Search Results - "Gewurz, Henry"
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Interaction of human immunodeficiency virus (HIV) glycans with lectins of the human immune system
Published in Current protein & peptide science (01-08-2006)“…Approximately half of the molecular mass of gp120, the receptor-binding envelope protein of human immunodeficiency virus (HIV), consists of N-linked glycans…”
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Mannose binding lectin (MBL) and HIV
Published in Molecular immunology (01-02-2005)“…The envelope protein (gp120/gp41) of HIV-1 is highly glycosylated with about half of the molecular mass of gp120 consisting of N-linked carbohydrates. While…”
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3
Mannose-binding lectin binds to Ebola and Marburg envelope glycoproteins, resulting in blocking of virus interaction with DC-SIGN and complement-mediated virus neutralization
Published in Journal of general virology (01-09-2005)“…1 Rush St Luke's Medical Center, Department of Immunology and Microbiology, 1653 W. Congress Parkway, Chicago, IL 60612, USA 2 United States Army Medical…”
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Antigenic, electrophoretic and binding alterations of human C-reactive protein modified selectively in the absence of calcium
Published in Molecular immunology (01-01-1983)“…C-Reactive protein (CRP) is a trace component of normal human serum which has a mol. wt of 105,000 and is composed of five apparently identical subunits…”
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Inhibition of platelet aggregation by native and desialised alpha-1 acid glycoprotein
Published in Nature (London) (25-10-1979)“…The alpha-1 acid glycoprotein (orosomucoid; AAG) is a normal constituent of human plasma (650+/-215 microgram ml(-1)) which increases in concentration as much…”
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6
Structure and function of the pentraxins
Published in Current opinion in immunology (01-02-1995)“…Over the past two years, the three-dimensional structure of the serum amyloid P component was defined by X-ray diffraction, the first such visualization of a…”
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Interaction of mannose-binding lectin with primary isolates of human immunodeficiency virus type 1
Published in Journal of general virology (01-04-2000)“…Department of Immunology/Microbiology, Rush University, 1653 West Congress Parkway, Chicago, IL 60612, USA 1 Author for correspondence: Mohammed Saifuddin. Fax…”
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Ficolin binding and lectin pathway activation by acetylated-LDL
Published in Molecular immunology (2007)Get full text
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Roles for C3 and alpha-2 macroglobulin in the transportation and activation of MASP-2 in normal human serum
Published in Molecular immunology (2007)Get full text
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10
Regulation of complement activation by C-reactive protein
Published in Immunopharmacology (01-05-1999)“…C-reactive protein (CRP) is an acute-phase serum protein and a mediator of innate immunity. CRP binds to microbial polysaccharides and to ligands exposed on…”
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Interactions of C-Reactive Protein and Complement with Liposomes
Published in Proceedings of the National Academy of Sciences - PNAS (01-12-1977)“…Interactions between C-reactive protein (CRP) and liposomal model membranes containing phosphatidyl-choline were investigated. These interactions, in the…”
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Complement Activation by Interaction of Polyanions and Polycations
Published in The Journal of immunology (1950) (01-01-1975)“…Interactions of heparin and protamine in fresh human serum, in amounts far below those required for complement depletion by either agent alone, were found to…”
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13
Studies on the Inhibition of C5̄6̄-Induced Lysis (Reactive Lysis)
Published in The Journal of immunology (1950) (01-02-1975)“…Multiple polyanions and polycations were tested for their ability to influence formation of from C, C7, and sheep erythrocytes. Six of 11 polyanions tested,…”
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The complement system in chronic glomerulonephritis: three newly associated aberrations
Published in The Journal of pediatrics (01-01-1971)Get more information
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15
Human serum amyloid P component oligomers bind and activate the classical complement pathway via residues 14-26 and 76-92 of the A chain collagen-like region of C1q
Published in The Journal of immunology (1950) (01-01-1993)“…Serum amyloid P component (SAP) was polymerized using the cleavable cross-linker 3,3'-dithio-bis-(sulfo-succinimidylpropionate) to study its interaction with…”
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Requirement for the Alternative Pathway as Well as C4 and C2 in Complement-Dependent Hemolysis Via the Lectin Pathway
Published in The Journal of immunology (1950) (15-03-1998)“…Mannan-binding lectin (MBL) is a C1q-like molecule opsonic for several micro-organisms. MBL can activate C4, C2, and later acting complement components in the…”
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Binding and complement activation by C-reactive protein via the collagen-like region of C1q and inhibition of these reactions by monoclonal antibodies to C-reactive protein and C1q
Published in The Journal of immunology (1950) (01-04-1991)“…Ligand-complexed C-reactive protein (CRP), like aggregated or complexed IgG, can react with C1q and activate the classical C pathway. Whereas IgG is known to…”
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Mechanism of complement‐dependent haemolysis via the lectin pathway: role of the complement regulatory proteins
Published in Clinical and experimental immunology (01-09-1999)“…Mannan‐binding lectin (MBL) is an acute phase protein which activates the classical complement pathway at the level of C4 and C2 via two novel serine proteases…”
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DNA binds and activates complement via residues 14-26 of the human C1q A chain
Published in The Journal of biological chemistry (15-12-1992)“…The mechanism by which DNA activates the classical complement pathway was investigated, with emphasis upon the C1q binding sites involved. DNA bound to both…”
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Enhancement of lectin pathway haemolysis by immunoglobulins
Published in Clinical and experimental immunology (01-09-1999)“…We recently reported that indicator sheep erythrocytes (E) coated with mannan and sensitized with mannan‐binding lectin (MBL) (E‐M‐MBL) are lysed by human…”
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