Search Results - "Geutskens, Sacha B"

Multipotent stromal cells skew monocytes towards an anti-inflammatory interleukin-10-producing phenotype by production of interleukin-6 by Melief, Sara M, Geutskens, Sacha B, Fibbe, Willem E, Roelofs, Helene

“…Multipotent stromal cells have immunomodulatory capacities and have been used in transplantation and autoimmune diseases. One of the effects of multipotent…”
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Epigenetics in atherosclerosis and inflammation by Wierda, Rutger J., Geutskens, Sacha B., Jukema, J. Wouter, Quax, Paul H.A., van den Elsen, Peter J.

“…•  Introduction •  Epigenetics explained ‐  Epigenetic alterations are reversible •  Atherosclerosis •  Epigenetics and association with atherosclerosis • …”
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The chemorepellent Slit3 promotes monocyte migration by Geutskens, Sacha B, Hordijk, Peter L, van Hennik, Paula B

“…Directional migration is an essential step for monocytes to infiltrate sites of inflammation, a process primarily regulated by chemoattractants. Slits are…”
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Multipotent stromal cells skew monocytes towards an anti-inflammatory function: the link with key immunoregulatory molecules by Melief, Sara M, Geutskens, Sacha B, Fibbe, Willem E, Roelofs, Helene

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Control of human hematopoietic stem/progenitor cell migration by the extracellular matrix protein Slit3 by Geutskens, Sacha B, Andrews, William D, van Stalborch, Anne-Marieke D, Brussen, Kim, Holtrop-de Haan, Sandra E, Parnavelas, John G, Hordijk, Peter L, van Hennik, Paula B

“…Patients whose hematopoietic system is compromised by chemo- and/or radiotherapy require transplantation of hematopoietic stem and progenitor cells (HSPCs) to…”
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Dendritic cells and macrophages are essential for the retention of lymphocytes in (peri)-insulitis of the nonobese diabetic mouse: a phagocyte depletion study by Nikolic, Tatjana, Geutskens, Sacha B, van Rooijen, Nico, Drexhage, Hemmo A, Leenen, Pieter J M

“…Dendritic cells (DC) and macrophages (Mphi) are present in high numbers in the pancreas of the non-obese diabetic (NOD) mouse during the diabetogenic process…”
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Post-myocardial Infarct Inflammation and the Potential Role of Cell Therapy by van Zuylen, Vanessa-leigh, den Haan, Melina C., Geutskens, Sacha B., Roelofs, Helene, Fibbe, Willem E., Schalij, Martin J., Atsma, Douwe E.

“…Myocardial infarction triggers reparative inflammatory processes programmed to repair damaged tissue. However, often additional injury to the myocardium occurs…”
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A role for KMT1c in monocyte to dendritic cell differentiation: Epigenetic regulation of monocyte differentiation by Wierda, Rutger J, Goedhart, Marieke, van Eggermond, Marja C J A, Muggen, Alice F, Miggelbrink, Xanne M, Geutskens, Sacha B, van Zwet, Erik, Haasnoot, Geert W, van den Elsen, Peter J

“…Monocytes play a key role in immune system function. Chromatin remodeling is crucial for various differentiation and gene regulation processes and is rather…”
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Epigenetic control of CCR5 transcript levels in immune cells and modulation by small molecules inhibitors by Wierda, Rutger J., Kuipers, Hedwich F., van Eggermond, Marja C. J. A., Benard, Anne, van Leeuwen, Jan C., Carluccio, Silvia, Geutskens, Sacha B., Jukema, J. Wouter, Marquez, Victor E., Quax, Paul H. A., van den Elsen, Peter J.

“…Previously, we have shown that CCR5 transcription is regulated by CREB‐1. However, the ubiquitous pattern of CREB‐1 expression suggests the involvement of an…”
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A role for KMT1c in monocyte to dendritic cell differentiation by Wierda, Rutger J, Goedhart, Marieke, van Eggermond, Marja C.J.A, Muggen, Alice F, Miggelbrink, Xanne M, Geutskens, Sacha B, van Zwet, Erik, Haasnoot, Geert W, van den Elsen, Peter J

“…Abstract Monocytes play a key role in immune system function. Chromatin remodeling is crucial for various differentiation and gene regulation processes and is…”
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Differential expression of stress proteins in human adult astrocytes in response to cytokines by Bajramović, Jeffrey J, Bsibsi, Malika, Geutskens, Sacha B, Hassankhan, Ryan, Verhulst, Karien C, Stege, Gerard J.J, de Groot, Corline J.A, van Noort, Johannes M

“…Various lines of evidence suggest a close relationship between heat shock proteins (hsp) and several autoimmune diseases such as arthritis, diabetes and…”
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Ganciclovir nucleotides accumulate in mitochondria of rat liver cells expressing the herpes simplex virus thymidine kinase gene by van der Eb, Marjolijn M., Geutskens, Sacha B., van Kuilenburg, André B. P., van Lenthe, Henk, van Dierendonck, Jan-Hein, Kuppen, Peter J. K., van Ormondt, Hans, van de Velde, Cornelis J. H., Wanders, Ronald J. A., van Gennip, Albert H., Hoeben, Rob C.

“…Background Ganciclovir exhibits broad‐spectrum activity against DNA viruses such as cytomegaloviruses, herpes simplex viruses, varicella‐zoster virus,…”
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EBV-induced expression and HLA-DR-restricted presentation by human B cells of alpha B-crystallin, a candidate autoantigen in multiple sclerosis by van Sechel, A C, Bajramovic, J J, van Stipdonk, M J, Persoon-Deen, C, Geutskens, S B, van Noort, J M

“…The development of multiple sclerosis is most likely influenced by autoimmune responses to central nervous system myelin proteins as well as by infections with…”
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The stress kit: a new method based on competitive reverse transcriptase–polymerase chain reaction to quantify the expression of human αB-crystallin, Hsp27, and Hsp60 by Bajramović, Jeffrey J., Geutskens, Sacha B., Bsibsi, Malika, Boot, Marit, Hassankhan, Ryan, Verhulst, Karien C., van Noort, Johannes M.

“…Abstract We describe a reverse transcriptase–polymerase chain reaction method for the semiquantitative detection of mRNAs encoding the human heat shock…”
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The stress kit: a new method based on competitive reverse transcriptase–polymerase chain reaction to quantify the expression of human αB-crystallin, Hsp27, and Hsp60 by Bajramović, Jeffrey J., Geutskens, Sacha B., Bsibsi, Malika, Boot, Marit, Hassankhan, Ryan, Verhulst, Karien C., van Noort, Johannes M.

“…We describe a reverse transcriptase–polymerase chain reaction method for the semiquantitative detection of mRNAs encoding the human heat shock proteins…”
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Activation of autoreactive helper T cells by virus-induced presentation of a self antigen by van Sechel, Arianne C., Bajramović, Jeffrey J., Verhulst, Karien C., Geutskens, Sacha B., Tielemans, Margret J.C., Kruisselbrink, Alwine B., van Noort, Johannes M.

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