Search Results - "Getz, G. S."

HDL apolipoprotein-related peptides in the treatment of atherosclerosis and other inflammatory disorders by Getz, G S, Wool, G D, Reardon, C A

“…Elevations of HDL levels or modifying the inflammatory properties of HDL are being evaluated as possible treatment of atherosclerosis, the underlying mechanism…”
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Isoform-specific binding of apolipoprotein E to beta-amyloid by LaDu, M J, Falduto, M T, Manelli, A M, Reardon, C A, Getz, G S, Frail, D E

“…Apolipoprotein E (apoE), particularly the e4 allele, is genetically linked to the incidence of Alzheimer's disease. ApoE is present in the extracellular senile…”
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Site Specificity of Atherosclerosis: Site-Selective Responses to Atherosclerotic Modulators by VanderLaan, Paul A, Reardon, Catherine A, Getz, Godfrey S

“…ABSTRACT—Atherosclerosis is a complex disease process that affects very specific sites of the vasculature. It is recognized that hemodynamic forces are largely…”
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Diet and Murine Atherosclerosis by Getz, Godfrey S, Reardon, Catherine A

“…Lipid-enriched diets are often used to induce or accelerate the rate of atherosclerotic lesion development in murine models of atherosclerosis. It appears that…”
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Natural killer T cells in lipoprotein metabolism and atherosclerosis by Getz, G S, Vanderlaan, P A, Reardon, C A

“…Cells of both the innate and adaptive immune system participate in the development of atherosclerosis, a chronic inflammatory disorder of medium and large…”
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Fasting hypertriglyceridemia in noninsulin-dependent diabetes mellitus is an important predictor of postprandial lipid and lipoprotein abnormalities by Lewis, G F, O'Meara, N M, Soltys, P A, Blackman, J D, Iverius, P H, Pugh, W L, Getz, G S, Polonsky, K S

“…Postprandial lipoprotein metabolism may be important in atherogenesis and has not been studied in detail in noninsulin-dependent diabetes mellitus (NIDDM). We…”
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HDL content and composition in acute phase response in three species: triglyceride enrichment of HDL a factor in its decrease by Cabana, V G, Lukens, J R, Rice, K S, Hawkins, T J, Getz, G S

“…High density lipoprotein (HDL) levels decrease during the acute phase response (APR). We have used the APR model of rabbit, baboon, and mouse to study the…”
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Postprandial lipoprotein metabolism in normal and obese subjects: comparison after the vitamin A fat-loading test by Lewis, G F, O'Meara, N M, Soltys, P A, Blackman, J D, Iverius, P H, Druetzler, A F, Getz, G S, Polonsky, K S

“…Abnormalities in fasting lipid and lipoprotein levels are known to occur in obesity and other hyperinsulinemic states. However, postprandial lipoprotein…”
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The cholesterol facts : a summary of the evidence relating dietary fats, serum cholesterol, and coronary heart disease-a joint statement by the american heart association and the national heart, lung, and blood institute by LA ROSA, J. C, CHAIRMAN, ROBERTSON, R. M, WEISFELDT, M. L, CLEEMAN, J. I, GOTTO, A. M, HUNNINGHAKE, D, GRUNDY, S. M, WFILSON, P. W, CLARKSON, T. B, HAY, J. W, GOODMAN, D. S, CHAIRMAN, V, BUSH, D, CRIQUI, M. H, GETZ, G. S, RAKITA, L

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Macrophage free cholesterol content regulates apolipoprotein E synthesis by Mazzone, T, Gump, H, Diller, P, Getz, G S

“…The relationship between macrophage cholesterol content and apolipoprotein E (apoE) synthesis was studied in mouse peritoneal macrophages. Incubations in…”
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Effect of Apolipoprotein E on Neurite Outgrowth and β‐Amyloid‐Induced Toxicity in Developing Rat Primary Hippocampal Cultures by Puttfarcken, Pamela S., Manelli, Arlene M., Falduto, Michael T., Getz, Godfrey S., LaDu, Mary Jo

“…: The correlation between the ε4 allele of apolipoprotein E (apoE) and Alzheimer's disease is well established. However, the role of apoE in normal as well as…”
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Role of basal triglyceride and high density lipoprotein in determination of postprandial lipid and lipoprotein responses by O'Meara, N M, Lewis, G F, Cabana, V G, Iverius, P H, Getz, G S, Polonsky, K S

“…The present study reports on the interaction between basal triglyceride and high density lipoprotein (HDL) cholesterol in determining the magnitude of…”
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SDS-Stable Complex Formation between Native Apolipoprotein E3 and β-Amyloid Peptides by Munson, Gregory W, Roher, Alex E, Kuo, Yu-Min, Gilligan, Sean M, Reardon, Catherine A, Getz, Godfrey S, LaDu, Mary Jo

“…Extracellular senile plaques composed predominantly of fibrillar amyloid-β (Aβ) are a major neuropathological feature of Alzheimer's disease (AD). Genetic…”
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When Is Atherosclerosis Not Atherosclerosis? by Getz, Godfrey S

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Identification of a new nuclear gene (CEM1) encoding a protein homologous to a beta-keto-acyl synthase which is essential for mitochondrial respiration in Saccharomyces cerevisiae by Harington, A, Herbert, C J, Tung, B, Getz, G S, Slonimski, P P

“…We have analysed a new gene, CEM1, from Saccharomyces cerevisiae. Inactivation of this gene leads to a respiratory-deficient phenotype. The deduced protein…”
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In Vivo Studies of HDL Assembly and Metabolism Using Adenovirus-Mediated Transfer of ApoA-I Mutants in ApoA-I-Deficient Mice by Reardon, Catherine A, Kan, Horng-Yuan, Cabana, Veneracion, Blachowicz, Lydia, Lukens, John R, Wu, Qingzhou, Liadaki, Kalliopi, Getz, Godfrey S, Zannis, Vassilis I

“…We have used adenovirus-mediated gene transfer in apoA-I-deficient (A-I-/-) mice to probe the in vivo assembly and metabolism of HDL using apoA-I variants,…”
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Neurons of the Human Frontal Cortex Display Apolipoprotein E Immunoreactivity: Implications for Alzheimerʼs Disease by Metzger, Randy E, LaDu, Mary Jo, Pan, Jia B, Getz, Godfrey S, Frail, Donald E, Falduto, Michael T

“…Apolipoprotein E (apoE) is a plasma protein that regulates lipid transport and cholesterol homeostasis. In humans, apoE occurs as 3 major isoforms (apoE2, E3,…”
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Extrahepatic synthesis of apolipoprotein E by Driscoll, D M, Getz, G S

“…Apolipoprotein E (apoE) synthesis has been examined in rat and guinea pig tissues using in vitro translation and [35S]methionine labeling of tissue slices. A…”
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Characterization of cholesteryl ester transfer protein inhibitor from plasma of baboons (Papio sp.) by KUSHWAHA, R. S, HASAN, S. Q, MCGILL, H. C, GETZ, G. S, DUNHAM, R. G, KANDA, P

“…Selective breeding has produced families of baboons that accumulate large high density lipoproteins (HDL1) when challenged with a high cholesterol and high fat…”
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Serum amyloid A and high density lipoprotein participate in the acute phase response of Kawasaki disease by CABANA, V. G, GIDDING, S. S, GETZ, G. S, CHAPMAN, J, SHULMAN, S. T

“…In this study we report changes in HDL concentration and composition in acute and convalescent Kawasaki disease. Notable reductions in plasma HDL-cholesterol…”
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