented that aims at providing good penetration properties for both lipophilic and hydrophilic drugs with as small a…”
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Decreased Epidermal Lipid Synthesis Accounts for Altered Barrier Function in Aged Mice by Ghadially, Ruby, Brown, Barbara E., Hanley, Karen, Reed, Jeffrey T., Feingold, Kenneth R., Elias, Peter M.

“…The epidermis of aged mice displays decreased stratum corneum (SC) lipid content and decreased extracellular bilayers, which result in impaired barrier…”
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Feroze N. Ghadially - Polymath Extraordinaire by Ghadially, Ruby, Marcus, Peter

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IL-1α, IL-6, and GM-CSF Are Downstream Mediators of IL-17A that Promote Asymmetric Stem Cell Self-Renewal in Human Keratinocytes by Li, Hang, Charruyer, Alex, Weisenberger, Tracy, Khalifa, Ayman, Nguyen, Robert, Ghadially, Ruby

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Membrane Structures in Normal and Essential Fatty Acid-Deficient Stratum Corneum: Characterization by Ruthenium Tetroxide Staining and X-Ray Diffraction by Hou, Sui Yuen E, Mitra, Alok K, White, Stephen H, Menon, Gopinathan K, Ghadially, Ruby, Elias, Peter M

“…Despite the importance of intercellular lamellar bilayers for stratum corneum (SC) barrier function, knowledge about the structure of these bilayers is limited…”
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Genetic priming of sensory neurons in mice that overexpress PAR2 enhances allergen responsiveness by Braz, Joao M., Dembo, Todd, Charruyer, Alexandra, Ghadially, Ruby, Fassett, Marlys S., Basbaum, Allan I.

“…Pruritus is a common symptom of inflammatory skin conditions, including atopic dermatitis (AD). Although primary sensory neurons that transmit pruritic signals…”
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Decreased p53 is associated with a decline in asymmetric stem cell self‐renewal in aged human epidermis by Charruyer, Alexandra, Weisenberger, Tracy, Li, Hang, Khalifa, Ayman, Schroeder, Andrew W., Belzer, Annika, Ghadially, Ruby

“…With age, the epidermis becomes hypoplastic and hypoproliferative. Hypoproliferation due to aging has been associated with decreased stem cell (SC)…”
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