Search Results - "Geter, D."

Liver tumor formation in female rat induced by fluopyram is mediated by CAR/PXR nuclear receptor activation by Tinwell, H., Rouquié, D., Schorsch, F., Geter, D., Wason, S., Bars, R.

“…•The MOA of fluopyram-induced liver tumors was investigated in the female rat.•CAR/PXR nuclear receptor activation was shown to be the first key event of the…”
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Thyroid tumor formation in the male mouse induced by fluopyram is mediated by activation of hepatic CAR/PXR nuclear receptors by Rouquié, D., Tinwell, H., Blanck, O., Schorsch, F., Geter, D., Wason, S., Bars, R.

“…•The MOA of fluopyram-induced thyroid tumors was investigated in the male mouse.•CAR/PXR nuclear receptor activation was shown to be the first key event of the…”
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Simultaneous quantitation of testosterone and estradiol in human cell line (H295R) by liquid chromatography/positive atmospheric pressure photoionization tandem mass spectrometry by Zhang, F., Rick, D. L., Kan, L. H., Perala, A. W., Geter, D. R., Lebaron, M. J., Bartels, M. J.

“…The possible interaction of environmental contaminants with the endocrine system has been an environmental concern since the early 1990s. To examine these…”
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The effects of a high animal fat diet on the induction of aberrant crypt foci in the colons of male F344/N rats exposed to trihalomethanes in the drinking water by Geter, David R, George, Michael H, Moore, Tanya M, Kilburn, Steve R, Huggins-Clark, Gloria, DeAngelo, Anthony B

“…Aberrant crypt foci (ACF), identified as putative precursor lesions in the development of colon cancer, were induced by brominated trihalomethanes (THMs)…”
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Mode of action and human relevance analysis for nuclear receptor-mediated liver toxicity: A case study with phenobarbital as a model constitutive androstane receptor (CAR) activator by Elcombe, Clifford R., Peffer, Richard C., Wolf, Douglas C., Bailey, Jason, Bars, Remi, Bell, David, Cattley, Russell C., Ferguson, Stephen S., Geter, David, Goetz, Amber, Goodman, Jay I., Hester, Susan, Jacobs, Abigail, Omiecinski, Curtis J., Schoeny, Rita, Xie, Wen, Lake, Brian G.

“…Abstract The constitutive androstane receptor (CAR) and pregnane X receptor (PXR) are important nuclear receptors involved in the regulation of cellular…”
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Molecular biomarkers of oxidative stress associated with bromate carcinogenicity by Delker, Don, Hatch, Gary, Allen, James, Crissman, Bobby, George, Michael, Geter, David, Kilburn, Steve, Moore, Tanya, Nelson, Gail, Roop, Barbara, Slade, Ralph, Swank, Adam, Ward, William, DeAngelo, Anthony

“…Potassium bromate (KBrO 3) is a chemical oxidizing agent found in drinking water as a disinfection byproduct of surface water ozonation. Chronic exposures to…”
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Pigmented skin tumors in gizzard shad (Dorosoma cepedianum) from the south-central United States: Range extension and further etiological studies by Geter, David R., Hawkins, William E., Means, Jay C., Ostrander, Gary K.

“…Previous studies reported skin tumors diagnosed as pigmented subcutaneous spindle‐cell neoplasms in 22% of gizzard shad (Dorosoma cepedianum) from Lake of the…”
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Missed appropriations: Uncovering Heidegger's debt to Kierkegaard in "Being and Time" by Geter, Kenneth D

“…It is widely held that Martin Heidegger appropriated several existential concepts from Søren Kierkegaard in his 1927 work, Being and Time. Most scholars agree…”
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Early alterations in protein and gene expression in rat kidney following bromate exposure by Ahlborn, Gene J., Delker, Don A., Roop, Barbara C., Geter, David R., Allen, James W., DeAngelo, Anthony B., Winnik, Witold M.

“…Bromate, a common disinfectant byproduct of drinking water ozonation, has been linked to human and animal renal toxicity, including renal cell carcinomas in…”
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Developing a Research Agenda and a Comprehensive National Prevention and Response Plan for Rift Valley Fever in the United States by Britch, Seth C, Linthicum, Kenneth J

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The induction of aberrant crypt foci (ACF) in the colons of rats by trihalomethanes administered in the drinking water by DeAngelo, Anthony B, Geter, David R, Rosenberg, Daniel W, Crary, C.Ken, George, Michael H

“…Bromodichloromethane (BDCM) and bromoform (TBM) have been demonstrated to be colon carcinogens in male and female F344/N rats following administration by corn…”
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Tribromomethane exposure and dietary folate deficiency in the formation of aberrant crypt foci in the colons of F344/N rats by Geter, David R., Moore, Tanya M., George, Michael H., Kilburn, Steve R., Allen, James W., Nelson, Gail M., Winkfield, Ernest, DeAngelo, Anthony B.

“…Folate and folic acid are forms of the B vitamin that are involved in the synthesis, repair, and functioning of DNA and are required for the production and…”
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Geospatial field applications within United States Department of Agriculture, Veterinary Services by FitzMaurice, Priscilla L, Freier, Jerome E, Geter, Kenneth D

“…Epidemiologists, veterinary medical officers and animal health technicians within Veterinary Services (VS) are actively utilising global positioning system…”
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Geospatial analysis and modelling in the prevention and control of animal diseases in the United States by Freier, Jerome E, Miller, Ryan S, Geter, Kenneth D

“…In 2008, the hypoxic zone in the Gulf of Mexico, measuring 20720 km2, was one of the two largest reported since measurement of the zone began in 1985. The…”
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Vehicle and Mode of Administration Effects on the Induction of Aberrant Crypt Foci in the Colons of Male F344/N Rats Exposed to Bromodichloromethane by Geter, David R., George, Michael H., Moore, Tanya M., Kilburn, Steve, Huggins-Clark, Gloria, DeAngelo, Anthony B.

“…Bromodichloromethane (BDCM) and tribromomethane given by corn oil gavage were previously found to induce neoplasia in the large intestine of rats. Our chronic…”
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p-Nitrophenol and glutathione response in medaka ( Oryzias latipes) exposed to MX, a drinking water carcinogen by Geter, David R., Fournie, John W., Brouwer, Marius H., DeAngelo, Anthony B., Hawkins, William E.

“…When chlorine is introduced into public drinking water for disinfection, it can react with organic compounds in surface waters to form toxic by-products such…”
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MX [3-Chloro-4-(Dichloromethyl)-5-Hydroxy-2[5H]-Furanone], A Drinking-Water Carcinogen, Does Not Induce Mutations in the Liver of Cii Transgenic Medaka (Oryzias latipes) by Geter, David R., Winn, Richard N., Fournie, John W., Norris, Michelle B., DeAngelo, Anthony B., Hawkins, William E.

“…Mutagenicity assays with Salmonella have shown that 3-chloro-4-(dichloromethyl)-5-hydroxy-2[5 H]-furanone (MX), a drinking-water disinfection by-product, is a…”
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