Search Results - "Gevorkian, G."

Carnot cycle at finite power: attainability of maximal efficiency by Allahverdyan, Armen E, Hovhannisyan, Karen V, Melkikh, Alexey V, Gevorkian, Sasun G

“…We want to understand whether and to what extent the maximal (Carnot) efficiency for heat engines can be reached at a finite power. To this end we generalize…”
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Electric stimulation of the vagus nerve reduced mouse neuroinflammation induced by lipopolysaccharide by Meneses, G, Bautista, M, Florentino, A, Díaz, G, Acero, G, Besedovsky, H, Meneses, D, Fleury, A, Del Rey, A, Gevorkian, G, Fragoso, G, Sciutto, E

“…Neuroinflammation (NI) is a key feature in the pathogenesis and progression of infectious and non-infectious neuropathologies, and its amelioration usually…”
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Intranasal delivery of dexamethasone efficiently controls LPS‐induced murine neuroinflammation by Meneses, G., Gevorkian, G., Florentino, A., Bautista, M. A., Espinosa, A., Acero, G., Díaz, G., Fleury, A., Pérez Osorio, I. N., del Rey, A., Fragoso, G., Sciutto, E., Besedovsky, H.

“…Summary Neuroinflammation is the hallmark of several infectious and neurodegenerative diseases. Synthetic glucocorticoids (GCs) are the first‐line…”
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Stabilization and anomalous hydration of collagen fibril under heating by Gevorkian, Sasun G, Allahverdyan, Armen E, Gevorgyan, David S, Simonian, Aleksandr L, Hu, Chin-Kun

“…Type I collagen is the most common protein among higher vertebrates. It forms the basis of fibrous connective tissues (tendon, chord, skin, bones) and ensures…”
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Antigenic variability: Obstacles on the road to vaccines against traditionally difficult targets by Servín-Blanco, R., Zamora-Alvarado, R., Gevorkian, G., Manoutcharian, K.

“…Despite the impressive impact of vaccines on public health, the success of vaccines targeting many important pathogens and cancers has to date been limited…”
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Plant-based chimeric HPV-virus-like particles bearing amyloid-β epitopes elicit antibodies able to recognize amyloid plaques in APP-tg mouse and Alzheimer’s disease brains by Gonzalez-Castro, R., Acero Galindo, G., García Salcedo, Y., Uribe Campero, L., Vazquez Perez, V., Carrillo-Tripp, M., Gevorkian, G., Gomez Lim, M. A.

“…The main amyloid-beta (Aβ) variants detected in the human brain are full-length Aβ1–40 and Aβ1–42 peptides; however, a significant proportion of AD brain Aβ…”
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Immunodominant epitope and properties of pyroglutamate-modified Aβ-specific antibodies produced in rabbits by Acero, G, Manoutcharian, K, Vasilevko, V, Munguia, M.E, Govezensky, T, Coronas, G, Luz-Madrigal, A, Cribbs, D.H, Gevorkian, G

“…Abstract N-truncated and N-modified forms of amyloid beta (Aβ) peptide are found in diffused and dense core plaques in Alzheimer's disease (AD) and Down's…”
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Novel amyloid-beta specific scFv and VH antibody fragments from human and mouse phage display antibody libraries by Medecigo, M, Manoutcharian, K, Vasilevko, V, Govezensky, T, Munguia, M.E, Becerril, B, Luz-Madrigal, A, Vaca, L, Cribbs, D.H, Gevorkian, G

“…Abstract Anti-amyloid immunotherapy has been proposed as an appropriate therapeutic approach for Alzheimer's disease (AD). Significant efforts have been made…”
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Thermal (in)stability of type I collagen fibrils by Gevorkian, S G, Allahverdyan, A E, Gevorgyan, D S, Simonian, A L

“…We measured the Young's modulus at temperatures ranging from 20 to 100 degrees C for a collagen fibril that is taken from a rat's tendon. The hydration change…”
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Glassy state of native collagen fibril? by Gevorkian, S. G, Allahverdyan, A. E, Gevorgyan, D. S, Hu, C.-K

“…Our micromechanical experiments show that viscoelastic features of type-I collagen fibril at physiological temperatures display essential dependence on the…”
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Synthetic peptide vaccine against Taenia solium pig cysticercosis: successful vaccination in a controlled field trial in rural Mexico by Huerta, M, de Aluja, A.S, Fragoso, G, Toledo, A, Villalobos, N, Hernández, M, Gevorkian, G, Acero, G, Dı́az, A, Alvarez, I, Avila, R, Beltrán, C, Garcia, G, Martinez, J.J, Larralde, C, Sciutto, E

“…Taenia solium cysticercosis seriously affects human health when localised in the central nervous system (CNS) and causes great economic loss in pig husbandry…”
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Kinetics of the helix-coil transition by Allahverdyan, A. E, Gevorkian, S. G, Simonian, A

“…Based on the Zimm-Bragg model we study cooperative helix-coil transition driven by a finite-speed change of temperature. There is an asymmetry between the coil…”
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Epitope mapping and neuroprotective properties of a human single chain FV antibody that binds an internal epitope of amyloid-beta 1-42 by Solórzano-Vargas, R.S., Vasilevko, V., Acero, G., Ugen, K.E., Martinez, R., Govezensky, T., Vazquez-Ramirez, R., Kubli-Garfias, C., Cribbs, D.H., Manoutcharian, K., Gevorkian, G.

