Search Results - "Ghada M.E. Ali"

Medicinal attributes of pyrazolo[1,5-a]pyrimidine based scaffold derivatives targeting kinases as anticancer agents by Nasser S.M. Ismail, Ghada M.E. Ali, Diaa A. Ibrahim, Amira M. Elmetwali

“…Pyrazolo pyrimidines are fused heterocyclic ring systems which known as bioisosteres of adenine, that are necessary for every aspect of cell life…”
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Design, synthesis and biological evaluation of certain CDK2 inhibitors based on pyrazole and pyrazolo[1,5-a] pyrimidine scaffold with apoptotic activity by Ali, Ghada M.E., Ibrahim, Diaa A., Elmetwali, Amira M., Ismail, Nasser S.M.

“…[Display omitted] •19 Compounds were screened against CDK2/cyclin A2 enzyme.•Target compounds were assessed in vitro against MCF-7, HepG2, A549 and Caco-2…”
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