Search Results - "Gevirtzman, Louis"
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Matrix prior for data transfer between single cell data types in latent Dirichlet allocation
Published in PLoS computational biology (01-05-2023)“…Single cell ATAC-seq (scATAC-seq) enables the mapping of regulatory elements in fine-grained cell types. Despite this advance, analysis of the resulting data…”
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The ModERN Resource: Genome-Wide Binding Profiles for Hundreds of Drosophila and Caenorhabditis elegans Transcription Factors
Published in Genetics (Austin) (01-03-2018)“…To develop a catalog of regulatory sites in two major model organisms, and , the modERN (model organism Encyclopedia of Regulatory Networks) consortium has…”
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The C. elegans embryonic transcriptome with tissue, time, and alternative splicing resolution
Published in Genome research (01-06-2019)“…We have used RNA-seq in to produce transcription profiles for seven specific embryonic cell populations from gastrulation to the onset of terminal…”
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Comprehensive characterization of tissue-specific chromatin accessibility in L2 Caenorhabditis elegans nematodes
Published in Genome research (01-10-2021)“…Recently developed single-cell technologies allow researchers to characterize cell states at ever greater resolution and scale. is a particularly tractable…”
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Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Published in Nature (London) (28-08-2014)“…Discovering the structure and dynamics of transcriptional regulatory events in the genome with cellular and temporal resolution is crucial to understanding the…”
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A modERN resource: identification of Drosophila transcription factor candidate target genes using RNAi
Published in Genetics (Austin) (06-04-2023)“…Abstract Transcription factors (TFs) play a key role in development and in cellular responses to the environment by activating or repressing the transcription…”
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To mock or not: a comprehensive comparison of mock IP and DNA input for ChIP-seq
Published in Nucleic acids research (22-02-2021)“…Abstract Chromatin immunoprecipitation (IP) followed by sequencing (ChIP-seq) is the gold standard to detect transcription-factor (TF) binding sites in the…”
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Whole-body gene expression atlas of an adult metazoan
Published in Science advances (23-06-2023)“…Gene activity defines cell identity, drives intercellular communication, and underlies the functioning of multicellular organisms. We present the single-cell…”
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MIP-MAP: High-Throughput Mapping of Caenorhabditis elegans Temperature-Sensitive Mutants via Molecular Inversion Probes
Published in Genetics (Austin) (01-10-2017)“…Mutants remain a powerful means for dissecting gene function in model organisms such as Massively parallel sequencing has simplified the detection of variants…”
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Corrigendum: Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Published in Nature (London) (03-12-2015)Get full text
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Correction: Corrigendum: Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Published in Nature (London) (03-12-2015)“…Nature 512, 400–405 (2014); doi:10.1038/nature13497 In this Article, when processing C. elegans ChIP-seq libraries, the gene label ZK337.2 (KLU-1, a C2H2…”
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Erratum: Corrigendum: Regulatory analysis of the C. elegans genome with spatiotemporal resolution
Published in Nature (London) (11-11-2015)Get full text
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A high-fidelity cell lineage tracing method for obtaining systematic spatiotemporal gene expression patterns in Caenorhabditis elegans
Published in G3 : genes - genomes - genetics (01-05-2013)“…Advances in microscopy and fluorescent reporters have allowed us to detect the onset of gene expression on a cell-by-cell basis in a systemic fashion. This…”
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The injured colon
Published in Annals of surgery (01-06-1986)“…Controversy continues regarding the initial management of civilian colon injuries. The main issues are the safety of colostomy versus the desirability of…”
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