Search Results - "Ghadermarzi, Sina"

flDPnn: Accurate intrinsic disorder prediction with putative propensities of disorder functions by Hu, Gang, Katuwawala, Akila, Wang, Kui, Wu, Zhonghua, Ghadermarzi, Sina, Gao, Jianzhao, Kurgan, Lukasz

“…Identification of intrinsic disorder in proteins relies in large part on computational predictors, which demands that their accuracy should be high. Since…”
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Comparative evaluation of AlphaFold2 and disorder predictors for prediction of intrinsic disorder, disorder content and fully disordered proteins by Zhao, Bi, Ghadermarzi, Sina, Kurgan, Lukasz

“…We expand studies of AlphaFold2 (AF2) in the context of intrinsic disorder prediction by comparing it against a broad selection of 20 accurate, popular and…”
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Sequence-Derived Markers of Drug Targets and Potentially Druggable Human Proteins by Ghadermarzi, Sina, Li, Xingyi, Li, Min, Kurgan, Lukasz

“…Recent research shows that majority of the druggable human proteome is yet to be annotated and explored. Accurate identification of these unexplored druggable…”
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QUARTERplus: Accurate disorder predictions integrated with interpretable residue-level quality assessment scores by Katuwawala, Akila, Ghadermarzi, Sina, Hu, Gang, Wu, Zhonghua, Kurgan, Lukasz

“…A recent advance in the disorder prediction field is the development of the quality assessment (QA) scores. QA scores complement the propensities produced by…”
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Prediction of protein-binding residues: dichotomy of sequence-based methods developed using structured complexes versus disordered proteins by Zhang, Jian, Ghadermarzi, Sina, Kurgan, Lukasz

“…There are over 30 sequence-based predictors of the protein-binding residues (PBRs). They use either structure-annotated or disorder-annotated training…”
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XRRpred: accurate predictor of crystal structure quality from protein sequence by Ghadermarzi, Sina, Krawczyk, Bartosz, Song, Jiangning, Kurgan, Lukasz

“…Abstract Motivation X-ray crystallography was used to produce nearly 90% of protein structures. These efforts were supported by numerous sequence-based tools…”
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DNAgenie: accurate prediction of DNA-type-specific binding residues in protein sequences by Zhang, Jian, Ghadermarzi, Sina, Katuwawala, Akila, Kurgan, Lukasz

“…Efforts to elucidate protein-DNA interactions at the molecular level rely in part on accurate predictions of DNA-binding residues in protein sequences. While…”
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Computational prediction of functions of intrinsically disordered regions by Katuwawala, Akila, Ghadermarzi, Sina, Kurgan, Lukasz

“…Intrinsically disorder regions (IDRs) are abundant in nature, particularly among Eukaryotes. While they facilitate a wide spectrum of cellular functions…”
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Tutorial: a guide for the selection of fast and accurate computational tools for the prediction of intrinsic disorder in proteins by Kurgan, Lukasz, Hu, Gang, Wang, Kui, Ghadermarzi, Sina, Zhao, Bi, Malhis, Nawar, Erdős, Gábor, Gsponer, Jörg, Uversky, Vladimir N., Dosztányi, Zsuzsanna

“…Intrinsic disorder is instrumental for a wide range of protein functions, and its analysis, using computational predictions from primary structures,…”
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CAID prediction portal: a comprehensive service for predicting intrinsic disorder and binding regions in proteins by Del Conte, Alessio, Bouhraoua, Adel, Mehdiabadi, Mahta, Clementel, Damiano, Monzon, Alexander Miguel, Tosatto, Silvio C E, Piovesan, Damiano

“…Abstract Intrinsic disorder (ID) in proteins is well-established in structural biology, with increasing evidence for its involvement in essential biological…”
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Disordered Function Conjunction: On the in-silico function annotation of intrinsically disordered regions by Ghadermarzi, Sina, Katuwawala, Akila, Oldfield, Christopher J, Barik, Amita, Kurgan, Lukasz

“…Intrinsically disorder regions (IDRs) lack a stable structure, yet perform biological functions. The functions of IDRs include mediating interactions with…”
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