Search Results - "Ghader, Babaei"
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EMT, cancer stem cells and autophagy; The three main axes of metastasis
Published in Biomedicine & pharmacotherapy (01-01-2021)“…[Display omitted] •EMT, cancer stem cells and autophagy are the three main axes of cancer cell metastasis.•EMT and cancer stem cells are closely related to…”
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Hsp70 in cancer: A double agent in the battle between survival and death
Published in Journal of cellular physiology (01-05-2021)“…The heat shock protein (Hsps) superfamily, also known as molecular chaperones, are highly conserved and present in all living organisms and play vital roles in…”
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The dual role of mir-146a in metastasis and disease progression
Published in Biomedicine & pharmacotherapy (01-06-2020)“…[Display omitted] •MicroRNAs in cancer cell metastasis by affecting various factors.•mir146a expression were associated with cancer cell metastasis as a dual…”
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A comprehensive review of anticancer mechanisms of action of Alantolactone
Published in Biomedicine & pharmacotherapy (01-04-2021)“…[Display omitted] •Alantolactone increases the level of cellular ROS in cancer cells.•Alantolactone as a pharmacological agent, induced apoptosis in cancer…”
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Exosomes and COVID-19: challenges and opportunities
Published in Comparative clinical pathology (2022)“…Coronavirus disease 2019 or COVID-19, starting from Wuhan, China, in December 2019, is a pandemic situation affecting millions worldwide and has exerted a huge…”
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The role of epithelial-mesenchymal transition in pulmonary fibrosis: lessons from idiopathic pulmonary fibrosis and COVID-19
Published in Cell communication and signaling (13-11-2024)“…Despite the tremendous advancements in the knowledge of the pathophysiology and clinical aspects of SARS-CoV-2 infection, still many issues remain unanswered,…”
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Crosslink between p53 and metastasis: focus on epithelial–mesenchymal transition, cancer stem cell, angiogenesis, autophagy, and anoikis
Published in Molecular biology reports (01-11-2021)“…Introduction P53, as a tumor suppressor gene, is believed to be one of the most mutated genes in cancer cells. The mutant forms of this protein often play a…”
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The emerging role of miR-200 family in metastasis: focus on EMT, CSCs, angiogenesis, and anoikis
Published in Molecular biology reports (01-10-2021)“…Introduction Cancer is the second major threat to human society and one of the main challenges facing healthcare systems. One of the main problems of cancer…”
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Alantolactone and ZnO nanoparticles induce apoptosis activity of cisplatin in an ovarian cancer cell line (SKOV3)
Published in Research in pharmaceutical sciences (01-05-2022)“…Background and purpose: Ovarian cancer is one of the leading causes of cancer mortality in women. Despite the increase in cases of this cancer, the current…”
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Alantolactone triggers oxeiptosis in human ovarian cancer cells via Nrf2 signaling pathway
Published in Biochemistry and biophysics reports (01-09-2023)“…A growing body of evidence indicated that Alantolactone (ALT) promotes Reactive Oxygen Species (ROS) generation exclusively in cancer cells. Therefore, the aim…”
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Critical roles of TLRs on the polarization of mesenchymal stem cells for cell therapy of viral infections: a notice for COVID-19 treatment
Published in Comparative clinical pathology (2021)“…Mesenchymal stem cells (MSCs), as one of the leading cell-based therapy, have provided a strong link between clinical investigation and basic research. MSCs…”
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Revealed pathophysiological mechanisms of crosslinking interaction of affected vital organs in COVID-19
Published in Comparative clinical pathology (2021)“…SARS-CoV-2 is one of the main serious challenges of human societies, which emerged in December 2019 from China and quickly extends to all parts of the world…”
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Alantolactone inhibits stem-like cell phenotype, chemoresistance and metastasis in PC3 cells through STAT3 signaling pathway
Published in Research in pharmaceutical sciences (01-11-2020)“…Background and purpose: Cancer stem cells (CSCs), as the subpopulation of cancer cells, are associated with carcinogenesis, chemoresistance, and metastasis in…”
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14
Application of sesquiterpene lactone: A new promising way for cancer therapy based on anticancer activity
Published in Biomedicine & pharmacotherapy (01-10-2018)“…Cancer is one of the most dangerous diseases that are rapidly increasing globally. After heart disease, it is the second leading cause of death, accounting for…”
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Vitamin D and potential effects on cancers: a review
Published in Molecular biology reports (01-12-2024)“…Cancer is characterized by the abnormal and uncontrollable division and growth of cells that can infiltrate tissues and alter normal physiological function,…”
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STAT protein family and cardiovascular diseases: overview of pathological mechanisms and therapeutic implications
Published in Molecular biology reports (01-12-2024)“…Globally, cardiovascular diseases (CVD) are one of the significant causes of death and are considered a major concern of human society. One of the most crucial…”
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The Epigenetic Reader Methyl-CpG-Binding Protein 2 (MeCP2) Is an Emerging Oncogene in Cancer Biology
Published in Cancers (09-05-2023)“…Epigenetic mechanisms are gene regulatory processes that control gene expression and cellular identity. Epigenetic factors include the "writers", "readers",…”
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The role of exosomes in the molecular mechanisms of metastasis: Focusing on EMT and cancer stem cells
Published in Life sciences (1973) (01-12-2022)“…Exosomes are cell-derived small membrane-encapsulated vesicles that transfer biomolecules to surrounding cells. Exosomes play fundamental roles in cell-cell…”
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MicroRNAs in esophageal squamous cell carcinoma: Application in prognosis, diagnosis, and drug delivery
Published in Pathology, research and practice (01-12-2022)“…MicroRNAs (miRNAs) play a vital role in various cell biology processes, including cancer formation. These small non-coding RNAs could function as diagnostic…”
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The role of circadian genes in the pathogenesis of colorectal cancer
Published in Gene (15-12-2021)“…•The circadian system plays a significant role in gastrointestinal physiology.•The circadian genes expression is frequently changed in colorectal cancers.•The…”
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