Search Results - "Getz, T. M."

Tissue factor–positive tumor microvesicles activate platelets and enhance thrombosis in mice by Geddings, J. E., Hisada, Y., Boulaftali, Y., Getz, T. M., Whelihan, M., Fuentes, R., Dee, R., Cooley, B. C., Key, N. S., Wolberg, A. S., Bergmeier, W., Mackman, N.

“…Essentials Cancer patients have a high rate of venous thrombosis (VT) but the underlying mechanisms are unknown. Tumor‐derived, tissue factor‐positive…”
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Novel mouse hemostasis model for real‐time determination of bleeding time and hemostatic plug composition by Getz, T. M., Piatt, R., Petrich, B. G., Monroe, D., Mackman, N., Bergmeier, W.

“…Summary Introduction Hemostasis is a rapid response by the body to stop bleeding at sites of vessel injury. Both platelets and fibrin are important for the…”
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The fibrinogen γA/γ′ isoform does not promote acute arterial thrombosis in mice by Walton, B. L., Getz, T. M., Bergmeier, W., Lin, F.‐C., Uitte de Willige, S., Wolberg, A. S.

“…Summary Background Elevated plasma fibrinogen is associated with arterial thrombosis in humans and promotes thrombosis in mice by increasing fibrin formation…”
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Differential phosphorylation of myosin light chain (Thr)18 and (Ser)19 and functional implications in platelets by GETZ, T. M., DANGELMAIER, C. A., JIN, J., DANIEL, J. L., KUNAPULI, S. P.

“…  Background:  Myosin IIA is an essential platelet contractile protein that is regulated by phosphorylation of its regulatory light chain (MLC) on residues…”
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Go6976 abrogates GPVI‐mediated platelet functional responses in human platelets through inhibition of Syk by GETZ, T. M., MAYANGLAMBAM, A., DANIEL, J. L., KUNAPULI, S. P.

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The fibrinogen [gamma]A/[gamma]' isoform does not promote acute arterial thrombosis in mice by Walton, B L, Getz, T M, Bergmeier, W, Lin, F-C, Uitte de Willige, S, Wolberg, A S

“…Summary Background Elevated plasma fibrinogen is associated with arterial thrombosis in humans and promotes thrombosis in mice by increasing fibrin formation…”
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Dextran sulphate induces fibrinogen receptor activation through a novel Syk-independent PI-3 kinase-mediated tyrosine kinase pathway in platelets by Getz, Todd M, Manne, Bhanu Kanth, Buitrago, Lorena, Mao, Yingying, Kunapuli, Satya P

“…In our attempt to find a physiological agonist that activates PAR3 receptors, we screened several coagulation proteases using PAR4 null platelets. We observed…”
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OC-04 - Tissue factor positive microvesicles activate platelets in vitro and in vivo and enhance thrombosis in mice by Hisada, Y, Geddings, J.E, Boulaftali, Y, Getz, T.M, Whelihan, M, Fuentes, R, Dee, R, Cooley, B.C, Key, N.S, Wolberg, A.S, Bergmeier, W, Mackman, N

“…Introduction Cancer patients have a 4- to 7- fold increased risk of venous thromboembolism (VTE) compared with general population. Most tumor cells express…”
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