“…Active and passive immunotherapy targeted at the amyloid-beta (Aβ) peptide has been proposed as therapeutic approach against Alzheimer's disease (AD), and…”
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Human single chain Fv antibodies and a complementarity determining region-derived peptide binding to amyloid-beta 1–42 by Manoutcharian, K., Acero, G., Munguia, M.E., Becerril, B., Massieu, L., Govezensky, T., Ortiz, E., Marks, J.D., Cao, C., Ugen, K., Gevorkian, G.

“…A library of phage-displayed human single-chain Fv (scFv) antibodies was selected against the human amyloid-beta peptide (Aβ42). Two new anti-Aβ42…”
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Multiple myeloma by Mendeleeva, Larisa P., Votiakova, Olga M., Rekhtina, Irina G., Osmanov, Evgenii A., Poddubnaya, Irina V., Grivtsova, Liudmila Iu, Falaleeva, Natalia A., Baikov, Vadim V., Kovrigina, Alla M., Nevol’skikh, Aleksei A., Ivanov, Sergei A., Khailova, Zhanna V., Gevorkian, Tigran G.

“…Multiple myeloma…”
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Solitary (extramedullary) plasmocytoma. Clinical recommendations by Falaleeva, Natal’ia A., Terekhova, Alena Iu, Ptushkin, Vadim V., Osmanov, Evgenii A., Poddubnaya, Irina V., Nevol’skikh, Aleksei A., Ivanov, Sergei A., Khailova, Zhanna V., Gevorkian, Tigran G.

“…Solitary (extramedullary) plasmocytoma. Clinical recommendations…”
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Gastric cancer: Russian clinical guidelines by Besova, Nataliia S., Kalinin, Aleksei E., Nered, Sergei N., Triakin, Aleksei A., Gamaiunov, Sergei V., Kozlov, Nikolai A., Stilidi, Ivan S., Karachun, Aleksei M., Kononets, Pavel V., Malikhova, Olga A., Riabov, Andrei B., Khomiakov, Vladimir M., Fedenko, Aleksandr A., Bolotina, Larisa V., Falaleeva, Natalia A., Nevol'skikh, Aleksei A., Ivanov, Sergei A., Khailova, Zhanna V., Gevorkian, Tigran G., Butenko, Aleksei V., Gil'mutdinova, Ilmira R., Eremushkin, Mikhail A., Ivanova, Galina E., Kondrat'eva, Kristina O., Konchugova, Tatiana V., Krutov, Anton A., Obukhova, Olga A., Semiglazova, Tatiana Iu, Filonenko, Elena V., Khulamkhanova, Marina M., Romanov, Aleksandr I.

“…Gastric cancer remains one of the most common malignancies in Russia. Despite steady decrease of gastric cancer incidence it still reaches 24.65 per 100 000…”
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Phage displayed biomolecules as preventive and therapeutic agents by Manoutcharian, K, Gevorkian, G, Cano, A, Almagro, J C

“…Phage display is a powerful technology for selecting and engineering peptides and proteins expressed on the surface of filamentous bacteriophage. The…”
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Further evaluation of the synthetic peptide vaccine S3Pvac against Taenia solium cysticercosis in pigs in an endemic town of Mexico by Sciutto, E, Morales, J, Martínez, J J, Toledo, A, Villalobos, M N, Cruz-Revilla, C, Meneses, G, Hernández, M, Díaz, A, Rodarte, L F, Acero, G, Gevorkian, G, Manoutcharian, K, Paniagua, J, Fragoso, G, Fleury, A, Larralde, R, De Aluja, A S, Larralde, C

“…Taenia solium cysticercosis is a parasitic disease frequently affecting human health and the pig industry in many developing countries. A synthetic peptide…”
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Chronic lymphocytic leukemia/small lymphocytic lymphoma by Nikitin, E. A., Bialik, T. E., Zaritskii, A. Iu, Iseber, L., Kaplanov, K. D., Lopatkina, T. N., Lugovskaia, S. A., Mukhortova, O. V., Osmanov, E. A., Poddubnaya, I. V., Samoilova, O. S., Stadnik, E. A., Falaleeva, N. A., Baikov, V. V., Kovrigina, A. M., Nevol’skikh, A. A., Ivanov, S. A., Khailova, Zh. V., Gevorkian, T. G.

“…Chronic lymphocytic leukemia/small lymphocytic lymphoma. Clinical recommendations…”
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