Search Results - "Getz, Landon J."

Anti-phage defence through inhibition of virion assembly by Patel, Pramalkumar H., Taylor, Véronique L., Zhang, Chi, Getz, Landon J., Fitzpatrick, Alexa D., Davidson, Alan R., Maxwell, Karen L.

“…Bacteria have evolved diverse antiviral defence mechanisms to protect themselves against phage infection. Phages integrated into bacterial chromosomes, known…”
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Characterization of novel lignocellulose-degrading enzymes from the porcupine microbiome using synthetic metagenomics by Thornbury, Mackenzie, Sicheri, Jacob, Slaine, Patrick, Getz, Landon J, Finlayson-Trick, Emma, Cook, Jamie, Guinard, Caroline, Boudreau, Nicholas, Jakeman, David, Rohde, John, McCormick, Craig

“…Plant cell walls are composed of cellulose, hemicellulose, and lignin, collectively known as lignocellulose. Microorganisms degrade lignocellulose to liberate…”
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Taxonomic differences of gut microbiomes drive cellulolytic enzymatic potential within hind-gut fermenting mammals by Finlayson-Trick, Emma C L, Getz, Landon J, Slaine, Patrick D, Thornbury, Mackenzie, Lamoureux, Emily, Cook, Jamie, Langille, Morgan G I, Murray, Lois E, McCormick, Craig, Rohde, John R, Cheng, Zhenyu

“…Host diet influences the diversity and metabolic activities of the gut microbiome. Previous studies have shown that the gut microbiome provides a wide array of…”
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Tandem tyrosine phosphosites in the Enteropathogenic Escherichia coli chaperone CesT are required for differential type III effector translocation and virulence by Runte, Cameron S., Jain, Umang, Getz, Landon J., Secord, Sabrina, Kuwae, Asaomi, Abe, Akio, LeBlanc, Jason J., Stadnyk, Andrew W., Kaper, James B., Hansen, Anne‐Marie, Thomas, Nikhil A.

“…Summary Enteropathogenic Escherichia coli (EPEC) use a type 3 secretion system (T3SS) for injection of effectors into host cells and intestinal colonization…”
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Angels and Devils: Dilemmas in Dual-Use Biotechnology by Getz, Landon J., Dellaire, Graham

“…Dual-use research, which results in knowledge that can be used for both good and ill, has become increasingly accessible in the internet age to both scientists…”
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The Transcriptional Regulator HlyU Positively Regulates Expression of exsA , Leading to Type III Secretion System 1 Activation in Vibrio parahaemolyticus by Getz, Landon J, Thomas, Nikhil A

“…is a marine bacterium that is globally recognized as the leading cause of seafood-borne gastroenteritis. uses various toxins and two type 3 secretion systems…”
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Addressing the dark matter of gene therapy: technical and ethical barriers to clinical application by Kratzer, Kateryna, Getz, Landon J., Peterlini, Thibaut, Masson, Jean-Yves, Dellaire, Graham

“…Gene therapies for genetic diseases have been sought for decades, and the relatively recent development of the CRISPR/Cas9 gene-editing system has encouraged a…”
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Attenuation of a DNA cruciform by a conserved regulator directs T3SS1 mediated virulence in Vibrio parahaemolyticus by Getz, Landon J, Brown, Justin M, Sobot, Lauren, Chow, Alexandra, Mahendrarajah, Jastina, Thomas, Nikhil A

“…Abstract Pathogenic Vibrio species account for 3–5 million annual life-threatening human infections. Virulence is driven by bacterial hemolysin and toxin gene…”
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Back to Basics: Application of the Principles of Bioethics to Heritable Genome Interventions by Getz, Landon J., Dellaire, Graham

“…Prior to their announcement of the birth of gene-edited twins in China, Dr. He Jiankui and colleagues published a set of draft ethical principles for…”
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Tyrosine Phosphorylation as a Widespread Regulatory Mechanism in Prokaryotes by Getz, Landon J, Runte, Cameron S, Rainey, Jan K, Thomas, Nikhil A

“…Phosphorylation events modify bacterial and archaeal proteomes, imparting cells with rapid and reversible responses to specific environmental stimuli or…”
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Diverse Antiphage Defenses Are Widespread Among Prophages and Mobile Genetic Elements by Getz, Landon J, Maxwell, Karen L

“…Bacterial viruses known as phages rely on their hosts for replication and thus have developed an intimate partnership over evolutionary time. The survival of…”
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We need a Pride in Microbiology Network by Getz, Landon J., de Oliveira, Bruno Francesco Rodrigues, Pérez-López, Edel

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