Search Results - "Ghada M. Helal"
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MYD88, NFKB1, and IL6 transcripts overexpression are associated with poor outcomes and short survival in neonatal sepsis
Published in Scientific reports (28-06-2021)“…Toll-like receptor (TLR) family signature has been implicated in sepsis etiopathology. We aimed to evaluate the genetic profile of TLR pathway-related key…”
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Structure and functional impact of seed region variant in MIR-499 gene family in bronchial asthma
Published in Respiratory research (08-09-2017)“…Small non-coding RNAs (microRNAs) have been evolved to master numerous cellular processes. Genetic variants within microRNA seed region might influence…”
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Vitamin K2 (MK-7) Intercepts Keap-1/Nrf-2/HO-1 Pathway and Hinders Inflammatory/Apoptotic Signaling and Liver Aging in Naturally Aging Rat
Published in Antioxidants (30-10-2022)“…Aging is a naturally occurring physiological process with a deleterious impact on various body organs and humans’ well-being. The aging population is…”
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Hair Follicle-Related MicroRNA-34a Serum Expression and rs2666433A/G Variant in Patients with Alopecia: A Cross-Sectional Analysis
Published in Biomolecules (Basel, Switzerland) (19-04-2022)“…Alopecia areata (AA) is a type of immune-mediated alopecia. Recent studies have suggested microRNAs’ (miRNAs) implication in several cellular processes,…”
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Effects of GLP-1 Receptor Activation on a Pentylenetetrazole-Kindling Rat Model
Published in Brain sciences (14-05-2019)“…: To study the possible anti-seizure and neuroprotective effect of glucagon like peptide 1 (GLP1) analogue (liraglutide) in a pentylenetetrazole (PTZ) induced…”
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Chronic valproic acid administration enhances oxidative stress, upregulates IL6 and downregulates Nrf2, Glut1 and Glut4 in rat’s liver and brain
Published in Neuroreport (07-07-2021)“…Valproic acid (VPA) is a powerful antiepileptic drug that was associated with several neurological and hepatic problems especially with increasing its dose and…”
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Overexpression of heat shock protein HSP90AA1 and translocase of the outer mitochondrial membrane TOM34 in HCV-induced hepatocellular carcinoma: A pilot study
Published in Clinical biochemistry (01-01-2019)“…Identification of new molecular markers to enhance early diagnosis, prognosis and/or treatment of hepatocellular carcinoma (HCC) is a need. TOM34…”
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8
Effects of heme oxygenase-1 upregulation on isoproterenol-induced myocardial infarction
Published in The Korean journal of physiology & pharmacology (01-05-2019)“…The present study was designed to examine the effect of heme oxygenase-1 (HO-1) induction by cobalt protoporphyrin (CoPP) on the cardiac functions and…”
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9
Longevity-Related Gene Transcriptomic Signature in Glioblastoma Multiforme
Published in Oxidative medicine and cellular longevity (01-01-2018)“…Glioblastoma multiforme (GBM) (grade IV astrocytoma) has been assumed to be the most fatal type of glioma with low survival and high recurrence rates, even…”
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Chronic valproic acid administration enhances oxidative stress, upregulates IL6 and downregulates Nrf2, Glut1 and Glut4 in rat’s liver and brain
Published in Neuroreport (26-05-2021)“…Valproic acid (VPA) is a powerful antiepileptic drug that was associated with several neurological and hepatic problems especially with increasing its dose and…”
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Journal Article -
11
Effects of heme oxygenase-1 upregulation on isoproterenolinduced myocardial infarction
Published in The Korean journal of physiology & pharmacology (01-05-2019)“…The present study was designed to examine the effect of heme oxygenase- 1 (HO-1) induction by cobalt protoporphyrin (CoPP) on the cardiac functions and…”
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